Disease
Microbiota ☳
Metabolome
Factor
Bacteroidaceae ⇒ Bacteroides {10000109}
Record Keys
Parent:
Definition: Bacteroides
Details
Initialisation date: 2020-09-06
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: Anti fibrosis
Notes:
[ ] Shared Reference Notes
[1.1 ] - The identified microbiome pattern of healthy ageing is characterized by a depletion of core genera found across most humans, primarily Bacteroides .
- Retaining a high Bacteroides dominance into older age, or having a low gut microbiome uniqueness measure, predicts decreased survival in a 4-year follow-up.
[1.2 ] - Patients with #Major depressive disorder showed a statistically significant overrepresentation of Bacteroides enterotype 2 compared to controls.
[1.3 ] - Bacteroides is a common member of the gut microbiome and plays important, symbiotic roles, such as modulation and regulation of the immune system, maintenance of intestinal integrity, and carbohydrate digestion.
- Bacteroides organisms are major producers of short-chain fatty acids, which have been shown to support host immune homeostasis both locally and systemically
- γ-aminobutyric acid (#GABA ) production by human-derived Bacteroides is widespread, and there is a correlation between brain signatures of depression and fecal Bacteroides levels in patients with #Major depressive disorder .
[1.4 ] [#Non-alcoholic fatty liver disease ] - Some Bacteroides species have been reported to be protective against MAFLD
[#Steatohepatitis ] - Bacteroides was negatively associated with advanced steatosis
- Some species of Bacteroides have been associated with progression to advanced liver fibrosis
[1.5 ] - Bacteroides predominate with protein and #Animal fat consumption .
[1.6 ] [#Galactooligosaccharides & modified mogrosides Sweetener ] - Significant growth during the fermentation at 10 h of bacterial populations includes #Bifidobacterium , Bacteroides , #Enterococcus , and #Clostridium coccoides .
- significant increase in production of SCFA in mMV-GOS at 10 h of fermentation, mainly seen in #Acetate and #Propionate production
[1.7 ] [#Alzheimer’s disease ] - Increasing the relative abundance of Bacteroides and #Faecalibacterium may improve cognitive levels
[1.8 ] - Members of the genera #Oscillospira and #Coprococcus in the cecum, as well as #Faecalibacterium prausnitzii and members of the genus Bacteroides in the ileum > negatively correlated with #Fibrosis .
[1.9 ] [#Carbohydrate diet , #High protein / animal fat diets ] - high protein animal fat diets are associated with Bacteroides , whereas diets high in carbohydrates are associated with a high prevalence of #Prevotella
[#Chronic fatigue syndrome ] - Several studies reported a reduction of a butyrate-producing Bacteroides species in ME/CFS
[#Resistant starch ] - RS consumption was associated with an increased abundance of either Bacteroides or #Prevotella transcripts.
[1.11 ] - #Butyrate inhibits gut microbiome Bacteroides
- #Butyrate inhibition depends on which #Sugar a given Bacteroides strain uses
- Core genome variation in Acyl-CoA enzymes mediates #Butyrate defense
- Each Bacteroides unique fitness landscape unpredictable by interaction of ecosystem parts
[1.12 ] - #Firmicutes and Bacteroides are the main #Butyrate producing phyla
[1.13 ] [#Diabetes Type 1 ] [#Lipopolysaccharide ] - lipopolysaccharides biosynthesis in Bacteroides MAGs (metagenome-assembled genomes) and #Sulfate reduction in #Anaerostipes MAGs as functional signatures of MAGs with positive IA-association (Islets autoantibody)
[#Diabetes Type 1 ] [#Lipopolysaccharide ] - LPS produced by the Bacteroides species in gut microbiota has immunoinhibitory properties that may impede early immune education and contribute to the development of T1D.
[1.14 ] -The antibacterial and antitumor defensin (HBD1) showed decreased levels in #Prostate cancer patients, while others (HBD2 and 3) were considerably increased.
- Abundance of #Staphylococcus , #Corynebacterium and #Oxyphotobacteria genera was significantly higher, the abundance of #Faecalibacterium and Bacteroides genera were significantly lower in prostate tumor samples compared to non-tumor samples.
- Bacteroides , Parabacteroides and #Faecalibacterium abundance gradually decreased with the combined increase in HBD2 and HBD3.
- Higher #Corynebacterium and #Staphylococcus abundances were measured together with higher HBD2 and HBD3 urinary levels.
[1.15 ] [#Parkinson’s Disease ] - an abundance of Bacteroides (Gram-negative bacteria present in the gut microbiome) is associated with the severity of motor symptoms in PD
[1.16 ] [#Irritable bowel syndrome ] - symptom severity is related to characteristic alterations of gut microbiota, including reduced diversity, reduced exhaled methane, relative reduction of #Methanobacteriales and #Prevotella enterotype, and abundance of Bacteroides enterotype.
- Bacteroides were found to be increased in patients with IBS-D and were associated with mucosal low-grade inflammation.
[1.17 ] [#Animal fat consumption ] - diet with high content of animal fat was consumed Bacteroides -dominated enterotype was present
[1.18 ] [#Lipopolysaccharide ] [#Antibiotic Therapy , #Condition of chronic stress ] - stressor exposed mice had significantly altered community structure of their gut microbiota, with decreased abundance of the genus Bacteroides and increased abundance of the genus #Clostridium . This was accompanied by increased circulating levels of IL-6 and monocyte chemoattractant protein 1 (MCP-1).
- In a follow-up experiment, animals were fed an antibiotic cocktail in the morning and evening by oral gavage, beginning three days before the stressor and continuing to the end of the experiment. Antibiotic treatment prevented the increases in IL-6 and MCP-1.
- mice receiving the stressor had elevated hepatic portal blood levels of LPS (from the gastrointestinal draining vein) and elevated mRNA expression of IL-1β, IL-6, and TNF in the hypothalamus, though no changes in circulating cytokines. Pretreatment with L. farciminis, antibiotics, and ML-7 all prevented these increases.
[1.19 ] [#CVD ] [#Short Chain Fatty Acid ] [#Probiotic , #Probiotic (Bifidobacter and Lactobacilus) ] - Short-chain fatty acids and secondary #Bile Acids can decrease #Cholesterol levels by regulating #Cholesterol metabolism.
- Microbial #Bile Salt hydrolases can increase #Cholesterol disposal rates by accelerating its conversion to #Bile Acids .
- Probiotics from the genera Lactobacillus and Bifidobacterium are efficient reducers of #Cholesterol levels in clinical studies.
- Several candidate next-generation probiotics, including #Akkermansia muciniphila , Bacteroides spp., #Clostridium spp., #Christensenella minuta , Eubacterium spp., and #Faecalibacterium prausnitzii , have been shown to decrease #Cholesterol levels in human or animal studies.
- At the genus level, #Prevotella and Bacteroides were significantly enriched in the #Meditation group.
- Two beneficial bacterial genera (#Megamonas and #Faecalibacterium ) were significantly enriched in the #Meditation group.
- Several pathways—including glycan biosynthesis, metabolism and lipopolysaccharide biosynthesis—were significantly enriched in the #Meditation group.
- Plasma levels of clinical risk factors were significantly decreased in the #Meditation group, including total #Cholesterol and apolipoprotein B.
[1.21 ] [#Graves’ disease , #Graves’ orbitopathy ] - when patients were hyperthyroid and TRAB positive, #Actinobacteria were significantly increased and Bacteroidetes significantly decreased in GD/GO compared with HC.
- Bacteroides displayed positive and negative correlations with TSH and FT4 respectively and was also significantly associated with #Smoking in GO, #Smoking is a risk factor for GO but not GD.
[1.22 ] [#Diabetes Type 2 ] - The genus #Blautia was one of the most represented genera in both groups enriched in group T2D.
- #Lachnoclostridium were more abundant in the microbiome profiles of diabetic patients.
- There are anomalies in the genera Bacteroides and #Prevotella , both of which are increased in the T2D, both genera are #Propionate producers.
[1.23 ] [#Cesarean section , #Vaginally delivery ] - Bacteroides indeed disappears around week 1 of life in CS-born infants after initial colonization, whereas colonization persists in those vaginally born.
[1.24 ] [#Polyphenol ] [#Polyphenol-rich supplementation ] - Four dietary polyphenols (rutin, #Quercetin , chlorogenic acid, and #Caffeic acid ) can reduce the ratio of #Firmicutes to Bacteroides in in vitro gut microbiota experiments.
[1.25 ] [#Colitis , #Diabetes Type 1 ] - The protein expressed by the Bacteroides is almost identical to a protein expressed by insulin-producing cells in the pancreas.
- The CD8 lymphocytes can mistakenly attack the pancreatic cells and cause type 1 diabetes.
Intervention in Disease [ ]
Author: MetaBiom
Identifier: 10000109
URL: https://www.metabiom.org/microbiota/8/bacteroides
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Gut microbiome pattern reflects healthy ageing and predicts survival in humans [2021] [Research] [nature metabolism] [Journal] [80001714 ]
[1.2 ] The Role of Gut Microbiota in the High-Risk Construct of Severe Mental Disorders: A Mini Review [2021] [Review] [Frontiers in Psychiatry] [Journal] [80001729 ]
[1.3 ] A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients [2021] [Research] [mBio] [Journal] [80001737 ]
[1.4 ] Gut microbiome profiles associated with steatosis severity in metabolic associated fatty liver disease [2021] [Research] [Hepatoma Research] [Journal] [80001824 ]
[1.5 ] Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model [2021] [Research] [Microbiome] [Journal] [80001840 ]
[1.6 ] Prebiotic Potential of a New Sweetener Based on Galactooligosaccharides and Modified Mogrosides [2022] [Study] [Journal of Agricultural and Food Chemistry] [Journal] [80001847 ]
[1.7 ] Composition of intestinal flora affects the risk relationship between Alzheimer’s disease/Parkinson’s disease and cancer [2022] [Review] [Biomedicine & Pharmacotherapy] [Journal] [80002199 ]
[1.8 ] Gut Microbiome and Organ Fibrosis [2022] [Review] [Nutrients] [Journal] [80002265 ]
[1.9 ] The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) [2022] [Review] [Frontiers in Immunology] [Journal] [80002273 ]
[1.10 ] Resistant starch type 2 and whole grain maize flours enrich different intestinal bacteria and metatranscriptomes [2022] [Study] [Journal of Functional Foods] [Journal] [80002313 ]
[1.11 ] Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite [2022] [Study] [Cell] [Journal] [80002317 ]
[1.12 ] Role of Butyrate, a Gut Microbiota Derived Metabolite, in Cardiovascular Diseases: A comprehensive narrative review [2022] [Review] [Frontiers in Pharmacology] [Journal] [80002402 ]
[1.13 ] Islet autoantibody seroconversion in type-1 diabetes is associated with metagenome-assembled genomes in infant gut microbiomes [2022] [Study] [Nature communications] [Journal] [80002455 ]
[1.14 ] Bladder Tissue Microbiome Composition in Patients of Bladder Cancer or Benign Prostatic Hyperplasia and Related Human Beta Defensin Levels [2022] [Study] [biomedicines] [Journal] [80002488 ]
[1.15 ] Nutrition and Gut–Brain Pathways Impacting the Onset of Parkinson’s Disease [2022] [Review] [Nutrients] [Journal] [80002546 ]
[1.16 ] Gut microbiota signatures and modulation in irritable bowel syndrome [2022] [Review] [Microbiome Research Reports] [Journal] [80002578 ]
[1.17 ] Correlation between human gut microbiome and diseases [2022] [Review] [Infectious Medicine] [Journal] [80002594 ]
[1.18 ] Finding intestinal fortitude: Integrating the microbiome into a holistic view of depression mechanisms, treatment, and resilience [2020] [Review] [Neurobiology of Disease] [Journal] [80002658 ]
[1.19 ] Gut microbiome-mediated mechanisms for reducing cholesterol levels: implications for ameliorating cardiovascular disease [2023] [Research] [Trends in Microbiology] [Journal] [80002694 ]
[1.20 ] Alteration of faecal microbiota balance related to long-term deep meditation [2023] [Study] [General Psychiatry] [Journal] [80002709 ]
[1.21 ] Gut microbiome associated with Graves’ disease and Graves’ orbitopathy: the INDIGO multi-centre European study [2023] [Study] [The Journal of Clinical Endocrinology & Metabolism] [Journal] [80002719 ]
[1.22 ] Variation of butyrate production in the gut microbiome in type 2 diabetes patients [2023] [Clinical study] [International Microbiology] [Journal] [80002763 ]
[1.23 ] Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites [2023] [Study] [Cell Host & Microbe] [Journal] [80002803 ]
[1.24 ] Dietary Polyphenol, Gut Microbiota, and Health Benefits [2022] [Review] [Antioxidants] [Journal] [80002820 ]
[1.25 ] A Gut Microbial Mimic that Hijacks Diabetogenic
Autoreactivity to Suppress Colitis [2017] [Research] [Cell] [Journal] [80000054 ]
[1.26 ] Skin microbiome differences relate to the grade of acne vulgaris [2019] [Journal of Dermatology] [Journal] [80001179 ]
[1.27 ] Persistent gut microbial dysbiosis in children with acute lymphoblastic leukemia (ALL) during chemotherapy [2020] [Microbial Ecology] [Journal] [80001424 ]
[1.28 ] Gut microbiota compositional and functional fingerprint in patients with alcohol use disorder and alcohol-associated liver disease [2020] [Liver International] [Journal] [80001386 ]
[1.29 ] Gut microbiota alterations in Alzheimer’s Disease [2017] [Scientific Reports] [Journal] [80000621 ]
[1.30 ] Stratification of the Gut Microbiota Composition Landscape across the Alzheimer’s Disease Continuum in a Turkish Cohort [2022] [Study] [mSystems] [Journal] [80002303 ]
[1.31 ] Alterations in the human gut microbiome in anti-N-methyl-D-aspartate receptor encephalitis [2019] [Annals of Clinical and Translational Neurology] [Journal] [80001157 ]
[1.32 ] Lower airway microbiota and mycobiota in children with sever asthma [2018] [Journal of Allergy and Clinical Immunology] [Journal] [80001065 ]
[1.33 ] Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture [2019] [Scientific Reports] [Journal] [80000949 ]
[1.34 ] Helicobacter pylori infection aggravates dysbiosis of gut microbiome in children with gastritis [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001277 ]
[1.35 ] Differences in fecal microbial metabolites and microbiota of children with autism spectrum disorders [2018] [Anaerobe] [Journal] [80000798 ]
[1.36 ] Disturbance of trace element and gut microbiota profiles as indicators of autism spectrum disorder: a pilot study of Chinese children [2019] [Environmental Research] [Journal] [80000909 ]
[1.37 ] Gut microbiota changes in patients with bipolar depression [2019] [Advanced Science] [Journal] [80001106 ]
[1.38 ] Duodenal and faecal microbiota of celiac children: molecular, phenotype and metabolome characterization. [2011] [BMC Microbiology] [Journal] [80000529 ]
[1.39 ] Imbalance in the composition of the duodenal microbiota in children with coeliac disease [2007] [Journal of Medical Microbiology] [Journal] [80000827 ]
[1.40 ] Alteration of the gut microbiota in Chinese population with chronic kidney disease [2017] [Scientific Reports] [Journal] [80000616 ]
[1.41 ] Gut microbiome patterns depending on children’s psychosocial stress: reports versus biomarkers [2019] [Brain, Behavior, and Immunity] [Journal] [80001328 ]
[1.42 ] Alterations of Bacteroides sp., Neisseria sp., Actinomyces sp., and Streptococcus sp. populations in the oropharyngeal microbiome are associated with liver cirrhosis and pneumonia. [2015] [BMC Infectious Diseases] [Journal] [80000609 ]
[1.43 ] Hepatocellular carcinoma is associated with gut microbiota profile and inflammation in nonalcoholic fatty liver disease [2018] [Hepatology] [Journal] [80000791 ]
[1.44 ] The gut microbiota in collagenous colitis shares characteristics with inflammatory bowel diseas-associated dysbiosis [2019] [Clinical and Translational Gastroenterology] [Journal] [80001117 ]
[1.45 ] Microbial dysbiosis in colorectal cancer (CRC) patients [2011] [PLOS ONE] [Journal] [80000252 ]
[1.46 ] Microbiota disbiosis is associated with colorectal cancer. [2015] [Frontiers in Microbiology] [Journal] [80000302 ]
[1.47 ] The intestinal microbiota associated with cardiac valve calcification differs from that of coronary artery disease [2019] [Atherosclerosis] [Journal] [80000915 ]
[1.48 ] The altered gut microbiota in adults with cystic fibrosis [2017] [BMC Microbiology] [Journal] [80000425 ]
[1.49 ] Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study [2013] [BMC Medicine] [Journal] [80000311 ]
[1.50 ] How ocular surface microbiota debuts in type 2 diabetes mellitus [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001133 ]
[1.51 ] Understanding the gut-kidney axis among biopsy-proven diabetic nephropathy, type 2 diabetes mellitus and healthy controls: an analysis of the gut microbiota composition [2019] [Acta Diabetologica] [Journal] [80001227 ]
[1.52 ] Identification of an intestinal microbiota signature associated with hospitalized patients with diarrhea [2019] [Acta Microbiologica et Immunologica Hungarica] [Journal] [80001053 ]
[1.53 ] Potential contribution of the uterine microbiome in the development of endometrial cancer. [2016] [Genome Medicine] [Journal] [80000482 ]
[1.54 ] Alteration in the gastric microbiota and its restoration by probiotics in patients with functional dyspepsia [2017] [BMJ Open Gastroenterology] [Journal] [80000622 ]
[1.55 ] Detection of microbial 16S rRNA gene in the serum of patients with gastric cancer [2019] [Frontiers in Oncology] [Journal] [80001153 ]
[1.56 ] Association between fecal microbiota and generalized anxiety disorder: severity and early treatment response [2019] [Journal of Affective Disorders] [Journal] [80001071 ]
[1.57 ] Microbiome and its relation to gestational diabetes [2019] [Endocrine] [Journal] [80000966 ]
[1.58 ] Altered gut microbiota in Chinese children with autism spectrum disorders_DUBLICATE [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000977 ]
[1.59 ] Gut microbiota dysbiosis in patients with hepatitis B virus-induced chronic liver disease covering chronic hepatitis, liver cirrhosis and hepatocellular carcinoma [2020] [Journal of Viral Hepatitis] [Journal] [80001388 ]
[1.60 ] Specificities of the fecal microbiota in inflammatory bowel disease [2006] [Inflammatory Bowel Diseases] [Journal] [80000283 ]
[1.61 ] Alterations of microbiota in urine from women with interstitial cystitis [2012] [BMC Microbiology] [Journal] [80000409 ]
[1.62 ] Fecal microbiota in patients with irritable bowel syndrome compared with healthy controls using real-time polymerase chain reaction: an evidence of dysbiosis. [2015] [Digestive Diseases and Sciences] [Journal] [80000236 ]
[1.63 ] Higher Intakes of Potassium and Magnesium, but Not Lower Sodium, Reduce Cardiovascular Risk in the Framingham Offspring Study [2021] [Study] [Nutrients] [Journal] [80002345 ]
[1.64 ] Structural alterations of faecal and mucosa-associated bacterial communities in irritable bowel syndrome [2012] [Environmental Microbiology Reports] [Journal] [80000629 ]
[1.65 ] Evidence for a distinct gut microbiome in kidney stone formers compared to non-stone formers [2016] [Urolithiasis] [Journal] [80000544 ]
[1.66 ] Specific gut microbiome signature predicts the early-stage lung cancer [2020] [Gut microbes] [Journal] [80001413 ]
[1.67 ] Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders [2020] [Research] [Advanced Science] [Journal] [80001465 ]
[1.68 ] Menopause Is Associated with an Altered Gut Microbiome and Estrobolome, with Implications for Adverse Cardiometabolic Risk in the Hispanic Community Health Study/Study of Latinos [2022] [Study] [mSystems] [Journal] [80002528 ]
[1.69 ] Gut microbiota in early pediatric multiple sclerosis: a case-control study [2016] [European Journal of Neurology] [Journal] [80000269 ]
[1.70 ] Fecal and blood microbial 16S rRNA gene alteration in Chinese patients with multiple system atrophy and its subtypes [2019] [Journal of Parkinson's Disease] [Journal] [80001176 ]
[1.71 ] Fecal microbiota profile in a group of myasthenia gravis patients [2018] [Scientific Reports] [Journal] [80000824 ]
[1.72 ] Gut microbiome analysis in Neuromyelitis Optica reveals overabundance of Clostridium perfringens [2016] [Annals of Neurology] [Journal] [80000694 ]
[1.73 ] The severity of Nonalcoholic Fatty Liver Disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota [2016] [Hepatology] [Journal] [80000625 ]
[1.74 ] Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities [2019] [Scientific Reports] [Journal] [80001220 ]
[1.75 ] Gut microbiota composition and bone mineral loss-epidemiologic evidence from individuals in Wuhan, China [2019] [Osteoporosis International] [Journal] [80001182 ]
[1.76 ] Identification and characterization of blood and neutrophil-associated microbiomes in patients with severe acute pancreatitis using next-generation sequencing [2018] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000703 ]
[1.77 ] Colonic bacterial composition in Parkinson’s Disease [2015] [Movement Disorders] [Journal] [80000275 ]
[1.78 ] Compositional and functional features of the female premenopausal and postmenopausal gut microbiota [2019] [FEBS Letters] [Journal] [80001233 ]
[1.79 ] Breast tissue, oral and urinary microbiomes in breast cancer [2017] [Oncotarget] [Journal] [80000875 ]
[1.80 ] Preterm infant meconium microbiota transplant induces growth failure, inflammatory activation, and metabolic disturbances in germ-free mice [2021] [Study] [Cell Reports Medicine] [Journal] [80002178 ]
[1.81 ] The cutaneous microbiome in hospitalized patients with pressure ulcers [2020] [Scientific Reports] [Journal] [80001347 ]
[1.82 ] Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis [2019] [Alimentary Pharmacology & Therapeutics] [Journal] [80001214 ]
[1.83 ] The Akkermansia muciniphila is a gut microbiota signature in psoriasis [2018] [Experimental Dermatology] [Journal] [80000744 ]
[1.84 ] Tissue-Associated Bacterial Alterations in Rectal Carcinoma Patients Revealed by 16S rRNA Community Profiling [2016] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000432 ]
[1.85 ] Association between the oral microbiome and brain resting state connectivity in smokers [2019] [NeuroImage] [Journal] [80001075 ]
[1.86 ] Gut microbiota dysbiosis in male patients with chronic traumatic complete spinal cord injury [2018] [Journal of Translational Medicine] [Journal] [80000938 ]
[1.87 ] Comparison of the ocular microbiome between chronic Stevens-Johnson syndrome patients and healthy subjects [2020] [Scientific Reports] [Journal] [80001339 ]
[1.88 ] Characteristics of fecal and mucosa-associated microbiota in Chinese patients with inflammatory bowel disease [2014] [Medicine] [Journal] [80000665 ]
[1.89 ] Alterations of mucosal microbiota in the colon of patients with inflammatory bowel disease revealed by real time polymerase chain reaction amplification of 16S ribosomal ribonucleic acid. [2015] [Indian J Med Res] [Journal] [80000597 ]
[1.90 ] The microbiome in urogenital schistosomiasis and induced bladder pathologies [2017] [PLoS Neglected Tropical Diseases] [Journal] [80001012 ]
[1.91 ] Association study of gut flora in Wilson’s disease through high-throughput sequencing [2018] [Medicine] [Journal] [80000863 ]
[1.92 ] Subgingival dysbiosis in smoker and non-smoker patients with chronic periodontitis [2017] [Molecular Medicine Reports] [Journal] [80000444 ]
[1.93 ] Temporal and long-term gut microbiota variation in allergic disease: a prospective study from infancy to school age [2019] [Allergy] [Journal] [80001034 ]
[1.94 ] Mild cognitive impairment has similar alterations as Alzheimer’s disease in gut microbiota [2019] [Alzheimer's & Dementia] [Journal] [80001081 ]
[1.95 ] Intestinal microbiota composition in patients with amyotrophic lateral sclerosis: establishment of bacterial and archaeal communities analyses [2019] [Chinese Medical Journal] [Journal] [80001111 ]
[1.96 ] Sex-specific associations of infants’ gut microbiome with arsenic exposure in a US population [2018] [Scientific Reports] [Journal] [80000820 ]
[1.97 ] The gut microbiome in atherosclerotic cardiovascular disease [2017] [Nature communications] [Journal] [80000614 ]
[1.98 ] Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting [2017] [Clinical study] [The Journal of Allergy and Clinical Immunology] [Journal] [80000733 ]
[1.99 ] Oral microbiota in autoimmune polyendocrine syndrome type 1 [2018] [Journal of Oral Microbiology] [Journal] [80000749 ]
[1.100 ] Gut microbial profile in biliary atresia: a case-control study [2019] [Journal of Gastroenterology and Hepatology] [Journal] [80001225 ]
[1.101 ] Profiling the urinary microbiota in male patients with bladder cancer in China_DUBLICATE [2018] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001128 ]
[1.102 ] The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole [2019] [PLOS ONE] [Journal] [80001023 ]
[1.103 ] Alterations of gut microbiota in cholestatic infants and their correlation with hepatic function [2018] [Frontiers in Microbiology] [Journal] [80000981 ]
[1.104 ] Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis [2018] [Scientific Reports] [Journal] [80000689 ]
[1.105 ] Dysbiosis of the gut microbiome is associated with CKD5 and correlated with clinical indices of the disease: a case-controlled study [2019] [Journal of Translational Medicine] [Journal] [80001101 ]
[1.106 ] Impact of cigarette smoking on the middle meatus microbiome in health and chronic rhinosinusitis [2015] [International forum of allergy & rhinology] [Journal] [80000887 ]
[1.107 ] Gut microbiome and serum metabolome analyses identify unsaturated fatty acids and butanoate metabolism induced by gut microbiota in patients with chronic spontaneous urticaria [2020] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001363 ]
[1.108 ] Intestinal lesions are associated with altered intestinal microbiome and are more frequent in children and young adults with cystic fibrosis and cirrhosis [2015] [PLOS ONE] [Journal] [80000573 ]
[1.109 ] Altered gut microbiota composition in subjects infected with Clonorchis sinensis [2018] [Frontiers in Microbiology] [Journal] [80000846 ]
[1.110 ] Gut microbiota composition and Clostridium difficile infection in hospitalized elderly individuals: a metagenomic study [2016] [Scientific Reports] [Journal] [80001033 ]
[1.111 ] Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas [2010] [Gut microbes] [Journal] [80000590 ]
[1.112 ] The human gut microbiome as a screening tool for colorectal cancer [2014] [Cancer Prevention Research] [Journal] [80000706 ]
[1.113 ] Gut mucosal microbiome across stages of colorectal carcinogenesis [2015] [Nature communications] [Journal] [80000724 ]
[1.114 ] Characterization of gut microbiota profiles in coronary artery disease patients using data mining analysis of terminal restriction fragment length polymorphism: gut microbiota could be a diagnostic marker of coronary artery disease [2017] [Heart Vessels] [Journal] [80000400 ]
[1.115 ] Mucosa-attached bacterial community in Crohn’s Disease coheres with the Clinical Disease Activity Index [2016] [Environmental Microbiology Reports] [Journal] [80000447 ]
[1.116 ] Reduced abundance of butyrate-producing bacteria species in the fecal microbial community in Crohn’s Disease. [2016] [Digestion] [Journal] [80000250 ]
[1.117 ] Fungal dysbiosis in mucosa-associated microbiota of Crohn’s disease patients [2016] [Journal of Crohn's and Colitis] [Journal] [80000760 ]
[1.118 ] Molecular-phylogenetic characterization of the microbiota in ulcerated and non-ulcerated regions in the patients with Crohn’s Disease [2012] [PLOS ONE] [Journal] [80000576 ]
[1.119 ] Altered stool microbiota of infants with cystic fibrosis shows a reduction in genera associated with immune programming from birth [2019] [Journal of Bacteriology] [Journal] [80001174 ]
[1.120 ] Gut microbiome and serum metabolome analyses identify molecular biomarkers and altered glutamate metabolism in fibromyalgia [2019] [EBioMedicine] [Journal] [80001184 ]
[1.121 ] Gallstone Disease and Bacterial Metabolic Performance of Gut Microbiota in Middle-Aged and Older Patients [2022] [Clinical study] [International Journal of General Medicine] [Journal] [80002433 ]
[1.122 ] Gut microbiota shifts in patients with gastric cancer in perioperative period [2019] [Medicine] [Journal] [80001110 ]
[1.123 ] Reduced anti-inflammatory gut microbiota are associated with depression and anhedonia [2020] [Journal of Affective Disorders] [Journal] [80001308 ]
[1.124 ] Alterations of the gut microbiota in Hashimoto’s Thyroiditis patients [2018] [Thyroid] [Journal] [80000751 ]
[1.125 ] Gut microbial dysbiosis is associated with altered hepatic functions and serum metabolites in chronic hepatitis B patients [2017] [Frontiers in Microbiology] [Journal] [80000704 ]
[1.126 ] Effects of HIV viremia on the gastrointestinal microbiome of young MSM [2019] [AIDS] [Journal] [80000959 ]
[1.127 ] A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. [2014] [PLOS ONE] [Journal] [80000332 ]
[1.128 ] An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. [2014] [Mucosal Immunology] [Journal] [80000343 ]
[1.129 ] Evidence of dysbiosis in the intestinal microbial ecosystem of children and adolescents with primary hyperlipidemia and the potential role of regular hazelnut intake [2018] [FEMS Microbial Ecology] [Journal] [80000699 ]
[1.130 ] The gut microbiome in epilepsy [2020] [Microbial Pathogenesis] [Journal] [80001252 ]
[1.131 ] Altered fecal bacterial composition correlates with disease activity in inflammatory bowel disease and the extent of IL8 induction [2019] [Current Research in Translational Medicine] [Journal] [80001085 ]
[1.132 ] An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota [2012] [Gut] [Journal] [80000591 ]
[1.133 ] Mucosal microbiome profiles polygenic irritable bowel syndrome in Mestizo individuals [2020] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001366 ]
[1.134 ] Altered fecal microbiota composition in patients with major depressive disorder. [2015] [Brain, Behavior, and Immunity] [Journal] [80000265 ]
[1.135 ] Alterations of the gut microbiota in borderline personality disorder [2022] [Research] [Journal of Psychosomatic Research] [Journal] [80002445 ]
[1.136 ] Conjuctival dysbiosis in mucosa-associated lyphoid tissue lymphoma [2019] [Scientific Reports] [Journal] [80001109 ]
[1.137 ] Nonalcoholic fatty liver disease is associated with dysbiosis independent of body mass index and insulin resistance [2018] [Scientific Reports] [Journal] [80000685 ]
[1.138 ] Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss [2010] [Diabetes] [Journal] [80001231 ]
[1.139 ] Dysbiosis of saliva microbiome in patients with oral lichen planus [2020] [BMC Microbiology] [Journal] [80001332 ]
[1.140 ] Dysbiosis of gut microbiota associated with clinical parameters in polycistic ovary syndrome [2017] [Frontiers in Microbiology] [Journal] [80000443 ]
[1.141 ] Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. [2011] [Inflammatory Bowel Diseases] [Journal] [80000242 ]
[1.142 ] Intestinal microbiota is different in women with preterm birth: results from terminal restriction fragment length polymorphism analysis. [2014] [PLOS ONE] [Journal] [80000402 ]
[1.143 ] Comprehensive analysis of serum and fecal bile acid profiles and interaction with gut microbiota in primary biliary cholangitis [2019] [Clinical Reviews in Allergy & Immunology] [Journal] [80000962 ]
[1.144 ] A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis [2019] [Clinical and Experimental Gastroenterology] [Journal] [80000964 ]
[1.145 ] Gut microbial composition in patients with psoriasis [2018] [Scientific Reports] [Journal] [80000690 ]
[1.146 ] Gut microbial dysbiosis is associated with development and progression of radiation enteritis during pelvic radiotherapy [2019] [Journal of Cellular and Molecular Medicine] [Journal] [80001170 ]
[1.147 ] Altered gut microbiota in Rett syndrome [2016] [Microbiome] [Journal] [80000534 ]
[1.148 ] Variations in oral microbiome profiles in rheumatoid arthritis and osteoarthritis with potential biomarkers for arthritis screening [2018] [Scientific Reports] [Journal] [80000809 ]
[1.149 ] Malassezia and Staphylococcus dominate scalp microbiome for seborrheic dermatitis [2020] [Bioprocess and Biosystems Engineering] [Journal] [80001287 ]
[1.150 ] Fecal microbiota signatures of adult patients with different types of short bowel syndrome [2017] [Journal of Gastroenterology and Hepatology] [Journal] [80000662 ]
[1.151 ] Alterations in the gut microbiota of patients with silica-induced pulmonary fibrosis [2019] [Journal of Occupational Medicine and Toxicology] [Journal] [80000939 ]
[1.152 ] Altered mucosal microbiome diversity and disease severity in Sjögren Syndrome [2016] [Scientific Reports] [Journal] [80000347 ]
[1.153 ] Dysbiosis of gut microbiota and short-chain fatty acids in acute ischemic stroke and the subsequent risk for poor functional outcomes [2020] [Research] [Journal of Parenteral and Enteral Nutrition] [Journal] [80001423 ]
[1.154 ] Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients [2019] [International Journal of Cancer] [Journal] [80000975 ]
[1.155 ] Dysbiosis of gut microbiota with reduced tremethylamine-N-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack._DUBLICATE [2015] [Journal of the American Heart Association] [Journal] [80000456 ]
[1.156 ] Terminal Restriction Fragment length Polymorphism Analysis of the Gut Microbiota Profiles of Pediatric Patients with Inflammatory Bowel Disease [2012] [Digestion] [Journal] [80000619 ]
[1.157 ] Dysbiosis in the gut bacterial microbiome of patients with Uveitis, an inflammatory disease of the eye [2018] [Indian Journal of Microbiology] [Journal] [80000796 ]
[1.158 ] Faecal microbial dysbiosis in children with Wiskott-Aldrich syndrome [2020] [Journal of Immunology] [Journal] [80001296 ]
[1.159 ] Long-term daily high-protein, drained yoghurt consumption alters abundance of selected functional groups of the human gut microbiota and fecal short-chain fatty acid profiles in a cohort of overweight and obese women [2022] [Cohort study] [Journal of Functional Foods] [Journal] [80002459 ]
[1.160 ] Gut microbiota associations with diet in irritable bowel syndrome and the effect of low FODMAP diet and probiotics [2020] [Research] [Clinical Nutrition] [Journal] [80001454 ]
[1.161 ] Maternal exposures and the infant gut microbiome: a systematic review with meta-analysis [2020] [Review] [Gut microbes] [Journal] [80001848 ]
[1.162 ] An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson’s disease participants [2023] [Cohort study] [Nature communications] [Journal] [80002769 ]
[1.163 ] Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies [2018] [Research] [Microbiome] [Journal] [80000217 ]
[1.164 ] How Discrimination Gets Under the Skin: Biological Determinants of Discrimination Associated with Dysregulation of the Brain-Gut Microbiome System and Psychological Symptoms [2022] [Study] [Biological Psychiatry] [Journal] [80002702 ]
[1.165 ] Effects of Heat Stress on Gut Microbiome in Rats [2021] [Research] [Indian Journal of Microbiology] [Journal] [80002087 ]
[1.166 ] Drinking Water Source and Intake Are Associated with Distinct Gut Microbiota Signatures in US and UK Populations [2021] [Study] [The Journal of Nutrition] [Journal] [80002257 ]
[1.167 ] A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration [2022] [Review] [Frontiers in Systems Biology] [Journal] [80002487 ]
[1.168 ] Beneficial reconstitution of gut microbiota and control of alpha-synuclein and curli-amyloids-producing enterobacteria, by beta 1,3-1,6 glucans in a clinical pilot study of autism and potentials in neurodegenerative diseases [2021] [Study] [medRXiv] [Journal] [80002371 ]
[1.169 ] Family SES Is Associated with the Gut Microbiome in Infants and Children [2021] [Cohort study] [Microorganisms] [Journal] [80002079 ]
[1.170 ]  [2022] [Study] [80002279 ]
[1.171 ] Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis [2022] [Research] [Cells] [Journal] [80002575 ]