Disease ⇒ Thyroid carcinoma {40000409} Record Keys Type:Disease Parent:[ ] Definition:Thyroid carcinoma Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:10066474 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Colorectal cancer] [#Hydrogen sulfide] - H2S at a safe and nontoxic concentration can protect not only healthy cells, such as neurons, but also cancerous cells from apoptosis. - In a variety of cancers, including #Ovarian cancer, #Oral cancer, thyroid cancer, colon cancer, #Breast cancer, etc., the upregulation of H2S-producing enzyme CBS > can enhance the proliferation ability of cancer cells and make cancer cells more sensitive to it [1.2] [1.3] [#Short Chain Fatty Acid] - SCFA, particularly #Butyric acid, inhibits histone deacetylase (HDAC) and activates NIS re-expression in thyroid cancer cells, leading to redifferentiation and enhanced #Iodine uptake References Notes[ ]
