Coriobacteriaceae ⇒ Eggerthella {10000919}

Shared Reference Notes

• [1.1] [#Chronic fatigue syndrome] 
  - MC/CFS > microbiome alterations that were consistent with an increased inflammation of the gut, namely significantly increased #Lactonifactor and #Alistipes - in particular an increase of #Alistipes and a decrease of butyrate-producer #Faecalibacterium were considered as top biomarkers with potential diagnostic value - abundance of #Bifidobacterium and #Faecalibacterium to be reduced in the affected twin compared to the non-affected one. - Decreases in #Faecalibacterium and increases in #Coprobacillus were found. - Gut abundances of #Coprobacillus, of Eggerthella and #Blautia were best able to distinguish patients from controls. - distinct microbial pattern with decreased anti-inflammatory #Firmicutes
• [1.2] 
  - Eggerthella has been consistently found to be increased in #Depression and #Anxiety cases.
• [#Depression] [#Christensenellaceae, #Coprococcus eutactus, #Lachnospiraceae] - RuminococcaceaeUCG005 as the most important genus in predicting depressive symptoms. - #Sellimonas, Eggerthella, #Lachnoclostridium and #Hungatella were more abundant in individuals with higher depressive symptoms. - 12 genera and 1 microbial family associated with depressive symptoms > genera #Sellimonas, Eggerthella, #Ruminococcaceae (UCG002, UCG003, UCG005), #Lachnoclostridium, #Hungatella, Coprococcus, LachnospiraceaeUCG001, Ruminococcusgauvreauiigroup, #Eubacterium ventriosum, #Subdoligranulum and family #Ruminococcaceae.
• - Eggerthella is involved in the synthesis of #Serotonin and gamma aminobutyric acid (#GABA).
• [1.3] [#Bipolar disorder, #Major depressive disorder, #Schizophrenia] 
  - Gut microbiota in BD, MDD and SZ > increase in Eggerthella and #Lactobacillus, together with a decrease in #Coprococcus was common for the three conditions in comparison to controls.
• [1.4] 
  - an increase of #Bifidobacterium and Eggerthella in #Infants who succeeded on at least one of the point and gaze subtests, while having a lower abundance of #Hungatella and #Streptococcus.
• [1.5] [#Prostate cancer] [#Short Chain Fatty Acid] 
  - #Subdoligranulum, #Lachnobacterium, #Christensenellaceae, #Lachnospira, #Rikenellaceae, Eggerthella, and #Alistipes are members of the SCFA-producing order #Clostridiales and were shown to be more prevalent in individuals with high-grade PCA.
• [1.6] [#Major depressive disorder] 
  - An increase in Eggerthella and decrease in #Sutterella were also consistently demonstrated in patients with MDD.
• [1.7] 
  - Eggerthella in humans has been shown to produce #Equol, a #Phytoestrogen, with estrogenic properties and binding affinity to #Estrogen receptors
• [1.8] [#Diabetes Type 2, #Gallstone Disease, #Kidney stone, #Urinary stone disease] 
  - Eggerthella, #Flavonifractor, and #Ruminococcus spp., all of which were enriched in SF, have recently been suggested as general disease-associated signatures (shared across type 2 diabetes, diarrhoea and #Constipation, mental disorders, and gallstones)
• [1.9] [#Clostridium clusters XIVa] 
  - Along with #Bifidobacterium, #Cranberry juice stimulated the growth of #Prevotella, #Clostridium XIVa and Eggerthella, while #Bacteroides was not affected by the #Cranberry juice intake.
• - Eggerthella and #Slackia positively influence host lipid and xenobiotic metabolism.
• [1.11] [#Diabetes Type 2] 
  - #Streptococcus and Eggerthella were relatively more abundant than in prediabetic fecal samples. - #Bacteroides, #Phascolarctobacterium, #Parabacteroides, and #Paraprevotella were more abundant in prediabetic fecal samples.

References Notes