Plant-based diet {51111198}

Shared Reference Notes

• [1.1] [#Ulcerative Colitis] 
  - A positive association between a “high #Sugar and soft drinks” pattern and UC risk - When considering the foods most associated with the pattern, high consumers of #Sugar and soft drinks were at higher UC risk only if they had low vegetables intakes.
• [1.2] [#Biliary tract cancer] 
  - High levels of plant dietary fibers in the gut resulted in proliferation of #Bifidobacterium with anti-inflammatory and anti-tumor effects
• - Intestinal bacteria can turn some plant lignans such as flaxseed, sunflower, caraway, pumpkin, legumes, and soybean, into mammalian lignans with protective effects against #Breast cancer]. - High consumption of raw vegetables showed a significant protective effect against BC risk.
• [#Cancer] - High levels of plant dietary fibers in the gut resulted in proliferation of #Faecalibacterium prausnitzii with anti-inflammatory and anti-tumor effects.
• - Shifting to a plant-based diet would increase #Firmicutes population
• - A plant-based diet stimulates bacterial diversity.
• [1.3] [#Alzheimer’s disease] 
  - Oxidative stress can be modulated by diet, for example, high-fruit-and-vegetable diets improve cognition, which is linked with decreased oxidative stress in elderly;
• [1.4] 
  - Subjects on a vegetable-based diet showed increased abundance of Roseburia, Lachnospira, and Prevotella
• [1.5] [#Short Chain Fatty Acid] 
  - Plant foods and fish > positively associated with short-chain fatty acid-producing commensals and pathways of nutrient metabolism.
• [1.6] [#Plant Microbiome] 
  - several putative short-chain fatty acid (SCFA) fermenters associated with eating more than 30 types of plants, including sOTUs putatively of the species Faecalibacterium prausnitzii and of the genus Oscillospira. - Because bacteria differ in their carbohydrate binding modules and enzymes that hydrolyze diverse substrates in the gut (28), a diet containing various types of dietary fibers and resistant starches likely supports a more diverse microbial community. - Individuals who consume more than 30 types of plants per week compared to those who consume 10 or fewer plants per week had significantly reduced abundance of antibiotic resistance genes for aminoglycosides, chloramphenicol, and major facilitator superfamily (MFS) transporters (antibiotic efflux pumps).
• [1.7] [#Elevated C-reactive protein, #Low high-density lipoprotein cholesterol, #Metabolic syndrome] 
  - Higher long-term PDI (plant-based diet index) was associated with the lower relative abundance of #Peptostreptococcus, while this microbe was positively correlated with the high-sensitivity C-reactive protein and inversely associated with high-density lipoprotein cholesterol.

References Notes