Disease
Microbiota ☳
Metabolome
Factor
Enterobacteriales ⇒ Enterobacteriaceae {10000123}
Record Keys
Parent:
Definition: Enterobacteriaceae
Details
Initialisation date: 2020-09-06
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: [ ]
Notes:
[ ] Shared Reference Notes
[1.1 ] - Members of the Enterobacteriaceae family have a proinflammatory #Lipopolysaccharide (LPS) in the outer membrane and can exacerbate inflammation. A high relative abundance of Enterobacteriaceae is reported in inflammatory bowel diseases, in metabolic disorders like type 2 diabetes, and in immune diseases like cancers.
[1.2 ] [#Biliary tract cancer ] - The predominant dysbiotic bacteria in both #Chronic cholecystitis and gallbladder #Cancer were those belonging to the Enterobacteriaceae family. #Klebsiella increased significantly in the order of normal, #Chronic cholecystitis , and gallbladder #Cancer .
[1.3 ] [#Crohn’s disease ] [#Condition of chronic stress ] - Stress-exposed mice > develop ileal dysbiosis, dominated by the expansion of Enterobacteriaceae .
- Stress-induced glucocorticoids promote > apoptosis of CD45+CD90+ cells that normally produce #IL-22 , a cytokine that is essential for the maintenance of ileal mucosal barrier integrity.
- Blockade of glucocorticoid signaling or administration of recombinant #IL-22 > restores mucosal immunity, prevents ileal dysbiosis.
[1.4 ] [#Depression ] [#Lactobacillaceae , #Limosilactobacillus (Lactobacillus) reuteri ] [#Probiotic (Bifidobacter and Lactobacilus) ] - Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > reduction in depressive symptoms at four and eight weeks of treatment, and #Anxiety symptoms at four weeks.
> improvement in #Sleep quality.
- Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > decrease in serum interleukin-6 levels.
- Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > increased #Bifidobacteriaceae and Lactobacillacea, whereas it decreased Enterobacteriaceae in the gut microbiota composition.
[1.5 ] - #Chronic fatigue syndrome > lower anti-inflammatory species carriage and higher levels of pro-inflammatory bacterial species such as Enterobacteriaceae were found in a 16S rRNA stool sample analysis.
- Higher levels of Enterococcus spp, Streptococcus spp, lower levels of the beneficial Bifidobacteria and decreased anti-inflammatory Firmicutes have been detected.
[1.6 ] [#Infectious diarrhea ] - The gut microbiome undergoes a dramatic taxonomic change upon diarrhea’s onset, favoring the proliferation of fast-growing facultative anaerobes. Proteobacteria (mostly Enterobacteriaceae /E. coli) and Streptococcus (mainly #Streptococcus salivarius and #Streptococcus gallolyticus ) are most significantly enriched during this early phase
[1.7 ] [#Parkinson’s Disease ] - a few putative pathobionts of the family Enterobacteriaceae , #Enterococcaceae , which are assumed to possibly reduce the production of SCFA, produce endotoxins and neurotoxins that promote intestinal inflammation, are enriched in PD
[1.8 ] [#Diabetes Type 1 ] - Particular bacterial protein #BefA , which is found in rodent and human gut microbes, can help restore insulin production
- #BefA -related sequences uncovered homologs in a handful of bacteria of the Enterobacteriaceae family commonly found in healthy mammalian microbiomes after birth, when β cells normally undergo substantial expansion.
- #BefA could induce proliferation directly in primary islet cultures from both hosts (Zebrafish and mouse).
- The #BefA -containing Enterobacteriaceae bacteria are abundant colonizers of the healthy infant gut during peak neonatal β cell expansion.
[1.9 ] [#Parkinson’s Disease ] - positive correlation between Enterobacteriaceae abundance and the motor phenotype, particularly postural instability and gait alterations
[#Antibiotic Therapy , #Infants treated with antibiotic ] - #Infants treated with antibiotics tend to have lower bacterial diversity as well as an increase of Enterobacteriaceae and #Enterococcus
[1.11 ] - alkaline environment of the distant part of the small intestine promotes growth of Enterobacteriacea.
[1.12 ] [#Bipolar disorder ] - Levels of #Faecalibacterium prausnitzii , #Bacteroides –#Prevotella group, #Atopobium Cluster, #Enterobacter spp. and #Clostridium cluster IV were higher in BD patients than healthy subjects along with a reduced #Bifidobacteria to Enterobacteriaceae ratio, having these changes a possible impact on brain function in these patients.
[1.13 ] -#Clostridia and Enterobacteriaceae could also be involved in #Phosphatidylcholine metabolism, which decreases the abundance of #Bifidobacterium spp. due to competition for the substrate.
[1.14 ] [#Short Chain Fatty Acid ] [#Aging ] - Age-related intestinal dysbiosis is generally characterized by a decrease in short-chain fatty acid producers, for example, #Clostridiales , and #Bifidobacterium , and enrichment of pro-inflammatory #Proteobacteria including the opportunistic Enterobacteriaceae .
[1.15 ] - in severe #Depression > reduced #Bifidobacteriaceae and #Prevotellaceae with elevated Enterobacteriaceae and #Ruminococcaceae .
- the level of #Quercetin consumption was negatively correlated with the abundance of #Sutterellaceae and #Oscillospiraceae spp. and positively correlated with the families #Fusobacteriaceae and Enterobacteriaceae
[1.16 ] [#Natural Small intestine Microbiome ] [#Proton pump inhibitors ] - PPI > induce SI duodenal microbiota dysbiosis, characterized by an increase in #Akkermansia muciniphila and #Porphyromonas endodontalis and a decrease in #Enterococcaceae , #Coprococcus , Enterobacteriaceae , and #Synergistes species
[#Natural Small intestine Microbiome ] [#Smoking ] - In the SI lumen, the abundance of #Prevotellaceae , #Neisseriaceae , and #Porphyromonadaceae is reduced in smokers, whereas Enterobacteriaceae and #Lactobacillaceae abundances are increased.
Author: MetaBiom
Identifier: 10000123
URL: https://www.metabiom.org/microbiota/22/enterobacteriaceae
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients [2021] [Research] [mBio] [Journal] [80001737 ]
[1.2 ] Association of Microbial Dysbiosis with Gallbladder Diseases Identified by Bile Microbiome Profiling [2021] [Research] [Journal of Korean Medical Science] [Journal] [80001976 ]
[1.3 ] Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts [2021] [Research] [Nature communications] [Journal] [80002126 ]
[1.4 ] Effects of Probiotic NVP-1704 on Mental Health and Sleep in Healthy Adults: An 8-Week Randomized, Double-Blind, Placebo-Controlled Trial [2021] [Clinical study] [Nutrients] [Journal] [80002236 ]
[1.5 ] The Gut Microbiome in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) [2022] [Review] [Frontiers in Immunology] [Journal] [80002273 ]
[1.6 ] Dynamic of the human gut microbiome under infectious diarrhea [2022] [Study] [Current Opinion in Microbiology] [Journal] [80002290 ]
[1.7 ] Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease [2022] [Review] [Folia Microbiologica] [Journal] [80002403 ]
[1.8 ] From bugs to β cells [2022] [Science] [Journal] [80002472 ]
[1.9 ] Role of the gut microbiota in the development of various neurological diseases [2022] [Review] [NeurologĂa (English Edition)] [Journal] [80002479 ]
[1.10 ] A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration [2022] [Review] [Frontiers in Systems Biology] [Journal] [80002487 ]
[1.11 ] Correlation between human gut microbiome and diseases [2022] [Review] [Infectious Medicine] [Journal] [80002594 ]
[1.12 ] Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities [2023] [Review] [Molecular Psychiatry] [Journal] [80002837 ]
[1.13 ] The role of human milk fats in shaping neonatal development and the early life gut microbiota [2023] [Review] [Microbiome Research Reports] [Journal] [80002843 ]
[1.14 ] How Microbiomes Affect Skin Aging: The Updated Evidence and Current Perspectives [2022] [Review] [Life] [Journal] [80002854 ]
[1.15 ] The Gut Microbiota Links Dietary Polyphenols With Management of Psychiatric Mood Disorders [2019] [Review] [Frontiers in Neuroscience] [Journal] [80002856 ]
[1.16 ] The emerging role of the small intestinal microbiota in human health and disease [2023] [Review] [Gut microbes] [Journal] [80002887 ]
[1.17 ] Inflammatory skin is associated with changes in the skin microbiota composition on the back of severe acne patients [2019] [Experimental Dermatology] [Journal] [80001127 ]
[1.18 ] Bile acid homeostasis and intestinal dysbiosis in alcoholic hepatitis [2018] [Alimentary Pharmacology & Therapeutics] [Journal] [80000969 ]
[1.19 ] Characterization of gut microbiota composition and functions in patients with chronic alcohol overconsumption [2019] [Gut microbes] [Journal] [80001029 ]
[1.20 ] Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort [2019] [Brain, Behavior, and Immunity] [Journal] [80001073 ]
[1.21 ] Microbiota in anorexia nervosa: the triangle between bacterial species, metabolites and psychological tests [2017] [PLOS ONE] [Journal] [80000755 ]
[1.22 ] Sputum microbiota in severe asthma patients: relationship to eosinophilic inflammation [2017] [Respiratory Medicine] [Journal] [80000732 ]
[1.23 ] Helicobacter pylori infection aggravates dysbiosis of gut microbiome in children with gastritis [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001277 ]
[1.24 ] Altered gut microbiota and short chain fatty acids in Chinese children with autism spectrum disorder [2019] [Scientific Reports] [Journal] [80000947 ]
[1.25 ] Characterizing the fecal microbiota of infants with botulism [2015] [Microbiome] [Journal] [80000532 ]
[1.26 ] The microbiota of breast tissue and its association with breast cancer [2016] [Applied and Environmental Microbiology] [Journal] [80000898 ]
[1.27 ] Salivary microbiota and metabolome associated with celiac disease [2014] [Applied and Environmental Microbiology] [Journal] [80000528 ]
[1.28 ] Gut microbiota dysbiosis is associated with altered bile acid metabolism in infantile cholestasis [2019] [mSystems] [Journal] [80001288 ]
[1.29 ] Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome. [2016] [Microbiome] [Journal] [80000273 ]
[1.30 ] Isolation and quantification of uremic toxin precursor-generating gut bacteria in chronic kidney disease patients [2020] [International journal of molecular sciences] [Journal] [80001379 ]
[1.31 ] Microbiome in Chronic Kidney Disease (CKD): An Omics Perspective [2022] [Review] [Toxins] [Journal] [80002388 ]
[1.32 ] Gut microbiome and serum metabolome analyses identify unsaturated fatty acids and butanoate metabolism induced by gut microbiota in patients with chronic spontaneous urticaria [2020] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001363 ]
[1.33 ] Altered profile of human gut microbiome is associated with cirrhosis and its complications [2014] [Journal of Hepatology] [Journal] [80000281 ]
[1.34 ] Gut microbiota composition and Clostridium difficile infection in hospitalized elderly individuals: a metagenomic study [2016] [Scientific Reports] [Journal] [80001033 ]
[1.35 ] Alterations of the predominant fecal microbiota and disruption of the gut mucosal barrier in patients with early-stage colorectal cancer [2020] [BioMed Research International] [Journal] [80001354 ]
[1.36 ] Microbial mucosal colonic shifts associated with the development of colorectal cancer reveal the presence of different bacterial and archaeal biomarkers [2015] [Journal of Gastroenterology] [Journal] [80000707 ]
[1.37 ] Bacterial but not fungal gut microbiota alterations are associated with common variable immunodeficiency (CVID) phenotype [2019] [Frontiers in Immunology] [Journal] [80001137 ]
[1.38 ] Fungal dysbiosis in mucosa-associated microbiota of Crohn’s disease patients [2016] [Journal of Crohn's and Colitis] [Journal] [80000760 ]
[1.39 ] Faecal proteomics: a tool to investigate dysbiosis and inflammation in patients with cystic fibrosis [2016] [Journal of Cystic Fibrosis] [Journal] [80000377 ]
[1.40 ] Comparison of oropharyngeal microbiota from children with asthma and cystic fibrosis [2017] [Mediators of Inflammation] [Journal] [80000734 ]
[1.41 ] Differences in the gut microbiota of healthy children and those with type 1 diabetes [2014] [Pediatrics International] [Journal] [80000885 ]
[1.42 ] Abundance of Enterobacteriaceae in the colon mucosa in diverticular disease [2018] [World Journal of Gastrointestinal Pathophysiology] [Journal] [80000750 ]
[1.43 ] Molecular detection of microbial colonization in cervical mucus of women with and without endometriosis [2019] [American Journal of Reproductive Immunology] [Journal] [80001113 ]
[1.44 ] Alterations to the esophageal microbiome associated with progression from barrett’s esophagus to esophageal adenocarcinoma [2019] [Cancer Epidemiology, Biomarkers & Prevention] [Journal] [80001087 ]
[1.45 ] Association between fecal microbiota and generalized anxiety disorder: severity and early treatment response [2019] [Journal of Affective Disorders] [Journal] [80001071 ]
[1.46 ] Specific gut and salivary microbiota patterns are linked with different cognitive testing strategies in minimal hepatic encephalopathy [2019] [The American Journal of Gastroenterology] [Journal] [80001092 ]
[1.47 ] Intestinal microbiota was assessed in Cirrhotic patients with hepatitis B virus infection [2011] [Microbial Ecology] [Journal] [80000354 ]
[1.48 ] A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. [2014] [PLOS ONE] [Journal] [80000332 ]
[1.49 ] Metagenomic analysis of microbiome in colon tissue from subjects with inflammatory bowel diseases reveals interplay of viruses and bacteria [2015] [Inflammatory Bowel Diseases] [Journal] [80000596 ]
[1.50 ] Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome [2012] [Alimentary Pharmacology and Therapeutics] [Journal] [80000623 ]
[1.51 ] Specific gut microbiome signature predicts the early-stage lung cancer [2020] [Gut microbes] [Journal] [80001413 ]
[1.52 ] Gut Microbiome in Progressive Multiple Sclerosis [2021] [Study] [Annals of Neurology] [Journal] [80002606 ]
[1.53 ] A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease [2019] [Nature communications] [Journal] [80000948 ]
[1.54 ] The microflora associated with human oral carcinomas [1998] [Oral Oncology] [Journal] [80000771 ]
[1.55 ] Gut microbiota dysbiosis worsens the severity of acute pancreatitis in patients and mice. [2019] [Journal of Gastroenterology] [Journal] [80001237 ]
[1.56 ] Short chain fatty acids and gut microbiota differ between patients with Parkinson’s disease and age-matched controls [2016] [Parkinsonism and Related Disorders] [Journal] [80000274 ]
[1.57 ] Pouch inflammation is associated with a decrease in specific bacterial taxa. [2015] [Gastroenterology] [Journal] [80000325 ]
[1.58 ] Gut microbiota dysbiosis in preeclampsia patients in the second and third trimesters [2020] [Chinese Medical Journal] [Journal] [80001375 ]
[1.59 ] Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy [2017] [Gut] [Journal] [80000594 ]
[1.60 ] Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis [2016] [Environmental Microbiology] [Journal] [80000583 ]
[1.61 ] Gut microbiota compositional profile and serum metabolic phenotype in patients with primary open-angle glaucoma [2020] [Experimental Eye Research] [Journal] [80001302 ]
[1.62 ] The bacterial communities of the small intestine and stool in children with short bowel syndrome [2019] [PLOS ONE] [Journal] [80001208 ]
[1.63 ] Dysbiosis of gut microbiota and short-chain fatty acids in acute ischemic stroke and the subsequent risk for poor functional outcomes [2020] [Research] [Journal of Parenteral and Enteral Nutrition] [Journal] [80001423 ]
[1.64 ] Intestinal dysbiosis in inflammatory bowel disease associated with primary immunodeficiency [2019] [The Journal of Allergy and Clinical Immunology] [Journal] [80000914 ]
[1.65 ] Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers [2015] [Gut] [Journal] [80000658 ]
[1.66 ] Defining dysbiosis in patients with urolithiasis_DUBLICATE [2019] [Scientific Reports] [Journal] [80000950 ]
[1.67 ] Subgingival dysbiosis in smoker and non-smoker patients with chronic periodontitis [2017] [Molecular Medicine Reports] [Journal] [80000444 ]
[1.68 ] Sex-specific associations of infants’ gut microbiome with arsenic exposure in a US population [2018] [Scientific Reports] [Journal] [80000820 ]
[1.69 ] Changes of the intestinal microbiota, short chain fatty acids, and fecal pH in patients with colorectal cancer [2013] [Digestive Diseases and Sciences] [Journal] [80000303 ]
[1.70 ] Molecular alteration analysis of human gut microbial composition in Graves’ disease patients [2018] [International Journal of Biological Sciences] [Journal] [80000858 ]
[1.71 ] Characterization of the circulating microbiome in acute-on-chronic liver failure associated with hepatitis B [2019] [Liver International] [Journal] [80001046 ]
[1.72 ] Gut microbial signatures can discriminate unipolar from bipolar depression [2020] [Advanced Science] [Journal] [80001346 ]
[1.73 ] Intestinal microbial ecology in premature infants assessed with non-culture-based techniques [2010] [The Journal of Pediatrics] [Journal] [80001077 ]
[1.74 ] Fecal and blood microbiota profiles and presences of nonalcoholic fatty liver disease in obese versus lean subjects [2019] [PLOS ONE] [Journal] [80001021 ]
[1.75 ] The imbalance of gut microbiota and its correlation with plasma inflammatory cytokines in pemphigus vulgaris patients [2019] [Scandinavian Journal of Immunology] [Journal] [80001162 ]
[1.76 ] The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice [2019] [Science advances] [Journal] [80000888 ]
[1.77 ] Dialister as a microbial marker of disease activity in Spondyloarthritis [2017] [Arthritis & Rheumatology] [Journal] [80000453 ]
[1.78 ] Dysbiosis of the gut microbiome is associated with thyroid cancer and thyroid nodules and correlated with clinical index of thyroid function [2019] [Endocrine] [Journal] [80001043 ]
[1.79 ] The microbiome in urogenital schistosomiasis and induced bladder pathologies [2017] [PLoS Neglected Tropical Diseases] [Journal] [80001012 ]
[1.80 ] Human milk nutrient fortifiers alter the developing gastrointestinal microbiota of very-low-birth-weight infants [2022] [Study] [Cell Host & Microbe] [Journal] [80002552 ]
[1.81 ] Beneficial reconstitution of gut microbiota and control of alpha-synuclein and curli-amyloids-producing enterobacteria, by beta 1,3-1,6 glucans in a clinical pilot study of autism and potentials in neurodegenerative diseases [2021] [Study] [medRXiv] [Journal] [80002371 ]
[1.82 ] Rethinking healthy eating in light of the gut microbiome [2022] [Review] [Cell Host & Microbe] [Journal] [80002441 ]
[1.83 ] Oral Microbiome: Getting to Know and Befriend Neighbors, a Biological Approach [2022] [Review] [biomedicines] [Journal] [80002370 ]