Disease ⇒ Posttreatment Lyme disease syndrome {40000527} Record Keys Type:Disease Parent:[ ] Definition:Posttreatment Lyme disease syndrome Details Initialisation date:2021-03-31 Other Terms:PTLDS Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:Infectiology Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - Patients with PTLDS have significantly elevated expression of interferon alpha, greater antibody reactivity to brain antigens, increased levels of the chemokine CCL19 and the cytokine interleukin 23 (IL-23), and a decrease in the CD57 lymphocyte subset. [#Antibiotic Therapy] - While antibiotics likely affect the microbiome, our results suggest that antibiotic influence alone cannot explain the distinctive microbiomes of PTLDS patients. - #Blautia species represented three of the five most important features for this classification, and the relative abundance was elevated in the PTLDS cohort compared to those in the healthy and ICU cohorts.References Notes[ ]
