Lachnospiraceae ⇒ Coprococcus {10000174}

Shared Reference Notes

• [1.1] 
  - #Protein powder consumption > decrease in #Lachnospiraceae, #Roseburia, #Blautia, Synergistales, Coprococcus, #Lactobacillales, Bacilli, #Bifidobacterium longum and #Firmicutes. - #Protein powder consumption > higher abundance of #Bacteroidetes.
• [1.2] 
  - Members of the genera #Oscillospira and Coprococcus in the cecum, as well as #Faecalibacterium prausnitzii and members of the genus #Bacteroides in the ileum > negatively correlated with #Fibrosis.
• [1.3] [#Diabetes Type 2] [#Coprococcus etes] 
  - There are 36 different strains of #Butyrate-producing bacteria, and five of them are associated with increased insulin sensitivity: Coprococcus etes, #Oscillibacter sp. CAG 241, #Alistipes finegoldi and #Faecalibacterium prausnitzii. - The genus Coprococcus was associated with higher insulin sensitivity and disposition index and a lower rate of dysglycemia.
• [1.4] [#Crohn’s disease] [#Clostridium cluster IV] 
  - #Roseburia, #Gemmiger, Coprococcus, #Ruminococcus 2, #Butyricicoccus, #Dorea, #Fusicatenibacter, #Anaerostipes, Clostridium IV were enriched in the healthy controls. - #Blautia, Clostridium IV, Coprococcus, #Dorea, #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase. - negative correlation between #Dorea, #Butyricicoccus, #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR . - positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms.
• [1.5] [#Diabetes Type 2] 
  - A reduction in the #Lachnospira, #Roseburia, #Faecalibacterium and Coprococcus genera in the T2D group. - These genera were #Butyrate producers. - The decrease of these genera favored #Obesity and the development of diseases.
• [1.6] 
  - #Subdoligranulum and Coprococcus were consistently found to be depleted in individuals with generalized #Anxiety disorder and #Depression
• - Both #Subdoligranulum and Coprococcus are involved in the production of #Butyrate
• [1.7] [#Bipolar disorder, #Major depressive disorder, #Schizophrenia] 
  - Gut microbiota in BD, MDD and SZ > increase in #Eggerthella and #Lactobacillus, together with a decrease in Coprococcus was common for the three conditions in comparison to controls.
• [1.8] [#Natural Small intestine Microbiome] [#Proton pump inhibitors] 
  - PPI > induce SI duodenal microbiota dysbiosis, characterized by an increase in #Akkermansia muciniphila and #Porphyromonas endodontalis and a decrease in #Enterococcaceae, Coprococcus, #Enterobacteriaceae, and #Synergistes species
• [1.9] [#Behcet’s Disease] 
  - Depleted #Dorea, #Blautia, Coprococcus, #Erysipelotrichaceae and #Lachnospiraceae as well as enriched #Bilophila and #Stenotrophomonas were identified in BU patients.
• [#Obesity] [#Collinsella aerofaciens] - subjects with BMI values ≥25 kg/m2 have higher relative abundances of members of the #Collinsella genus (e.g., #Collinsella aerofaciens), and the #Veillonellaceae and #Lachnospiraceae families (e.g., genera #Dorea, #Lachnospira, Coprococcus).
• [#Obesity] - Coprococcus abundance correlates positively with level of subcutaneous body fat.
• [#Obesity] - Coprococcus genus and #Lachnospiraceae, were more abundant in subjects with BMI ≥25 kg/m2 and those with greater skeletal muscle mass
• [1.11] 
  - In patients with #Psoriatic Arthritis, there was a decrease in the abundance of certain bacteria such as #Akkermansia, #Ruminococcus, #Pseudobotyrivibrio, #Paraacteroides, #Alistipes, and Coprococcus
• [1.12] [#Omega 3] 
  - omega-3 rich diet has been shown to result in a significant increase in #Subdoligranulum, along with other #Butyrate producers like #Anaerostipes, Coprococcus, and #Roseburia.
• [#Juvenile idiopathic arthritis] - ABIS JIA had higher abundance of #Acidaminococcales, #Prevotella 9, and #Veillonella parvula and lower abundance of Coprococcus, #Subdoligranulum, #Phascolarctobacterium, #Dialister spp., #Bifidobacterium breve, #Fusicatenibacter saccharivorans, #Roseburia intestinalis, and #Akkermansia muciniphila
• [1.13] [#Fasting] 
  - RIF was associated with significant drops in the levels of seven genera at the end of Ramadan: #Blautia, Coprococcus, #Dorea, #Faecalicatena, #Fusicatenibacter, #Lachnoclostridium, and #Mediterraneibacter.
• [#Fasting] - Coprococcus produce #Butyrate. - genera Coprococcus significantly decreased after RIF. - Coprococcus experienced a decrease during starvation, but later on, they increased during the refeeding
• [#Keto diet] - Coprococcus abundance was decreased in subjects who were fed a ketogenic diet
• [#Meat-based diet] - a strict #Vegan diet led to an increase in Coprococcus levels, while a meat-rich diet (>150 g of meat per day) resulted in a decrease
• [#Obesity] - individuals with an overweight phenotype have increased levels of specific bacterial genera in the #Firmicutes phylum, including #Blautia, Coprococcus, and #Dorea
• [1.14] 
  - Coprococcus has consistently demonstrated a low abundance in intestinal, neuropsychological, and neurodegenerative disorders
• [#Omega 3, #β-Galacto-oligosaccharides] [#High fibre diet] - Coprococcus abundance can be rapidly increased by fibre, galacto-oligosaccharides, or omega-3 fats supplementation, as well as by #Probiotic administration
• - #Depression > depletion of Coprococcus
• [#Parkinson’s Disease] [#Coprococcus catus, #Coprococcus comes] - all Coprococcus members produce #Butyrate or via independent mechanisms, such as the potential of C. catus and C. comes to synthesise #DOPAC, a metabolite implicated in PD.
• [#Parkinson’s Disease] [#Coprococcus eutactus] - specific correlations between C. eutactus and PD and between C. eutactus and language development were found, whereas most studies reported associations between the Coprococcus genus.
• [1.15] 
  - Reduced abundance of the genus Coprococcus in #Alzheimer’s disease, which is associated with #Amyloid accumulation.
• [1.16] [#Bacteroides-Prevotella group, #Ruminococcus gauvreauii] 
  - marked reduction in #Butyrate-producing bacterial genera, such as Coprococcus, and #Subdoligranulum, in both the ileum and colon; #Faecalibacterium in colon; and [#Ruminococcus] gauvreauii group in fecal samples from People living with HIV (PLWH)
• - #Erysipelotrichaceae UCG-003, Coprococcus, #Faecalibacterium, and #Subdoligranulum, significantly lower in PLWH and were associated with slower rates of biological #Aging.
• [1.17] [#Gout] 
  - Altered compositions of microbiota, characterized by a reduced abundance of genus Coprococcus, were found in subjects with #Hyperuricemia compared with those with normouricemia.
• [1.18] 
  - #Gout > Coprococcus 3 was causally associated with a higher #Gout risk.
• [1.19] [#Autism] 
  - In ABIS, #Infants who had otitis in their first year were found to be more prone to acquiring NDs if they lacked detectable levels of Coprococcus or harbored #Citrobacter.
• [#Antibiotic Therapy, #Infants] - Coprococcus has potent anti-inflammatory properties and, in ABIS, was inversely associated with NDs and linked to protective factors, including lower vulnerability scores, fewer antibiotics (none in the first year), and infant diets with fewer snacks.
• [#Depression] - Species of Coprococcus, #Akkermansia, #Roseburia, and #Turicibacter were inversely associated with mood symptoms at age 5.
• [#COPD Exacerbation] - In COPD > the relative abundance of #Lachnospira and Coprococcus was negatively related to the #Smoking index and positively related to lung function results. - The relative abundance of #Parabacteroides was positively correlated with the #Smoking index and negatively correlated with lung function findings.
• [1.21] [#Schizophrenia] 
  - Megasphera, #Akkermansia, #Fusobacterium and #Prevotella were significantly more abundant in SCZ patients, and #Citrobacter, #Blautia, Coprococcus, #Lachnoclostridium were more abundant in HC controls.
• [#Schizophrenia] [#Ruminococcus] - #Shigella and #Collinsella were more abundant in SCZ patients, and #Faecalibacterium, Coprococcus, #Prevotella, #Haemophilus, Ruminococcaceae_Ruminococcus, #Bacteroides, and #Oscillospira are significantly abundant in HC
• [1.22] [#High fibre diet] 
  - dietary fiber enriches Coprococcus. - Coprococcus has been shown to contribute to the production of #Butyrate
• [1.23] 
  - Researchers identified two bacterial genera Coprococcus and #Dialister were depleted in patients with #Depression whether or not they were taking antidepressants.

References Notes