Treponema ⇒ Clostridium cluster IV {10000878} Record Keys Parent:Treponema Definition:Clostridium cluster IV Details Initialisation date:2021-01-13 Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:Chlosterol dehydrogenase Function:Lipid metabolism, Anti-cholesterolemia Notes: [ ]Shared Reference Notes [1.1] [#Crohn’s disease] - #Roseburia, #Gemmiger, #Coprococcus, #Ruminococcus 2, #Butyricicoccus, #Dorea, #Fusicatenibacter, #Anaerostipes, Clostridium IV were enriched in the healthy controls. - #Blautia, Clostridium IV, #Coprococcus, #Dorea, #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase. - negative correlation between #Dorea, #Butyricicoccus, #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR . - positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms. [1.2] [#Bipolar disorder] - Levels of #Faecalibacterium prausnitzii, #Bacteroides–#Prevotella group, #Atopobium Cluster, #Enterobacter spp. and Clostridium Cluster IV were higher in BD patients than healthy subjects along with a reduced #Bifidobacteria to #Enterobacteriaceae ratio, having these changes a possible impact on brain function in these patients. [1.3] - TNF-α was found to be positively correlated with the abundance of #Parabacteroides, #Bilophila, and #Clostridium IV, but negatively correlated with the abundance of #Prevotella. [1.4] [#Clostridiales XIV] - #Walnut consumption at 42 g/day, increased #Butyrate-producing #Clostridium clusters XIV and IV including, #Faecalibacterium, #Roseburia, while lowering the relative abundance of #Ruminococcus, #Dorea, Oscilllo, #Bifidobacteria. [1.5] [#Clostridium clusters XIVa] [#Butyrate] - The predominant butyrogenic bacterial species, including #Faecalibacterium prausnitzii, #Clostridium spp., #Eubacterium spp., and #Roseburia spp., are from two clusters (#Clostridium clusters IV and XIVa) in the #Firmicutes phylum and the #Clostridiales order [1.6] - the species showing strong correlations with steroid hormone biosynthesis, including #Alistipes, #Clostridium IV and #Tannerella, might contribute to the transformation of steroidal hormones by their metabolic products.References Notes[ ]