Posibacteria ⇒ Actinobacteria {10000199} Record Keys Parent:Posibacteria Definition:Actinobacteria Details Initialisation date:2019-05-12 LinksSource Meta Information Rank: Phylum Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Cutibacterium acnes, #Staphylococcus epidermidis] - #Acne > increased Actinobacteria followed by #Firmicutes and #Proteobacteria, #Cutibacterium,#Staphylococcus and #Corynebacterium. - C. acnes > major species in terms of mean abundance, followed by #Staphylococcus epidermidis (S. epidermidis) and #Staphylococcus hominis (S. hominis); [1.2] - The number of isolated Actinobacteria decreased immediately after eradication therapy and returned to pretreatment condition at the eradication judgment point. There was no change in the relative abundance at genus level [1.3] [#Consuming resistant potato starch, #Resistant starch] - Lower intake of RS > increased relative abundance of actinobacteria [1.4] [#Diabetes Type 2] - #Black women, regardless of insulin sensitivity > greater relative abundance of the phylum Actinobacteria, compared to White women. - #Black women with insulin resistance > four fold higher #Verrucomicrobia abundance than White women. [1.5] [#Major depressive disorder] - Actinobacteria were found to be increased, whereas #Bacteroidetes were decreased in relation to other phyla, and some studies suggested decreased microbial diversity in MDD patients [1.6] [#Natural ear microbiota] - The microbiota of the ear canal is similar to that found on the skin. Therefore, #Corynebacterium, #Staphylococcus, and #Propionibacterium genera are prevalent taxa. - middle ear is actually colonized by Proteobacteria, Actinobacteria, and #Firmicutes [1.7] [#Peptic ulcer] [#Antibiotic Therapy] - The population of Actinobacteria is decreased by the use of #Helicobacter pylori treatment. [1.8] [#Fecal Microbiota Transplantation] - recipients with higher donor strain engraftment were more likely to experience clinical success after FMT. - #Bacteroidetes and Actinobacteria species (including Bifidobacteria) displayed higher engraftment than #Firmicutes except for six under-characterized #Firmicutes species. [1.9] - #Proanthocyanidins are biotransformed by #Adlercreutzia equolifaciens JCM 14793T, #Eubacterium sp. SDG-2, #Eggerthella lenta rK3 and #Eggerthella lenta CAT-1 and from the phylum actinomycetes, which belong to the phylum Actinobacteria, through the cleavage of the C-ring and dihydroxylation reactions to produce (−)EGC, (−)-gallocatechin (GC), (±)EC and (±)-catechin (C) [#Graves’ disease, #Graves’ orbitopathy] - when patients were hyperthyroid and TRAB positive, Actinobacteria were significantly increased and Bacteroidetes significantly decreased in GD/GO compared with HC. - #Bacteroides displayed positive and negative correlations with TSH and FT4 respectively and was also significantly associated with #Smoking in GO, #Smoking is a risk factor for GO but not GD. [1.11] [#Alzheimer’s disease] - AD > A positive correlation between the pro-inflammatory cytokines and Escherichia/Shigella (pro-inflammatory taxon) and a negative correlation with #Eubacterium rectale (anti-inflammatory taxon). - a decrease in #Firmicutes and #Bifidobacterium and increased levels of #Proteobacteria, Actinobacteria - a disputed frequency of #Bacteroidetes in various studies.. [1.12] [#Natural Skin Microbiome] [#Infants] - Infant skin > 21 bacterial phyla with #Proteobacteria, #Firmicutes, Actinobacteria, and #Bacteroidetes being the most abundant. - the relative abundance of #Burkholderiaceae and #Staphylococcus, highly abundant after birth, decreased progressively, to the benefit of newly colonizing taxa such as #Streptococcus, #Veillonella, and #Enhydrobacter aerosaccus [1.13] - Five bacterial phyla including #Firmicutes, #Bacteroidetes, Actinobacteria, #Proteobacteria, and #Fusobacteria can participate in #Tryptophan metabolism, being those belonging to the #Clostridium, #Burkholderia, #Streptomyces, #Pseudomonas or #Bacillus genera the most important modulators [#Bipolar disorder] - BD patients with a depressive episode > increased levels of #Coriobacteria and Actinobacteria together with decreased #Ruminococcaceae and #Faecalibacterium. [1.14] [#Gender] - #Depression > Female patients have a characteristic increase in the phyla Actinobacteria, male patients have reduced #Bacteroidetes and both genders display disrupted #Firmicutes homeostasis and elevated #Collinsella spp. abundance [1.15] - #Anorexia nervosa > lowered Actinobacteriota and #Bacteroidota counts. - Among families of bacteria, #Christensenellaceae species, particularly CAG-138, showed the most significant enrichment in AN. [1.16] [#Obesity] [#Physical activity] - In normal but not overweight participants, high PA duration showed greater relative abundance of commensal taxa such as Actinobacteria and #Proteobacteria phyla, as well as #Collinsella and #Prevotella genera. [1.17] [#Natural Small intestine Microbiome] - The SI microbiota is composed primarily of facultative anaerobic and aerobic bacteria, in particular, belonging to the phyla #Firmicutes, #Proteobacteria and Actinobacteria. [1.18] - In acute #Colitis, #Melatonin led to increased clinical, systemic and intestinal inflammatory parameters. - During remission, continued MLT administration delayed recovery, increased TNF, memory effector lymphocytes and diminished spleen regulatory cells. - MLT treatment reduced #Bacteroidetes and augmented Actinobacteria and #Verrucomicrobia phyla in mice feces. - Microbiota depletion resulted in a remarkable reversion of the #Colitis phenotype after MLT administration, including a counter-regulatory immune response, reduction in TNF and colon macrophages. - There was a decrease in Actinobacteria, #Firmicutes and, most strikingly, #Verrucomicrobia phylum in recovering mice. Finally, these results pointed to a gut-microbiota-dependent effect of MLT in the potentiation of intestinal inflammation. [1.19] - The Actinobacteria phylum includes pathogens (species of #Corynebacterium, #Mycobacterium, #Nocardia, and #Propionibacterium), #Soil inhabitants (Micromonospora and #Streptomyces species), plant commensals (Frankia spp.), and GI commensals (#Bifidobacterium spp.) [#Gastric carcinoma] - Gastric mucosal biopsies from intra-epithelial neoplasia and adenocarcinoma patients have shown a higher abundance of Actinobacteria, #Bacteroides, #Firmicutes, and #Fusobacteria [1.21] - protective role against #Female infertility, > #Ruminococcus, #Desulfovibrio. #Bifidobacteriales, #Bifidobacterium, Actinobacteria, #Ruminococcaceae NK4A214, #Bifidobacteriaceae, Actinobacteria, #Holdemania. [1.22] [#Systemic lupus erythematosus] - Actinobacteria, #Bacillales, #Coprobacter and #Lachnospira were inversely correlated with the risk of SLE, and #Bacilli, Eggertella and #Lactobacillales might be the risk factors of SLE. [1.23] - Celiac > microbiota is abundant with pro-inflammatory Gram-negative species, such as #Proteobacteria, Bacterioides, #Prevotella, ecc., while it is poor in probiotic ones, such as #Firmicutes, Actinobacteria, #Bifidobacteria, #Lactobacilli, and Streptococceae, which have instead a protective rol [1.24] [#Natural Skin Microbiome] - #Firmicutes, #Proteobacteria, and Actinobacteria as the primary active microbial phyla in Chamliyal #Clay. - These resemble those abundant in a healthy human skin microbiome. - This is significant as lower levels of these phyla in the skin are linked to inflammatory skin conditions like #Psoriasis. [1.25] - #Bacteroides fragilis and #Prevotella copri (#Bacteroidetes), #Bifidobacterium longum and #Collinsella aerofaciens (Actinobacteria), and #Helicobacter pylori (#Proteobacteria) can produce #Vitamin B6 as they have these biosynthetic mechanisms - Enhanced #Pantothenic acid intake increased the relative abundance of #Prevotella and Actinobacteria and decreased the abundance of #Bacteroides in lactating women [1.26] [#Fructooligosaccharides, #humanized Galactooligosaccharides] - Actinobacteria, #Bacteroidetes, and #Firmicutes, can ferment FOS, GOS, and xylooligosaccharides (XOS). [1.27] [#Estrogen] - women with low estradiol were significantly enriched of Actinobacteria and #Bacteroidetes, [#Major depressive disorder] [#Gender] - Women with MDD display higher levels of Actinobacteria compared to healthy women, whereas men with MDD exhibited lower levels of #Bacteroidetes. [1.28] [#Gastric bypass surgery] - Roux-en-Y gastric bypass (RYGB) resulted in clear alteration in composition of gut fungal and bacterial microbiota. - Before surgery, patients had higher levels of #Firmicutes and Actinobacteria and lower levels of #Verrucomicrobia - #Faecalibacterium and #Bifidobacterium showed a decrease after surgery and aerotolerant #Streptococcus was increased postoperatively. - The relative abundance of #Proteobacteria was increased after surgery. - Changes in fungal microbiota composition included decreases in #Candida and #Saccharomyces and increases in #Pichia. - levels of #Verrucomicrobia and #Proteobacteria increased after the surgery procedure - Bifidobacteriaceae abundance decreased, whereas Streptococcaceae and Enterobacteriaceae increased after surgery. - RYGB led to increased #Firmicutes and Actinobacteria phyla but decreased #Bacteroidetes phylum [1.29] - in adults > decreased abundance of bacteria from the phylum Actinobacteria and increased abundance of bacteria from the phylum #Bacteroidetes in those tested early in the #Pandemic compared to before the #Pandemic. [#Breast cancer] - live bacteria from three main phyla—#Proteobacteria, #Firmicutes, and Actinobacteria—can be found in breast tumors. [1.31] [#Natural Nose microbiome] - #Firmicutes and #Proteobacteria are abundantly present in #Children, whereas Actinobacteria are over-represented in adults. [1.32] - enrichment of Actinobacteria in patients with #Ankylosing spondylitis, and depletion of #Fusobacteria and #Verrucomicrobia - Patients with #Primary biliary cirrhosis were found to show enrichment of Actinobacteria, #Lactobacillales, #Streptococcus, #Klebsiella and #Veillonella [1.33] [#Natural Skin Microbiome] - Belly button (BB) and between toes (BT) (moist microenvironment) were mainly comprised of Actinobacteriota and #Firmicutes; behind ears (BE) (oily microenvironment) was dominated by #Firmicutes; and calves (CA) and forearms (FA) (dry microenvironment) included a combination of those three phyla. - BB and BT (moist microenvironment) were dominated by #Staphylococcus and #Corynebacterium, BE (oily microenvironment) by #Staphylococcus and #Anaerococcus, while CA and FA (dry microenvironment) showed a high proportion of #Staphylococcus and #Corynebacterium, but also of #Streptococcus and #Escherichia-#Shigella. #Anaerococcus was also highly abundant in BB. [1.34] - conjunctival swabs from Bacterial #Keratitis patients contained significantly less Actinobacteria and #Corynebacteria (determinate beneficial symbiotic #Bacteria), but significantly more #Gammaproteobacteria, #Pseudomonas, #Bacteroides, and EscherichiaShigella (common ocular pathogenic #Bacteria). [1.35] - increased abundance of the phylum Actinobacteria in #Gout patients - the abundance of phylum Actinobacteria is negatively correlated with SUA levels. [#Gout] - elevated SUA levels can also increase the abundance of phylum Actinobacteria, suggesting a potential negative feedback and regulatory mechanism between phylum Actinobacteria and SUA levels. [1.36] [#Rheumatoid Arthritis] - Actinobacteria, as a pathogen closely related to RA, may be an important factor that directly induces RA in damp environments [#Rheumatoid Arthritis] - #Deltaproteobacteria, #Bacteroidaceae, and Actinobacteria were the most common bacteria in #High humidity intervention healthy rats. [1.37] - Actinobacteria, also known as Actinomycetes , are commonly found in the oral cavity and are dysbiotic gastrointestinal microbiota [1.38] [#Polycystic ovary syndrome] - Women suffering from PCOS had increased levels of #Fusobacterium and decreased levels of Actinobacteria in their salivary microbiomes [1.39] [#Moyamoya disease] - The relative abundance of #Fusobacteriota/Actinobacteria was significantly higher/lower in the MMD group than that in the HC group. [#Obstructive sleep apnea-hypopnea syndrome] [#GABA] - Actinobacteria were significantly downregulated in OSA. - Actinobacteria are renowned for producing the #Sleep-inducing neurotransmitter gamma-aminobutyric acid. - a negative correlation was observed between Actinobacteria and the number of awakenings in healthy individuals [1.41] [#Grade of Crow’s feet wrinkles] - Bacteria associated with low GCFW, including taxa from the two major skin phyla #Firmicutes and Actinobacteria > include Staphylococcus (taxon classified as #Staphylococcus equorum) as well as #Kocuria, #Peptostreptococcus, and #Lysobacter, which have been shown to be both skin and environment-related taxa. [1.42] [#Cushing’s disease] - #Collinsella, a genus form of the Actinobacteria phylum was present in CD patients only, whereas #Sutterella, a genus from #Proteobacteria phylum, was scarcely detectable/undetectable in CD patients as well as #Lachnospira, a genus of the #Lachnospiraceae family of the #Firmicutes phylum.References Notes[ ]