Thermodesulfobiaceae ⇒ Cutibacterium {10001989} Record Keys Parent:Thermodesulfobiaceae Definition:Cutibacterium Details Initialisation date:[ ] Meta Information Rank: Genus Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Cutibacterium acnes, #Staphylococcus epidermidis] - #Acne > increased #Actinobacteria followed by #Firmicutes and #Proteobacteria, Cutibacterium,#Staphylococcus and #Corynebacterium. - C. acnes > major species in terms of mean abundance, followed by #Staphylococcus epidermidis (S. epidermidis) and #Staphylococcus hominis (S. hominis); [1.2] [#Allergy] - Cutibacterium > ferments hexoses > Embden–Meyerhof pathway > produce #Pyruvate > metabolized into propionate > reduce antigen presentation on dendritic cells as > GPR41-dependent modulation of hematopoiesis and affected allergic diseases in a mouse model [1.3] [#Natural Skin Microbiome] - Members of the genus Cutibacterium (previously known as #Propionibacterium), dominate the sebaceous (oily) sites of the human skin. [1.4] - #Kocuria and Cutibacterium were enriched in healthy subjects, while #Staphylococcus was enriched in psoriatic disease. - The relative abundance of #Corynebacterium was higher in NL #Psoriatic Arthritis (PsA). samples compared with NL #Psoriasis (PsO) samples. [1.5] [#Natural Skin Microbiome] [#Aging] - At the genus level, old-aged skin exhibited an increase in #Corynebacterium and a decrease in Cutibacterium relative abundance [#Natural Skin Microbiome] - #Aging > Cutibacterium decreased in the cheeks, forehead, and forearms [1.6] [#Cutibacterium acnes] - Cutibacterium acnes secretes a thiopeptide RiPP called #Cutimycin that inhibits members of #Staphylococcus but does not affect the members of the genera #Corynebacterium and Cutibacterium. -RiPPs from #Lactobacilli have shown to inhibit members of #Staphylococci, Cutibacterium and #Corynebacterium [1.7] [#Skin aging] [#Cutibacterium acnes] - C. acnes was likely responsible for the #Aging-related depletion of Cutibacterium [1.8] - Individuals with high levels of #Bacteroides in the stool also have high Cutibacterium on the skin and #Prevotella in the oral microbiome. - The correlated #Bacteroides in the stool and Cutibacterium in the skin are both closely related to lipid metabolism [1.9] [#Aging] - microbial diversity on cheek skin was higher in older individuals than in younger adults, and that Cutibacterium trended lower in older individuals. - microbial diversity tended to decrease with decreasing skin barrier function.References Notes[ ]
