Thermodesulfobiaceae ⇒ Cutibacterium {10001989}

Shared Reference Notes

• [1.1] [#Cutibacterium acnes, #Staphylococcus epidermidis] 
  - #Acne > increased #Actinobacteria followed by #Firmicutes and #Proteobacteria, Cutibacterium,#Staphylococcus and #Corynebacterium. - C. acnes > major species in terms of mean abundance, followed by #Staphylococcus epidermidis (S. epidermidis) and #Staphylococcus hominis (S. hominis);
• [1.2] [#Allergy] 
  - Cutibacterium > ferments hexoses > Embden–Meyerhof pathway > produce #Pyruvate > metabolized into propionate > reduce antigen presentation on dendritic cells as > GPR41-dependent modulation of hematopoiesis and affected allergic diseases in a mouse model
• [1.3] [#Natural Skin Microbiome] 
  - Members of the genus Cutibacterium (previously known as #Propionibacterium), dominate the sebaceous (oily) sites of the human skin.
• [1.4] 
  - #Kocuria and Cutibacterium were enriched in healthy subjects, while #Staphylococcus was enriched in psoriatic disease. - The relative abundance of #Corynebacterium was higher in NL #Psoriatic Arthritis (PsA). samples compared with NL #Psoriasis (PsO) samples.
• [1.5] [#Natural Skin Microbiome] [#Aging] 
  - At the genus level, old-aged skin exhibited an increase in #Corynebacterium and a decrease in Cutibacterium relative abundance
• [#Natural Skin Microbiome] - #Aging > Cutibacterium decreased in the cheeks, forehead, and forearms
• [1.6] [#Cutibacterium acnes] 
  - Cutibacterium acnes secretes a thiopeptide RiPP called #Cutimycin that inhibits members of #Staphylococcus but does not affect the members of the genera #Corynebacterium and Cutibacterium.
• -RiPPs from #Lactobacilli have shown to inhibit members of #Staphylococci, Cutibacterium and #Corynebacterium
• [1.7] [#Skin aging] [#Cutibacterium acnes] 
  - C. acnes was likely responsible for the #Aging-related depletion of Cutibacterium

References Notes