Veillonellaceae ⇒ Megamonas {10000725}

Shared Reference Notes

• [1.1] [#Hereditary angioedema attacks] 
  - Presence of Megamonas was a strong marker among patients with recent Hereditary angioedema episodes. - Absence of Roseburia species was significantly associated with long-term occurrence of gastrointestinal angioedema. - The mean abundance of some Proteobacteria, including Morganella, Pantoea, and Klebsiella species, was considerably increasedamong individuals with frequent gastrointestinal angioedema. - patients with frequent laryngeal edema > decreased Aeromonas , Vibrio , Aquabacterium , Wolinella , Rikenella , and Solibacillus abundance as well as increased Advenella abundance . - Decreased Proteobacteria abundance was observed among patients with HAE taking danazol or tranexamic acid
• [1.2] 
  - At the genus level, #Prevotella and #Bacteroides were significantly enriched in the #Meditation group. - Two beneficial bacterial genera (Megamonas and #Faecalibacterium) were significantly enriched in the #Meditation group. - Several pathways—including glycan biosynthesis, metabolism and lipopolysaccharide biosynthesis—were significantly enriched in the #Meditation group. - Plasma levels of clinical risk factors were significantly decreased in the #Meditation group, including total #Cholesterol and apolipoprotein B.
• [1.3] [#Bacteroides-Prevotella group] 
  - only #Faecalibacterium, but not #Blautia, #Anaerostipes, or Megamonas, was significantly lower in the #Hypertension group
• [#Lipopolysaccharide, #Short Chain Fatty Acid] - #Hypertension groups > low gut microbial diversity and some distinctive taxa, depleted SCFA-producing bacteria, such as Ruminococcacea and #Faecalibacterium, and enriched LPS-producing gram-negative bacteria, such as #Bacteroidales, #Negativiticus, and Megamonas,
• [1.4] 
  - Other genera in the #Bacteroidetes phyla are #Alistipes, #Anaerorhabdus, #Dichelobacter, #Fibrobacter, Megamonas, #Mitsuokella, #Rikenella, #Sebaldella, #Tannerella, and #Tissierella.
• [1.5] 
  - The family #Selenomonadaceae, which has the characteristics of strictly anaerobic and gram-negative #Bacilli, was first classified as a new family within the order #Selenomonadales in the class #Negativicutes in 2015. The family currently contains 43 species in 8 genera, including #Anaerovibrio, #Centipeda, Megamonas, #Mitsuokella, #Pectinatus, #Propionispira, #Schwartzia, and #Selenomonas.
• [1.6] 
  - Megomonas has been isolated from human and animal intestines, a study showed it may play a protective role in #Glaucoma and #Keratitis. - There was a positive correlation between decreased #Citric acid and Megamonas. - It was proven that the #Citric acid cycle plays a pivotal role in regulating energy homeostasis and cell metabolism, which is correlated with the mitochondrial dysfunction of glaucom.
• - the bacterial #Keratitis group had a significantly higher abundance of #Bacillus and Megamonas.
• [1.7] [#Autism] 
  - #Gluconobacter, Pseuodomonas, Kroppenstedtia, #Acinetobacter and Megamonas were only present in feces from the GP #Children in despite to ASD #Children

References Notes