Disease ⇒ Cancer ⇒ Lung cancer {40000372}

Shared Reference Notes

• [1.1] 
  - A greater abundance of Spirochaetia was associated with lower risk of cancer, and increased levels of Lactobacillales was linked to a heightened risk
• [1.2] 
  - Veillonella, Megasphaera, and Streptococcus > increased in lung cancer patients. - Neisseria, Staphylococcus, and Dialister > higher level in lung cancerous lesions than in normal lung tissues
• [1.3] [#Asthma, #Cystic fibrosis, #Pneumonia] 
• [1.4] 
  - every standard deviation increase in #Streptococcus abundance was associated with 1.14 times the risk of lung cancer
• [1.5] [#kynurenine, #Tryptophan] 
  - A high-serum Kyn/Trp ratio is also correlated with a poor prognosis after a PD-1 blockade in lung cancer, #Melanoma and #renal cell carcinomas
• [1.6] 
  - In lung cancer, #Blastomyces was associated with tumor tissues.
• [1.7] [#Streptococcus agalactiae, #Streptococcus salivarius] 
  - For non-small cell lung cancer patients, S. salivarius and S. agalactiae react upon gastrointestinal-derived CD4+ T cells and effectively activate monocytes to secrete higher levels of #IL-6, IL-12 and TNF, or so-called, the Th1- and Th17-skewed cytokines
• [1.8] [#Colorectal cancer, #Pancreatic Cancer] [#Veillonella atypica] 
  - #Veillonella genus is usually more abundant in treatment-naïve patients with lung, pancreatic (#Veillonella atypica) and colorectal #Cancer. - Furthermore, when comparing patients with advanced-stage #Cancer with and without weight loss, #Veillonella is more abundant in those who lost weight.
• [1.9] [#Fermented food] 
  - Fermented dairy intake was inversely associated with lung cancer risk
• [#Colorectal cancer, #Pancreatic Cancer] [#Veillonella atypica] - #Veillonella genus is usually more abundant in treatment-naïve patients with lung, pancreatic (#Veillonella atypica) and colorectal #Cancer.
• [1.11] 
  - Oral bacteria from genera #Capnocytophaga and #Veillonella are reportedly present in increased amounts in lung cancer patients
• [1.12] [#Smoking] 
  - most of the enriched taxa in the lung tumors of smokers belong to the #Proteobacteria phylum
• [#Smoking] - MetaCyc pathways responsible for the degradation of chemicals in cigarette smoke, such as toluene, acrylonitrile, and aminobenzoates, were significantly enriched in bacteria found in lung tumors compared with other tumor types

References Notes