Paenibacillaceae ⇒ Fusicatenibacter {10001324}

Shared Reference Notes

• [1.1] [#Crohn’s disease] [#Clostridium cluster IV] 
  - #Roseburia, #Gemmiger, #Coprococcus, #Ruminococcus 2, #Butyricicoccus, #Dorea, Fusicatenibacter, #Anaerostipes, Clostridium IV were enriched in the healthy controls. - #Blautia, Clostridium IV, #Coprococcus, #Dorea, Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase. - negative correlation between #Dorea, #Butyricicoccus, #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, #Dorea and ESR . - positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms.
• [1.2] [#Diabetes Type 2] [#Short Chain Fatty Acid] 
  - In four other genera (Fusicatenibacter, #Agathobacter, #Butyricicoccus, #Marvinbryantia), a decrease in the T2D group could also be detected. All genera produce short-chain fatty acids
• [1.3] 
  - Patients with axial #Spondyloarthritis (SpA), #Acute anterior uveitis (AAU), and #Crohn’s disease > low abundances of #Lachnospiraceae taxa relative to controls, most notably Fusicatenibacter, which was most abundant in controls receiving NSAID monotherapy and implied to partially mediate higher #Serum CRP.
• [1.4] [#Parkinson’s Disease] [#Short Chain Fatty Acid] 
  - Decreases of short-chain fatty acid-producing genera, Fusicatenibacter, #Faecalibacterium, and #Blautia, as well as an increase of mucin-degrading genus #Akkermansia, predicted accelerated disease progression.
• [1.5] [#Pulmonary tubercolosis, #Tuberculosis] 
  - The genera #Parabacteroides, #Bacteroides, #Lachnoclostridium, and #Fusobacterium were markedly enhanced in the PTB group, while #Roseburia, #Blautia, unidentified #Ruminococcaceae, #Bifidobacterium, #Romboutsia, and Fusicatenibacter were enhanced in the HC group.
• [1.6] [#Fasting] 
  - RIF was associated with significant drops in the levels of seven genera at the end of Ramadan: #Blautia, #Coprococcus, #Dorea, #Faecalicatena, Fusicatenibacter, #Lachnoclostridium, and #Mediterraneibacter.
• [#Fasting] - significant decrease in Fusicatenibacter levels following RIF.
• - #Obesity was positively associated with Fusicatenibacter and #Romboutsia. - Fusicatenibacter and #Romboutsia were positively correlated with an increase in BMI z-score
• - Fusicatenibacter has a strong correlation with higher levels of #Propionate in fecal samples. - This correlation was linked to unhealthy dietary habits and #Obesity
• [1.7] [#Short Chain Fatty Acid] 
  - adults with #Prediabetes > #Metformin > increased the abundance of GM SCFA-producing bacteria M (Fusicatenibacter and #Blautia) - adults with #Prediabetes > linagliptin/#Metformin > Roseburia, Bifidobacterium, and [Eubacterium] hallii group.
• [1.8] [#Blautia, #Ruminococcus] 
  - Specific human gut microbes, including Ruminococcus_E, #Agathobacter, Fusicatenibacter, #Anaerobutyricum, Blautia_A and #Neisseria, were identified as potential consensus microbial biomarkers for #Obesity in the population.

References Notes