Bacteroides ⇒ Bacteroides dorei {10000221} Record Keys Parent:Bacteroides Definition:Bacteroides dorei Details Initialisation date:2019-08-11 LinksSource Meta Information Rank: Species Domain: Bacteria Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Diabetes Type 1] - A study performed in Finnish children found a higher abundance of Bacteriodetes dorei prior to auto-immunity and T1D development. -The Bacteriodetes phyla produce #Lipopolysaccharide (LPS), a potent activator of the innate immune system, that in turn increases the auto-immune response in T1D in NOD mice [1.2] [#Irritable bowel syndrome] - IBS was associated with differential abundance of bacterial taxa such as Bacteroides dorei; metabolites including increased #Tyramine and decreased gentisate and hydrocinnamate; and transcripts related to fructooligosaccharide and polyol utilization. [1.3] [#Bacteroides vulgatus] [#carrot-derived rhamnogalacturonan I] [#Carrot] - cRG-I supplementation (already at an HED of 0.3 g/d) lowered interpersonal compositional differences due to the selective stimulation of taxa that were consistently present among human adults, including OTUs related to Bacteroides dorei/vulgatus and #Bifidobacterium longum (suspected keystone species), #Bacteroides thetaiotaomicron, #Bifidobacterium adolescentis and #Butyrate-producing taxa such as #Blautia sp., #Anaerobutyricum hallii, and #Faecalibacterium prausnitzii. [1.4] - Some specific gut microbes, such as #Akkermansia muciniphila, #Bacteroides vulgatus, Bacteroides dorei, and #Roseburia intestinalis are associated with the development of #Atherosclerosis. [1.5] [#Covid-19] - Higher neutralizing antibody levels at 6 months post-vaccination were associated with specific gut microbial compositions at baseline, such as Bifidobacterium adollescentis and #Bifidobacterium bifidum for BNT162b2 vaccines and #Phocaeicola dorei for CoronaVac vaccines. [1.6] [#Clostridium symbiosum, #Lachnoclostridium clostridioforme] - The absence of B. dorei impacted the abundance of the other 10 species negatively. - #Lachnoclostridium symbiosum, a #Butyrate producer, appeared to be the most sensitive species to deletions, being stimulated by the presence of #Escherichia coli, #Bifidobacterium adolescentis, B. dorei, and #Lactobacillus plantarum. - Deletions of Bacteroides dorei and #Lachnoclostridium clostridioforme resulted in lower biomass and higher residual #Inulin. [#Lachnoclostridium clostridioforme] - L. clostridioforme was observed to be essential for #Propionate production, and B. dorei for #Lactate production.References Notes[ ]
