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Clostridium ⇒ Clostridiaceae {10000270}

Record Keys


Organism:
Clostridium
Parent:

Details


Initialisation date:
2020-10-03

Meta Information


Rank:
Genus
Domain:
Bacteria
Zone:[  ]
Enzyme:[  ]
Function:[  ]

Notes:


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References Notes


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Shared Reference Notes


  • [1.61
    - Lactobacillus given to letrozole-treated (induces PCOS) rats reduced androgen levels, improved estrous cyclicity, normalized ovarian morphology, as well as increased Lactobacillus and Clostridium species and decreased Prevotella.
  • [1.62
    - Clostridium spp. destroy tumors by secreting exotoxins that damage the membrane structures of cancer cells and enter cells to disrupt essential cellular functions.
    - The introduction of Clostridium spp. recruits CD8+ T cells, granulocytes, and macrophages to the infection area and induces the release of TNF-related apoptosis-inducing ligand (TRAIL) from neutrophils.
  • [1.63
    - WD consumption in conjunction with Clostridium spp. increased the secondary bile acid deoxycholic acid levels in the ileum, which in turn inhibited Paneth cell function.
  • [1.64
    - Clostridium > negative correlation with with fasting glucose and HbA1c levels > decreased insulin resistance.
  • [1.65
    - ALS in mice> altered bacterial community related to autoimmunity (e.g., Clostridium sp. ASF502, Lachnospiraceae bacterium A4), inflammation (e.g., Enterohabdus Muris,), and metabolism (e.g., Desulfovibrio fairfieldensis) at 1- and 2-month-old SOD1G93A mice, suggesting the early microbial contribution to the pathological changes.

Common References