Disease
Microbiota ☳
Metabolome
Factor
Clostridiaceae ⇒ Clostridium {10000270}
Record Keys
Parent:
Definition: Clostridium
Details
Initialisation date: 2020-10-03
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: Cholesterol-interacting
Notes: Shared Reference Notes
[1.1 ] [#Polycystic ovary syndrome ] #Lactobacillus given to letrozole-treated (induces PCOS) rats reduced androgen levels, improved estrous cyclicity, normalized ovarian morphology, as well as increased #Lactobacillus and Clostridium species and decreased #Prevotella .
[1.2 ] Clostridium spp. destroy tumors by secreting exotoxins that damage the membrane structures of #Cancer cells and enter cells to disrupt essential cellular functions.
- The introduction of Clostridium spp. recruits CD8+ T cells, granulocytes, and macrophages to the infection area and induces the release of TNF-related apoptosis-inducing ligand (TRAIL) from neutrophils.
[1.3 ] [#Crohn’s disease ] #Faecalibacterium prausnitzii , #Roseburia inulinivorans and #Alistipes senegalensis .
- While Clostridium nexile and #Ruminococcus gnavus were found to be enriched.
[1.4 ] [#Bile Acids ] [#Western-style diet ] Clostridium spp. increased the secondary bile acid deoxycholic acid levels in the ileum, which in turn inhibited Paneth cell function.
[1.5 ] [#Diabetes Type 2 ] Clostridium > negative correlation with with fasting glucose and HbA1c levels > decreased insulin resistance.
[1.6 ] [#Amyotrophic lateral sclerosis ] Clostridium sp. ASF502, #Lachnospiraceae bacterium A4), inflammation (e.g., #Enterohabdus Muris ,), and metabolism (e.g., #Desulfovibrio fairfieldensis ) at 1- and 2-month-old SOD1G93A mice, suggesting the early microbial contribution to the pathological changes.
[1.7 ] [#Alzheimer’s disease ] [#Bacillus firmus ] Clostridium sp. Culture-27, and #Deoxyuridine , may play important roles in AD pathology.
[1.8 ] Clostridium and #Faecalibacterium genera.
[1.9 ] [#Lipopolysaccharide ] [#Antibiotic Therapy , #Condition of chronic stress ] #Bacteroides and increased abundance of the genus Clostridium . This was accompanied by increased circulating levels of IL-6 and monocyte chemoattractant protein 1 (MCP-1).
- In a follow-up experiment, animals were fed an antibiotic cocktail in the morning and evening by oral gavage, beginning three days before the stressor and continuing to the end of the experiment. Antibiotic treatment prevented the increases in IL-6 and MCP-1.
- mice receiving the stressor had elevated hepatic portal blood levels of LPS (from the gastrointestinal draining vein) and elevated mRNA expression of IL-1β, IL-6, and TNF in the hypothalamus, though no changes in circulating cytokines. Pretreatment with L. farciminis, antibiotics, and ML-7 all prevented these increases.
[#Culinary herbs and spices ] - six of seven aqueous culinary spice extracts of oregano, ginger, rosemary, cinnamon, black pepper and cayenne pepper were able to promote the growth of #Bifidobacterium spp. in vitro, whereas turmeric was not.
- stimulation of #Lactobacillus spp. and inhibition of certain Clostridium spp. by all seven spices.
- increase in most Clostridium spp. after turmeric and curcumin intervention in a human study.
[1.11 ] [#CVD ] [#Short Chain Fatty Acid ] [#Probiotic , #Probiotic (Bifidobacter and Lactobacilus) ] #Bile Acids can decrease #Cholesterol levels by regulating #Cholesterol metabolism.
- Microbial #Bile Salt hydrolases can increase #Cholesterol disposal rates by accelerating its conversion to #Bile Acids .
- Probiotics from the genera Lactobacillus and Bifidobacterium are efficient reducers of #Cholesterol levels in clinical studies.
- Several candidate next-generation probiotics, including #Akkermansia muciniphila , #Bacteroides spp., Clostridium spp., #Christensenella minuta , Eubacterium spp., and #Faecalibacterium prausnitzii , have been shown to decrease #Cholesterol levels in human or animal studies.
[1.12 ] #Faecalibacterium prausnitzii , Bacteroides–Prevotella group, #Atopobium Cluster, #Enterobacter spp. and Clostridium Cluster IV were higher in BD patients than healthy subjects along with a reduced Bifidobacteria to Enterobacteriaceae ratio,
[1.13 ] #Butyrate -producing bacteria such as Clostridium , #Ruminococcus , #Faecalibacterium spp., #Eubacterium spp., and #Roseburia , were found to decrease in relative frequency in CRC patients.
- #Butyrate inhibited the growth of CRC cells and induced their apoptosis in vitro at pharmacologically high concentrations.
[1.14 ] [#Plastics ] #Muribaculaceae decreased and Clostridium increased in disposable paper cups group.
[1.15 ] #Firmicutes , #Bacteroidetes , #Actinobacteria , #Proteobacteria , and #Fusobacteria can participate in #Tryptophan metabolism, being those belonging to the Clostridium , #Burkholderia , #Streptomyces , #Pseudomonas or #Bacillus genera the most important modulators
[1.16 ] [#High-protein diet ] Clostridium , #Desulfovibrio , #Peptostreptococcus , #Acidaminococcus , #Veillonella , #Propionibacterium , Bacillus, #Bacteroides , #Staphylococcus , and other species of the #Proteobacteria family, and the loss of carbohydrate fermenting bacteria such as #Bacteroides , #Lactobacillus , #Bifidobacterium , #Prevotella , #Ruminococcus , #Roseburia , and #Faecalibacterium .
[1.17 ] [#Infants ] #Lactobacillus , Clostridium , #Staphylococcus , #Streptococcus , #Bacteroides , and #Bifidobacterium
[#Human breast milk ] - Phosphatidylethanolamines (PEs) are integral to the outer Milk fat globules bilayer membrane, and while they are important for human cell proliferation during early life, some bacteria of the Clostridium and #Enterococcus genera use ethanolamine as a source of carbon and nitrogen.
[1.18 ] Clostridium ssp. are required for the biotransformation of catecholamines into their bioactive form owing to their β-glucuronidase enzymes.
[1.19 ] [#Anorexia nervosa ] [#Clostridium bolteae , #Clostridium innocuum ] #Erysipelatoclostridium ramosum , #Blautia species CAG, and Enterocloster bolteae innocuum (Clostridium ) were increased.
[#Anorexia nervosa ] - IN AN > Clostridium counts correlated positively with eating disorder scores.
[#Inflamatory bowel disease ] [#Clostridioides difficile , #Fusobacterium nucleatum ] - F. nucleatum coexists with Clostridium through adhesin RadD, encouraging the intestinal mucus layer’s bacterial biofilm formation in IBD patients. This symbiotic relationship accelerates the extracellular polysaccharides-producing process and chemotaxis level of C. difficile
[1.21 ] [#Natural Small intestine Microbiome ] Clostridium , #Lactobacillus , and #Enterococcus species, are able to penetrate, or attach to, the mucus layer at the epithelium and use the mucus as an energy source
[1.22 ] #Olive oil ingestion in rodents also can promote the growth of certain types of beneficial #Bacteria including species of #Lactobacillus , #Bifidobacterium , #Bacteroides , and Clostridium , and members of the Erysipelotrichaeae.
[1.23 ] [#Athletes ] #Faecalibacterium , #Sutterella , Clostridium , #Haemophilus , and #Eisenbergiella were the most abundant in bodybuilders, while #Bifidobacterium and #Parasutterella were the least abundant.
[1.24 ] [#Crohn’s disease ] [#Dorea longicatena , #Ruminococcus lactaris ] #Proteobacteria and harbored high levels of unusual, bacteria such as #Streptococcus mitis , #Undibacterium oligocarboniphilum, #Sphingomonas melonis and #Gemella haemolysans
- 6 months after surgery samples had elevated proportions of anaerobic bacteria belonging to #Lachnospiraceae (Clostridium nexile, #Blautia wexlereae, #Dorea longicatena).
- Remission was characterized by increased levels of bacteria belonging to #Bacteroides , #Dorea , #Ruminococcus and #Dialister genera, whereas recurrence was associated with increased levels of #Gemmiger formicilis , #Enterococcus durans and #Ruminococcus lactaris.
[1.25 ] #Firmicutes phylum comprises Gram-positive bacteria with low G + C DNA content and is composed of more than 200 different genera, such as #Lactobacillus , #Bacillus , Clostridium , #Enterococcus , and Ruminicoccus.
[#Diabetes Type 1 ] - Studies have reported an increased quantity of #Villanella , Clostridium , and #Bacteroides and a decreased quantity of #Lactobacillus , #Eubacterium rectale , #Blautia coccoides , and #Bifidobacterium in #Children with type 1 diabetes.
- #Diabetes Type 1 > negative correlation has been reported between plasma #Glucose level and #Bifidobacterium , #Lactobacillus spp., and #Firmicutes and #Bacteroidetes spp., while there has been positive correlation between Clostridium and plasma #Glucose level.
[#Irritable bowel syndrome ] - IBS was typified by enhanced quantities of #Firmicutes and specifically in #Ruminococcus , Clostridium , and #Dorea , along with a distinct decrease of beneficial microbes, such as #Bifidobacterium and #Faecalibacterium spp
[1.26 ] [#Inflamatory bowel disease ] Clostridium XlVa cluster and #Ruminococcaceae are also reduced in those with inflammatory bowel disease (IBD) compared to those without disease, which agrees with their protective role in the gut inflammation and an anti-inflammatory effect of #Aspirin on the gut microbiome.
[1.27 ] [#Clostridium cluster IV ] #Parabacteroides , #Bilophila , and Clostridium IV, but negatively correlated with the abundance of #Prevotella .
[1.28 ] #Leptin serum level was positively correlated with the abundance of #Bifidobacterium and ##Lactobacillus whereas #Leptin serum level was negatively correlated with Clostridium , #Bacteroides and, #Prevotella
[1.29 ] [#Clostridium orbiscindens ] Clostridium CAG:58 and Clostridium orbiscindens, instead correlate positively with #Obesity
- #Behcet’s Disease > Stool samples were enriched with #Parabacteroides , sulphate-reducing bacteria #Bilophila and #Desulfovibrionaceae species. In addition, it was also noted that #Butyrate -producing bacteria Clostridium and methanogens were reduced.
- Transplantation of BD faeces in mice illustrated remarkable results in which gut integrity was breached due to decreased expression of tight junctions, with the subsequent effects of experimental uveitis.
- The Clostridium genus represents 95% of #Firmicutes .
[1.31 ] [#High fibre diet ] Clostridium genus are also associated to higher dietary fibre intake.
[1.32 ] #Ruminococcus and Clostridium , and some gram-negative bacteria can metabolize #Bile Acids .
[1.33 ] [#Spondyloarthritis ] #Bacilli , order #Lactobacillales , families #Lactobacillaceae and #Clostridiaceae , and genera #Lactobacillus and Clostridium in non-colonized SpA patients.
[1.34 ] [#Clostridiales XIV , #Clostridium cluster IV ] #Walnut consumption at 42 g/day, increased #Butyrate -producing Clostridium clusters XIV and IV including, #Faecalibacterium , #Roseburia , while lowering the relative abundance of #Ruminococcus , #Dorea , Oscilllo, #Bifidobacteria .
[1.35 ] [#Hepatocellular cancer ] [#Bacteroides-Prevotella group , #Clostridium clusters XIVa ] #Bacteroides , #Lachnospiracea #Incertae sedis , and Clostridium XIVa were higher in the gut of non-small-cell HCC group (higher tumor load) and could separate the non-small-cell liver cancer group from small-cell HCC group (lower tumor load)
[1.36 ] [#Clostridioides difficile ] [#Berberine ] #Bacteria such as Clostridium difficile, #Actinobacillus , and #Bacillus subtilis
[1.37 ] [#Bifidobacterium infantis , #Bifidobacterium longum , #Clostridioides difficile , #Kingella denitrificans , #Propionibacterium freudenreichii ] #Vitamin B12 producer are > #Pseudomonas denitrificans , #Bacillus megaterium , and Propionibacterium freudenreichi, #Bacteroides fragilis , #Prevotella copri , Clostridium difficile, #Faecalibacterium prausnitzii , #Ruminococcus lactaris , #Bifidobacterium animalis , B.infantis, B.longum, and #Fusobacterium varium
[#Clostridioides difficile , #Lactobacillus bulgaricus , #Lactobacillus delbrueckii , #Limosilactobacillus (Lactobacillus) reuteri ] - There are several bacteria that can produce #Folate in the gut, which include #Bacteroides fragilis , #Prevotella copri , Clostridium difficile, #Lactobacillus plantarum , L. reuteri, L. delbrueckii ssp. bulgaricus, #Streptococcus thermophilus , #Bifidobacterium spp. (some species), #Fusobacterium varium , and #Salmonella enterica
[1.38 ] #Bifidobacterium , Clostridium , and #Lactobacillus , can produce enzymes such as β-glucuronidases that modify excreted estrogens, causing them to be retained in the body via reabsorption into circulation. This leads to increased #Estrogen levels which can cause several hormone-linked diseases.
[1.39 ] [#Oral squamous cell carcinoma ] #Fusobacterium , #Veillonella , #Actinomyces , Clostridium , #Haemophilus , and #Enterobacteriaceae
[#Clostridium cluster IV , #Clostridium clusters XIVa ] [#Butyrate ] - The predominant butyrogenic bacterial species, including #Faecalibacterium prausnitzii , Clostridium spp., #Eubacterium spp., and #Roseburia spp., are from two clusters (Clostridium clusters IV and XIVa) in the #Firmicutes phylum and the #Clostridiales order
[1.41 ] #Melanoma > Taxa that were more abundant in tumors of responders included Clostridium , whereas #Gardnerella vaginalis was more abundant in tumors of nonresponders.
[1.42 ] #Bacteroides and Clostridium have been reported to be capable of converting #Tryptophan into #Indole and #Indole derivatives
[#Clostridium clusters XIVa ] - Components with the[N(CH3)3] structure, such as #Choline , #Phosphatidylcholine , and L-#Carnitine , can be used by Clostridium (primarily Clostridium XIVa and #Eubacterium ) and Proteobacterium produced trimethylamine (#TMA ) lyases to form #TMA .
- #TMA is a foul-smelling gas that smells like rotten fish
- #Lactobacillus , #Enterococcus , Clostridium , and #Proteus are gastrointestinal tract (GIT) bacteria that can use the #Triglyceride backbone as an electron sink, reducing glycerol to 1,3-propanediol
[#Diabetes Type 2 ] - #Proteobacteria and Clostridium abundance increased in T2DM patients
[1.43 ] [#Clostridium asparagiforme , #Clostridium citroniae , #Clostridium hathewayi , #Clostridium sporogenes ] [#TMA , #TMAO ] Clostridium sp (C asparagiforme, C citroniae, C hathewayi, and C sporogenes), #Desulfovibrio , and #Enterobacteriaceae (#Escherichia coli and #Acinetobacter sp), can respond to a diet rich in #Choline , an essential nutrient for omnivores, and convert it to trimethylamine, which is then metabolised in the liver to trimethylamine N-oxide, a microbiome derived proatherogenic metabolite.
[1.44 ] [#Autism ] [#4EPS ] Clostridium spp. are highly abundant in autistic individuals and yield #4EP precursors.
[1.45 ] [#Clostridium cluster IV ] #Alistipes , Clostridium IV and #Tannerella , might contribute to the transformation of steroidal hormones by their metabolic products.
- Clostridium spp. have been reported to produce enzymes that modify steroidal hormones
Intervention in Disease
Author: MetaBiomIdentifier: 10000270URL: https://www.metabiom.org/microbiota/165/clostridiumKeywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Polycystic Ovary Syndrome and the Gut Microbiome 80001774 ]
[1.2 ] Tweak to Treat: Reprograming Bacteria for Cancer Treatment 80001782 ]
[1.3 ] Ectopic gut colonization: a metagenomic study of the oral and gut microbiome in Crohn’s disease 80001846 ]
[1.4 ] Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation 80001850 ]
[1.5 ] Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives 80002107 ]
[1.6 ] Aberrant enteric neuromuscular system and dysbiosis in amyotrophic lateral sclerosis 80002373 ]
[1.7 ] Gut microbiota may be involved in Alzheimer’s disease pathology by dysregulating pyrimidine metabolism in APP/PS1 mice 80002507 ]
[1.8 ] The double-edged sword of probiotic supplementation on gut microbiota structure in <i>Helicobacter pylori</i> management 80002569 ]
[1.9 ] Finding intestinal fortitude: Integrating the microbiome into a holistic view of depression mechanisms, treatment, and resilience 80002658 ]
[1.10 ] Gut microbial modulation by culinary herbs and spices 80002681 ]
[1.11 ] Gut microbiome-mediated mechanisms for reducing cholesterol levels: implications for ameliorating cardiovascular disease 80002694 ]
[1.12 ] [2023] [Review] [Molecular Psychiatry] [Journal] [80002728 ]
[1.13 ] Microbial Metabolite Dysbiosis and Colorectal Cancer 80002741 ]
[1.14 ] Effects of common plastic products heat exposure on cognition: Mediated by gut microbiota 80002824 ]
[1.15 ] Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities 80002837 ]
[1.16 ] Gut-Muscle Axis Exists and May Affect Skeletal Muscle Adaptation to Training 80002842 ]
[1.17 ] The role of human milk fats in shaping neonatal development and the early life gut microbiota 80002843 ]
[1.18 ] The Gut Microbiota Links Dietary Polyphenols With Management of Psychiatric Mood Disorders 80002856 ]
[1.19 ] The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice 80002863 ]
[1.20 ] Regulatory effects of oral microbe on intestinal microbiota and the illness 80002875 ]
[1.21 ] The emerging role of the small intestinal microbiota in human health and disease 80002887 ]
[1.22 ] Extra-virgin olive oil and the gut-brain axis: influence on gut microbiota, mucosal immunity, and cardiometabolic and cognitive health 80002976 ]
[1.23 ] Intertwined Relationship of Mitochondrial Metabolism, Gut Microbiome and Exercise Potential 80003004 ]
[1.24 ] Alterations of gut microbiome following gastrointestinal surgical procedures and their potential complications 80003038 ]
[1.25 ] Gut Microbiome–Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders 80003039 ]
[1.26 ] Randomised clinical study: oral aspirin 325 mg daily vs placebo alters gut microbial composition and bacterial taxa associated with colorectal cancer risk 80003057 ]
[1.27 ] Gut microbiota and its relation to inflammation in patients with bipolar depression: a cross-sectional study 80003100 ]
[1.28 ] Targeting gut microbiota in osteoporosis: impact of the microbial based functional food ingredients 80003111 ]
[1.29 ] Gut microbiota in a mouse model of obesity and peripheral neuropathy associated with plasma and nerve lipidomics and nerve transcriptomics 80003115 ]
[1.30 ] The Link Between Gastrointestinal Microbiome and Ocular Disorders 80003145 ]
[1.31 ] Gut microbiome and nutrition-related predictors of response to immunotherapy in cancer: making sense of the puzzle 80003179 ]
[1.32 ] Perturbations in gut microbiota composition in patients with polycystic ovary syndrome: a systematic review and meta-analysis 80003217 ]
[1.33 ] Differential gut microbiome in spondyloarthritis patients associated to Blastocystis colonization 80003286 ]
[1.34 ] Gut microbiome changes induced by a diet rich in fruits and vegetables 80003292 ]
[1.35 ] The Role of Gut Microbiome in Hepatocellular Carcinoma: A Systematic Review 80003301 ]
[1.36 ] Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine 80003303 ]
[1.37 ] B Vitamins and Their Roles in Gut Health 80003304 ]
[1.38 ] Never fear, the gut bacteria are here: Estrogen and gut microbiome-brain axis interactions in fear extinction 80003326 ]
[1.39 ] Role of Oral Microbiota in Cancer Development 80003331 ]
[1.40 ] Gut Microbial Metabolite Butyrate and Its Therapeutic Role in Inflammatory Bowel Disease: A Literature Review 80003363 ]
[1.41 ] The human tumor microbiome is composed of tumor type–specific intracellular bacteria 80003370 ]
[1.42 ] A review of the interaction between diet composition and gut microbiota and its impact on associated disease 80003491 ]
[1.43 ] Evidence for clinical interventions targeting the gut microbiome in cardiometabolic disease 80003528 ]
[1.44 ] 4-Ethylphenol—fluxes, metabolism and excretion of a gut microbiome derived neuromodulator implicated in autism 80003537 ]
[1.45 ] Probiotics Bifidobacterium lactis M8 and Lactobacillus rhamnosus M9 prevent high blood pressure via modulating the gut microbiota composition and host metabolic products 80003568 ]
[1.46 ] Characterization of gut microbiota composition and functions in patients with chronic alcohol overconsumption 80001029 ]
[1.47 ] Temporal and long-term gut microbiota variation in allergic disease: a prospective study from infancy to school age 80001034 ]
[1.48 ] Gut microbiota dysbiosis is associated with altered bile acid metabolism in infantile cholestasis 80001288 ]
[1.49 ] Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis 80000689 ]
[1.50 ] Microbiome in Chronic Kidney Disease (CKD): An Omics Perspective 80002388 ]
[1.51 ] Intestinal microflora in patients with liver cirrhosis 80000238 ]
[1.52 ] Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation 80000587 ]
[1.53 ] Decreased fecal bacterial diversity and altered microbiome in children colonized with Clostridium difficile 80000958 ]
[1.54 ] Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease 80000679 ]
[1.55 ] Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment 80000991 ]
[1.56 ] Molecular-phylogenetic characterization of the microbiota in ulcerated and non-ulcerated regions in the patients with Crohn’s Disease 80000576 ]
[1.57 ] Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study 80000311 ]
[1.58 ] Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota 80000711 ]
[1.59 ] Featured gut microbiomes associated with the progression of chronic hepatitis B disease 80001369 ]
[1.60 ] Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma 80000859 ]
[1.61 ] Alterations of the gut microbiome in hypertension 80000630 ]
[1.62 ] Characterization of the gut microbiota of Kawasaki disease patients by metagenomic analysis 80000556 ]
[1.63 ] Conjuctival dysbiosis in mucosa-associated lyphoid tissue lymphoma 80001109 ]
[1.64 ] Gut microbiome of treatment-naïve MS patients of different ethnicities early in disease course 80001262 ]
[1.65 ] Correlation between body mass index and faecal microbiota from children. 80000316 ]
[1.66 ] The microflora associated with human oral carcinomas 80000771 ]
[1.67 ] Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. 80000242 ]
[1.68 ] Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation 80001256 ]
[1.69 ] Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy 80000594 ]
[1.70 ] Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis 80000752 ]
[1.71 ] An increased abundance of clostridiaceae characterizes arthritis in inflammatory bowel disease and rheumatoid arthritis: a cross-sectional study 80000856 ]
[1.72 ] Analysis of gut microbiota diversity and auxiliary diagnosis as a biomarker in patients with schizophrenia: a cross-sectional study 80000800 ]
[1.73 ] Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjögren’s Syndrome 80001479 ]
[1.74 ] Intestinal dysbiosis in inflammatory bowel disease associated with primary immunodeficiency 80000914 ]
[1.75 ] Gut microbiota alterations in Alzheimer’s Disease 80000621 ]
[1.76 ] Potential role of gut microbiota in ALS pathogenesis and possible novel therapeutic strategies 80000818 ]
[1.77 ] Role of the gut microbiota in the development of various neurological diseases 80002479 ]
[1.78 ] Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis. 80000612 ]
[1.79 ] Microbiota in anorexia nervosa: the triangle between bacterial species, metabolites and psychological tests 80000755 ]
[1.80 ] Mucosal Microbiome in Patients with Recurrent Aphthous Stomatitis 80000521 ]
[1.81 ] Distinct pattern of commensal gut microbiota in toddlers with eczema 80000546 ]
[1.82 ] A metagenomic study of the gut microbiome in Behcet’s disease 80000793 ]
[1.83 ] Alteration of the gut microbiota in Chinese population with chronic kidney disease 80000616 ]
[1.84 ] The lung microbiome in moderate and severe chronic obstructive pulmonary disease. 80000385 ]
[1.85 ] Severe COVID-19 Is Associated With an Altered Upper Respiratory Tract Microbiome 80002311 ]
[1.86 ] Metagenomic analysis of crohn’s disease patients identifies changes in the virome and microbiome related to disease status and therapy, and detects potential interactions and biomarkers 80000446 ]
[1.87 ] Colinic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype 80001200 ]
[1.88 ] Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents 80001376 ]
[1.89 ] Gut microbiome and serum metabolome analyses identify molecular biomarkers and altered glutamate metabolism in fibromyalgia 80001184 ]
[1.90 ] Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure. 80000396 ]
[1.91 ] Evolution of the gut microbiome following acute HIV-1 infection 80001103 ]
[1.92 ] Gut microbiota dysbiosis contributes to the development of hypertension 80000033 ]
[1.93 ] Alterations in the gut bacterial microbiome in fungal keratitis patients 80000884 ]
[1.94 ] Specific gut microbiome signature predicts the early-stage lung cancer 80001413 ]
[1.95 ] Reduced anti-inflammatory gut microbiota are associated with depression and anhedonia 80001308 ]
[1.96 ] Fecal and blood microbiota profiles and presences of nonalcoholic fatty liver disease in obese versus lean subjects 80001021 ]
[1.97 ] An altered composition of the microbiome in microscopic colitis is driven towards the composition in healthy controls by treatment with budesonide 80001213 ]
[1.98 ] Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to Clostridia XIVa and IV clusters. 80000233 ]
[1.99 ] Altered gut microbiota in myasthenia gravis 80000850 ]
[1.100 ] Alteration of the fecal microbiota in North-Eastern Han Chinese population with sporadic Parkinson’s disease 80001306 ]
[1.101 ] Aberrant intestinal microbiota in individuals with prediabetes 80000677 ]
[1.102 ] Differences in gut microbiome composition between persons with chronic schizophrenia and healthy comparison subjects 80000808 ]
[1.103 ] Shared gut, but distinct oral microbiota composition in primary Sjögren’s syndrome and systemic lupus erythematosus_DUBLICATE 80000923 ]
[1.104 ] Comparison of the ocular microbiome between chronic Stevens-Johnson syndrome patients and healthy subjects 80001339 ]
[1.105 ] Association of systemic sclerosis with a unique colonic microbial consortium 80000333 ]
[1.106 ] Altered gut microbiome composition in patients with Vogt-Koyanagi-Harada disease 80001255 ]
[1.107 ] Postnatal exposure to ambient air pollutants is associated with the composition of the infant gut microbiota at 6-months of age 80002582 ]
[1.108 ] Rethinking healthy eating in light of the gut microbiome 80002441 ]
[1.109 ] Human milk nutrient fortifiers alter the developing gastrointestinal microbiota of very-low-birth-weight infants 80002552 ]
[1.110 ] Effects of Heat Stress on Gut Microbiome in Rats 80002087 ]
[1.111 ] A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration 80002487 ]
[1.112 ] Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies 80000217 ]
[1.113 ] Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis 80002575 ]
