Bacteroides ⇒ Bacteroides uniformis {10000181}

Shared Reference Notes

• [1.1] [#Anorexia nervosa, #Bulimia nervosa] 
  - Individuals with AN lacking the genomic region of B. uniformis had greater scores for self-denial and bulimia. - The genetic deletion in B. uniformis could result in the deficiency of thiamine, a vitamin associated with intestinal and mental health. - The #Serotonin synthesis module causally affected BMI through #Glycoursodeoxycholic acid, which is upregulated by #Serotonin.
• [1.2] [#Amedibacterium Intestinale] 
  - #Agavins (AG), either alone or combined with cranberry #Polyphenols (CP+AG), mainly stimulated the glycan-degrading bacteria Muribaculum intestinale, #Faecalibaculum rodentium, Bacteroides uniformis, and #Bacteroides acidifaciens. - This increase of glycan-degrading bacteria was consistent with a significantly increased level of #Butyrate in obese mice receiving AG,
• [1.3] [#Acute lymphoblastic leukemia] [#Bacteroides ovatus, #Pseudomonas aurantiaca, #Roseburia intestinalis, #Roseburia inulinivorans] 
  - #Children with ALL exhibit reduced relative abundance of both #Butyrate-producing species (#Roseburia faecis, R. intestinalis, R. inulinivorans, #Anaerostipes hardus, #Faecalibacterium prausnitzii, #Eubacterium ramulus) and #Acetate-producing species (#Prevotella maculosa, P. aurantiaca, Bacteroides uniformis, B. ovatus)
• [#Acute lymphoblastic leukemia] [#Bacteroides ovatus, #Bacteroides vulgatus] [#Cesarean section] - #Children with ALL at the time of diagnosis were reported to have reduced relative abundance of B. vulgatus, B. ovatus and B. uniformis; that is, immunomodulatory bacterial species whose transmission from mother to child is disrupted by C-section
• [#Bacteroides ovatus] [#Infants] - #Bacteroides species (for example, B. ovatus and B. uniformis), whose successful and timely colonization is determined by the mode of delivery, can have a profound impact on stool IgA levels during infancy.
• [1.4] [#Short Chain Fatty Acid] [#Exercise training] 
  - #Acetate and #Propionate are associated with increased B. uniformis abundance in the gut. - These SCFAs may facilitate muscle #Glucose supply from the liver during exercise.
• [#Short Chain Fatty Acid] [#Exercise training] - B. uniformis administration in mice increased swimming time to exhaustion, cecal short-chain fatty acid concentrations, and the gene expression of enzymes associated with gluconeogenesis in the liver while decreasing hepatic glycogen content.
• [#α-cyclodextrin] [#Exercise training] - the supplementation with α-cyclodextrin (αCD) in human males increased gut B. uniformis abundance and improved endurance exercise performance
• [1.5] [#Bacteroides vulgatus] 
  - #Bacteroidin-2 (produced by #Bacteroides cellulosilyticus) targeted several different classes including nearly all #Bacteroidia in our panel (except for B. uniformis and B. vulgatus), as well as #Akkermansia muciniphila, and #Eubacterium rectale of the #Verrucomicrobiae and #Clostridia classes, respectively.
• [1.6] [#Bacteroides ovatus, #Bacteroides vulgatus] [#Short Chain Fatty Acid] 
  - the size of the left nucleus accumbens were dominated by Bacteroides species, especially B. vulgatus, B. uniformis, and B. ovatus. B. ovatus has been shown to produce a number of neuroactive compounds including SCFAs and #Neurotransmitters such as γ-aminobutyric acid (#GABA)
• [1.7] [#Escherichia coli, #Faecalibacterium prausnitzii, #Parabacteroides distasonis] [#Fasting] 
  - During IER > the abundance of #Obesity-related probiotics including F. prausnitzii, P. distasonis, and B. uniformis significantly increased compared with that at baseline, whereas the abundance of pathogenic E. coli significantly decreased. - the reduction in E.coli abundance sustained to the endpoint of phase III, whereas the abundance of F. prausnitzii, P. distasonis, and B. uniformis peaked at midpoint of phase II and declined to near baseline levels at endpoint of phase III.
• [#Faecalibacterium prausnitzii, #Parabacteroides distasonis] - F. prausnitzii, P. distasonis, and B. uniformis can reduce #Obesity and alleviate #Obesity-related metabolic and immune disorders
• [1.8] [#3-succinylated cholic acid] 
  - Bacteroides uniformis strains as effective producers of 3-sucCA both in vitro and in vivo. By activity-based protein purification and identification, we identified an enzyme annotated as β-lactamase in B. uniformis responsible for 3-sucCA biosynthesis.
• [1.9] 
  - soluble fiber #Inulin or #Guar gum, but not insoluble fiber cellulose, promoted colorectal tumorigenesis in AOM-treated and Apcmin/+ mice. - Soluble fiber induced gut dysbiosis with Bacteroides uniformis enrichment and #Bifidobacterium pseudolongum depletion, accompanied by increased fecal #Butyrate and serum #Bile Acids and decreased #Inosine.

References Notes