Vitamin B6 {90000340} Record Keys Parent:[ ] Definition:Vitamin B6 Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:Vitamin Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Parkinson’s Disease] - vitamin B6 is a critical cofactor for a wide range of biochemical reactions, including the synthesis of #Dopamine. - vitamin B6 intake was associated with a reduced risk of developing PD. [1.2] [#Irritable bowel syndrome] [#Vitamin D] - deficiency in levels of both vitamins D and B6 have emerged as causative factors in IBS symptoms pathogenesis. [1.3] - #Bacteroides fragilis and #Prevotella copri (#Bacteroidetes), #Bifidobacterium longum and #Collinsella aerofaciens (#Actinobacteria), and #Helicobacter pylori (#Proteobacteria) can produce vitamin B6 as they have these biosynthetic mechanisms - the abundance of #Bacteroides was decreased when the vitamin B6 intake was high - #Bifidobacterium, #Slackia, #Enterococcus, Thiococcus, #Klebsiella, #Serratia, and #Enterobacter abundances were also decreased with vitamin B6 supplementation in #Lactose-intolerant patients . [#Irritable bowel syndrome] - sever of irritable bowel disease symptoms > low dietary vitamin B6 intake [#Lachnospiraceae] - An abundance of Lachnospiraceae_NK4A136_group and #Prevotella were elevated with vitamin B6 deficiency, - Vitamin B6 has six vitamers, namely, pyridoxine (PN); pyridoxal (PL); pyridoxamine (PM); and their phosphorylated forms, i.e., pyridoxal phosphate (PLP), pyridoxine phosphate (PNP), and pyridoxamine phosphate (PMP). - PLP is the enzymatically most active form of vitamin B6. - Vitamin B6 acts as a cofactor for many biochemical reactions, primarily involved in amino acid biosynthesis and catabolism. Besides this, it is involved in fatty acid and neurotransmitter biosynthesis and also acts as an antioxidant - vitamin B6 deprivation > significant decrease in the number of mucous-secreting cells, a critical factor in maintaining gut healthReferences Notes[ ]
