Vitamin B6 {90000340}

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Vitamin B6
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Shared Reference Notes

  • [1.1] [#Parkinson’s Disease
    - vitamin B6 is a critical cofactor for a wide range of biochemical reactions, including the synthesis of #Dopamine. - vitamin B6 intake was associated with a reduced risk of developing PD.
  • [1.2] [#Irritable bowel syndrome] [#Vitamin D
    - deficiency in levels of both vitamins D and B6 have emerged as causative factors in IBS symptoms pathogenesis.
  • [1.3
    - #Bacteroides fragilis and #Prevotella copri (#Bacteroidetes), #Bifidobacterium longum and #Collinsella aerofaciens (#Actinobacteria), and #Helicobacter pylori (#Proteobacteria) can produce vitamin B6 as they have these biosynthetic mechanisms
  • - the abundance of #Bacteroides was decreased when the vitamin B6 intake was high
  • - #Bifidobacterium, #Slackia, #Enterococcus, Thiococcus, #Klebsiella, #Serratia, and #Enterobacter abundances were also decreased with vitamin B6 supplementation in #Lactose-intolerant patients .
  • [#Irritable bowel syndrome] - sever of irritable bowel disease symptoms > low dietary vitamin B6 intake
  • [#Lachnospiraceae] - An abundance of Lachnospiraceae_NK4A136_group and #Prevotella were elevated with vitamin B6 deficiency,
  • - Vitamin B6 has six vitamers, namely, pyridoxine (PN); pyridoxal (PL); pyridoxamine (PM); and their phosphorylated forms, i.e., pyridoxal phosphate (PLP), pyridoxine phosphate (PNP), and pyridoxamine phosphate (PMP). - PLP is the enzymatically most active form of vitamin B6. - Vitamin B6 acts as a cofactor for many biochemical reactions, primarily involved in amino acid biosynthesis and catabolism. Besides this, it is involved in fatty acid and neurotransmitter biosynthesis and also acts as an antioxidant
  • - vitamin B6 deprivation > significant decrease in the number of mucous-secreting cells, a critical factor in maintaining gut health

References Notes

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Common References

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