Disease ⇒ Primary sclerosing cholangitis {40000179}
| Type: | Disease |
|---|---|
| Parent: | [ ] |
| Definition: | Primary sclerosing cholangitis |
| Initialisation date: | 2020-09-20 |
|---|---|
| Other Terms: | PSC |
| MedDra ID: | 10008609 |
|---|---|
| MedDra Level: | pt |
| ICD: | [ ] |
| Category: | Rheumatology |
| Zone: | [ ] |
| Mechanism: | [ ] |
Notes:
- The salivary microbial signature of PSC was significantly altered as compared to healthy controls, independent of concomitant IBD, and was comprised of 19 significantly altered species, of which, eight species were consistently overrepresented in both fecal and saliva of patients with PSC, including Veillonella, Scardovia and Streptococcus. (1)
Shared Reference Notes
- [1.1]
- The aggregated relative abundance of #Klebsiella species was significantly higher in patients with #Crohn’s disease and primary sclerosing cholangitis when compared with healthy controls. - Several genes increased in the faecal microbiomes of patients with inflammatory bowel diseases > include hemolysin-coregulated protein and enzymes involved in fructose-, galactitol-, mannose-, and long-chain fatty acid-related uptake and metabolic pathways- were enriched in most faecal samples of the patients with inflammatory disease who carried #Klebsiella species.
References Notes
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