IL-2 {90000272} Record Keys Parent:[ ] Definition:IL-2 Queue:[ ] Details Initialisation date:2022-02-25 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [1.2] [#Systemic lupus erythematosus] - SLE patients displayed higher serum levels of IL-2 and #IL-6. - The abundance of #Roseburia and #Faecalibacterium was inversely correlated with #IL-6, the abundance of #Roseburia had a negative correlation with IL-2, and the abundance of #Bacteroides had a positive correlation with IL-2. [1.3] - prevention of cytokine storm in ill patients > by #Polyphenols and #Phytosterols, which, through their effects on macrophages, inhibit the secretion of the pro-inflammatory mediators interleukin-1-beta (IL-1ß), IL-2, #IL-6, γ-interferon (IFN-γ), and tumor necrosis factor α (TNF-α) reducing inflammation caused by hyperactivation of cytokines [1.4] [#TNF-alfa] - anti-inflammatory cytokines (IL-4 and #IL-10) and proinflammatory cytokines (TNF-a, #IL-1b, IL-2, #IL-6, #IL-8, #IL-12, #IL-17, and #IL-18) are significantly changed by #Lactobacillus rhamnosus GG (LGG) [1.5] - #Lactobacillus casei can increase anti-inflammatory cytokines (such as #IL-10, TGF-β) and inhibit pro-inflammatory cytokines (such as IL-1β, IL-2) - #Lactobacillus casei can promote the differentiation of CD4+ T cells into Treg and inhibit their differentiation into Th17 cells, thereby regulating immune functionReferences Notes[ ]
