Methanobacteria ⇒ Methanobacteriales {10000186} Record Keys Parent:Methanobacteria Definition:Methanobacteriales Details Initialisation date:2022-01-03 Meta Information Rank: Order Domain:Archaea Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - The most prevalent archaea in the human gut are Methanobacteriales and #Methanomassiliicoccales. - Methanobacteriales are mainly represented by Methanobrevibacter smithii (prevalence of up to 97.5%) and Methanosphaera stadtmanae (prevalence of up to 23%). - #Methanomassiliicoccales have only recently been discovered and identified in the human gut, with Methanomassiliicoccus luminyensis13, Candidatus Methanomassiliicoccus intestinalis14, Ca. Methanomethylophilus alvus15, and the strains Mx02, Mx03 and Mx06, being most prevalent [1.2] [#Irritable bowel syndrome] - symptom severity is related to characteristic alterations of gut microbiota, including reduced diversity, reduced exhaled methane, relative reduction of Methanobacteriales and #Prevotella enterotype, and abundance of #Bacteroides enterotype. - #Bacteroides were found to be increased in patients with IBS-D and were associated with mucosal low-grade inflammation. [1.3] [#Covid-19] [#mRNA vaccine] - high spike IgG levels, with less abundance of bacterial groups belonging to #Clostridiales and Methanobacteriales, such as #Ruminococcaceae #DTU089 and #Methanobrevibacter, respectively. References Notes[ ]