Disease ⇒ HIV infection {40000212}

Record Keys
Type:	Disease
Parent:	[ ]
Definition:	HIV infection

Details
Initialisation date:	[ ]
Other Terms:	[ ]

Meta Information
MedDra ID:	10000807
MedDra Level:	pt
ICD:	[ ]
Category:	[ ]
Zone:	[ ]
Mechanism:	[ ]

Notes:

[ ]

Shared Reference Notes

[1.1]
- HIV-related shifts in the mucosal microbiome aren’t always mirrored in fecal samples from the same individual > a pronounced difference between the mucosal-associated and fecal-associated microbiomes, with only the former closely tied to accelerated biological #Aging.
- Specific bacterial genera, including #Catenibacterium, #Prevotellaceae, and #Enterobacteriaceae, enriched in PLWH > were strongly associated with accelerated biological #Aging. - These bacterial taxa can catabolize #Tryptophan and were correlated with elevated levels of the metabolic byproducts of #Tryptophan catabolism. Increased #Tryptophan catabolism leads to an accumulation of toxic metabolic byproducts such as #kynurenine and #Quinolinic acid. - These byproducts have been linked with adverse outcomes in chronic HIV infection
- #Quinolinic acid, a known neurotoxin and activator of the #N-methyl-D-aspartate (NMDA) receptor, has been connected to neurological complications in HIV infection.

References Notes

[ ]

↥ Microbiota

‐ Achromobacter Cervicovaginal lavage Human [1.2]
‐ Acidaminococcus fermentans Stool Human [1.3]
‐ Acinetobacter Tissue biopsie Human [1.4]
‐ Allisonella histaminiformans Stool Human [1.3]
‐ Allisonella Stool Human [1.5]
‐ Anaerococcus Rectal lavage sample Human [1.6]
‐ Anaerococcus Rectal swab Human [1.7]
‐ Anaerotruncus Stool Human [1.8]
‐ Anaerovibrio Stool Human [1.5]
‐ Asaccharobacter Cervicovaginal lavage Human [1.2]
‐ Barnesiella Stool Human [1.9]
‐ Brachyspira Stool Human [1.10]
‐ Brucellaceae Tissue biopsie Human [1.4]
‐ Bulleidia Stool Human [1.3]
‐ Campylobacter Stool Human [1.10]
‐ Candida albicans Stool Human [1.11]
‐ Candida tropicalis Stool Human [1.11]
‐ Candida Oral wash Human [1.12]
‐ Capnocytophaga ochracea Palatine tonsil swab Human [1.13]
‐ Capnocytophaga Oral wash Human [1.12]
‐ Catenibacterium mitsuokai Stool Human [1.3]
‐ Catenibacterium Stool Human [1.10]
‐ Citrobacter Cervicovaginal lavage Human [1.2]
‐ Corynebacterium Rectal swab Human [1.14]
‐ Desulfovibrio piger Stool Human [1.3]
‐ Dialister propionicifaciens Stool Human [1.3]
‐ Dietzia Rectal swab Human [1.14]
‐ Eisenbergiella Stool Human [1.15]
‐ Enterobacteriaceae Stool Human [1.10]
‐ Enterobacter Stool Human [1.5]
‐ Erysipelotrichaceae Stool Human [1.9]
‐ Erysipelotrichaceae Tissue biopsie Human [1.16]
‐ Escherichia Stool Human [1.10]
‐ Escherichia Tissue biopsie Human [1.16]
‐ Eubacterium biforme Stool Human [1.3]
‐ Finegoldia Rectal swab Human [1.14]
‐ Firmicutes Stool Human [1.17]
‐ Fusobacteriaceae Stool Human [1.10]
‐ Fusobacterium Rectal lavage sample Human [1.6]
‐ Fusobacterium Rectal swab Human [1.18]
‐ Fusobacterium Stool Human [1.5]
‐ Gammaproteobacteria Stool Human [1.9]
‐ Gardnerella Rectal swab Human [1.18]
‐ Haemophilus parainfluenzae Saliva Human [1.19]
‐ Haemophilus Stool Human [1.20]
‐ Helicobacter Rectal swab Human [1.18]
‐ Howardella Stool Human [1.5]
‐ Klebsiella Tissue biopsie Human [1.16]
‐ Lactobacillus Rectal swab Human [1.18]
‐ Malassezia restricta Stool Human [1.11]
‐ Megasphaera elsdenii Stool Human [1.3]
‐ Mitsuokella jalaludinii Stool Human [1.3]
‐ Mogibacterium Stool Human [1.10]
‐ Murdochiella Rectal swab Human [1.14]
‐ Mycoplasma Cervicovaginal lavage Human [1.2]
‐ Nakaseomyces Stool Human [1.11]
‐ Negativicoccus Rectal swab Human [1.14]
‐ Neisseria cinerea Palatine tonsil swab Human [1.13]
‐ Oscillibacter Stool Human [1.15]
‐ Oscillospira Stool Human [1.8]
‐ Paraprevotella Stool Human [1.5]
‐ Pelomonas Oral wash Human [1.21]
‐ Peptoniphilus Rectal swab Human [1.14]
‐ Peptostreptococcus Rectal lavage sample Human [1.6]
‐ Porphyromonas Rectal lavage sample Human [1.6]
‐ Porphyromonas Rectal swab Human [1.14]
‐ Prevotella copri Stool Human [1.3]
‐ Prevotella melaninogenica Saliva Human [1.22]
‐ Prevotella stercorea Stool Human [1.3]
‐ Prevotella Rectal swab Human [1.14]
‐ Prevotella Stool Human [1.10]
‐ Prevotella Tissue biopsie Human [1.4]
‐ Propionibacteriaceae Cervicovaginal lavage Human [1.23]
‐ Propionibacterium Cervicovaginal lavage Human [1.2]
‐ Proteobacteria Stool Human [1.24]
‐ Pseudoflavonifractor Rectal swab Human [1.14]
‐ Pseudomonadales Plasma Human [1.25]
‐ Ralstonia Stool Human [1.10]
‐ Rothia mucilaginosa Saliva Human [1.22]
‐ Ruminococcus callidus Stool Human [1.3]
‐ Ruminococcus Stool Human [1.8]
‐ Salmonella Tissue biopsie Human [1.16]
‐ Selenomonas noxia Palatine tonsil swab Human [1.13]
‐ Serratia Tissue biopsie Human [1.16]
‐ Shigella Tissue biopsie Human [1.16]
‐ Sneathia Rectal swab Human [1.18]
‐ Stenotrophomonas Oral wash Human [1.21]
‐ Streptococcus Palatine tonsil swab Human [1.13]
‐ Streptococcus Rectal swab Human [1.14]
‐ Tropheryma whipplei Bronchoalveolar lavage Human [1.26]
‐ Veillonella Stool Human [1.20]
‐ Xanthomonadaceae Tissue biopsie Human [1.4]

↧ Microbiota

‐ Aggregatibacter Oral wash Human [1.12]
‐ Akkermansia Stool Human [1.10]
‐ Alistipes Rectal lavage sample Human [1.6]
‐ Alistipes Stool Human [1.3]
‐ Alistipes Tissue biopsie Human [1.4]
‐ Alternaria Stool Human [1.11]
‐ Anaerovibrio Stool Human [1.20]
‐ Arcanobacterium Rectal swab Human [1.14]
‐ Ascomycota Stool Human [1.11]
‐ Bacteroides Rectal swab Human [1.14]
‐ Bacteroides Stool Human [1.10]
‐ Bacteroides Tissue biopsie Human [1.4]
‐ Bacteroidetes Stool Human [1.17]
‐ Barnesiellaceae Stool Human [1.10]
‐ Barnesiella Rectal swab Human [1.14]
‐ Barnesiella Stool Human [1.5]
‐ Barnesiella Tissue biopsie Human [1.4]
‐ Bifidobacterium Stool Human [1.20]
‐ Bilophila Stool Human [1.24]
‐ Blastocystis Stool Human [1.27]
‐ Blautia Stool Human [1.10]
‐ Blautia Tissue biopsie Human [1.4]
‐ Brachyspira Rectal swab Human [1.14]
‐ Butyrivibrio Stool Human [1.15]
‐ Campylobacter Bronchial brush Human [1.28]
‐ Campylobacter Rectal swab Human [1.14]
‐ Campylobacter Tissue biopsie Human [1.16]
‐ Christensenellaceae Tissue biopsie Human [1.4]
‐ Clostridium Stool Human [1.20]
‐ Collinsella Stool Human [1.8]
‐ Coprococcus Rectal lavage sample Human [1.6]
‐ Coprococcus Stool Human [1.10]
‐ Coprococcus Tissue biopsie Human [1.4]
‐ Dialister Stool Human [1.10]
‐ Dorea Stool Human [1.10]
‐ Eggerthella Cervicovaginal lavage Human [1.2]
‐ Eggerthella Rectal swab Human [1.18]
‐ Eggerthella Stool Human [1.5]
‐ Enhydrobacter Oral wash Human [1.21]
‐ Enhydrobacter Rectal swab Human [1.18]
‐ Eubacterium Rectal lavage sample Human [1.6]
‐ Faecalibacterium Rectal swab Human [1.14]
‐ Faecalibacterium Stool Human [1.10]
‐ Flavonifractor Rectal swab Human [1.14]
‐ Fusobacterium Bronchial brush Human [1.28]
‐ Fusobacterium Palatine tonsil swab Human [1.13]
‐ Haemophilus Palatine tonsil swab Human [1.13]
‐ Helicobacter Rectal swab Human [1.14]
‐ Lachnobacterium Cervicovaginal lavage Human [1.2]
‐ Lachnospiraceae Tissue biopsie Human [1.4]
‐ Lachnospira Rectal lavage sample Human [1.6]
‐ Lachnospira Stool Human [1.10]
‐ Lactobacillus crispatus Cervicovaginal lavage Human [1.2]
‐ Lactobacillus iners Cervicovaginal lavage Human [1.29]
‐ Mobiluncus Cervicovaginal lavage Human [1.2]
‐ Mycoplasma Cervicovaginal lavage Human [1.2]
‐ Neisseria Palatine tonsil swab Human [1.13]
‐ Odoribacter Stool Human [1.10]
‐ Oscillospira Stool Human [1.10]
‐ Oxalobacter Rectal swab Human [1.14]
‐ Oxalobacter Stool Human [1.5]
‐ Parabacteroides Rectal swab Human [1.14]
‐ Parabacteroides Stool Human [1.3]
‐ Parasutterella Rectal swab Human [1.14]
‐ Parvimonas Oral wash Human [1.21]
‐ Penicillium brevicompactum Stool Human [1.11]
‐ Peptostreptococcaceae Stool Human [1.10]
‐ Pichia Stool Human [1.11]
‐ Prevotella Bronchial brush Human [1.28]
‐ Prevotella Stool Human [1.17]
‐ Propionibacterium Cervicovaginal lavage Human [1.2]
‐ Pseudomonas Tissue biopsie Human [1.16]
‐ Pyramidobacter Stool Human [1.8]
‐ Rikenellaceae Stool Human [1.10]
‐ Romboutsia Stool Human [1.15]
‐ Roseburia Rectal lavage sample Human [1.6]
‐ Roseburia Stool Human [1.10]
‐ Ruminococcaceae Stool Human [1.15]
‐ Ruminococcaceae Tissue biopsie Human [1.4]
‐ Ruminococcus Rectal lavage sample Human [1.6]
‐ Ruminococcus Stool Human [1.10]
‐ Shigella Rectal swab Human [1.14]
‐ Staphylococcus Tissue biopsie Human [1.16]
‐ Stemphylium Oral wash Human [1.21]
‐ Streptococcus mitis Saliva Human [1.19]
‐ Streptococcus Rectal swab Human [1.18]
‐ Succinivibrio Rectal swab Human [1.14]
‐ Thalassospira Tissue biopsie Human [1.4]
‐ Turicibacter Rectal swab Human [1.14]
‐ Veillonella parvula Palatine tonsil swab Human [1.13]
‐ Veillonella Bronchial brush Human [1.28]
‐ Verrucomicrobia Bronchial brush Human [1.28]
‐ Vivictivallis Rectal swab Human [1.14]

Impact by Microbiota

[ ]

↥ Metabolome

[ ]

↧ Metabolome

[ ]

Impact by Metabolome

[ ]

Related Factor

[ ]

Subclass

‐ HIV-infected pneumonia

References

[ ]

MetaBiom
Identifier: 40000212
URL: https://www.metabiom.org/disease/112/hiv-infection
Keywords: Microbiome, Dysbiosis, Chronic

Common References

[1.1] Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging [2024] [80003661]
[1.2] Comparison of lower genital tract microbiota in HIV-infected and uninfected women from Rwanda and the US [2014] [PLOS ONE] [Journal] [80000650]
[1.3] Alterations in the gut microbiota associated with HIV-1 infection [2013] [Cell Host & Microbe] [Journal] [80000339]
[1.4] An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia. [2014] [Mucosal Immunology] [Journal] [80000343]
[1.5] Among older adults, age-related changes in the stool microbiome differ by HIV-1 serostatus [2019] [EBioMedicine] [Journal] [80000999]
[1.6] HIV infection is associated with compositional and functional shifts in the rectal mucosal microbiota [2013] [Microbiome] [Journal] [80000337]
[1.7] Composition of gut microbiota of children and adolescents with perinatal HIV infection taking antiretroviral therapy in Zimbabwe [2019] [Journal of Infectious Diseases] [Journal] [80001052]
[1.8] Altered gut microbiota and host metabolite profiles in women with human immunodeficiency virus [2020] [Clinical Infectious Diseases] [Journal] [80001298]
[1.9] Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection. [2015] [The Journal of Infectious Diseases] [Journal] [80000342]
[1.10] A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. [2014] [PLOS ONE] [Journal] [80000332]
[1.11] Metabarcoding analysis of eukaryotic microbiota in the gut of HIV-infected patients [2018] [PLOS ONE] [Journal] [80000743]
[1.12] Oraly mycobiome analysis of HIV-infected patients: identification of Pichia as an antagonist of opportunistic Fungi [2014] [PLOS ONE] [Journal] [80001216]
[1.13] The palatine tonsil bacteriome, but not the mycobiome, is altered in HIV infection [2018] [BMC Microbiology] [Journal] [80001098]
[1.14] Effects of HIV viremia on the gastrointestinal microbiome of young MSM [2019] [AIDS] [Journal] [80000959]
[1.15] Impact of human immunodeficiency virus-related gut microbiota alterations on metabolic comorbid conditions [2020] [Clinical Infectious Diseases] [Journal] [80001357]
[1.16] Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism [2013] [Science translational medicine] [Journal] [80000345]
[1.17] Alterations in the Fecal Microbiota of Patients with HIV-1 Infection: An Observational Study in A Chinese Population [2016] [Scientific Reports] [Journal] [80000387]
[1.18] Altered immunity and microbial dysbiosis in aged individuals with long-term controlled HIV infection [2019] [Frontiers in Immunology] [Journal] [80000974]
[1.19] The oral microbiome in human immunodeficiency virus (HIV)-positive individuals [2015] [Journal of Medical Microbiology] [Journal] [80000483]
[1.20] Evolution of the gut microbiome following acute HIV-1 infection [2019] [Microbiome] [Journal] [80001103]
[1.21] Dysbiosis in the oral bacterial and fungal microbiome of HIV-infected subjects is associated with clinical and immunologic variables of HIV infection [2018] [PLOS ONE] [Journal] [80000883]
[1.22] Oral microbiome in HIV-infected women: shifts in the abundance of pathogenic and beneficial bacteria are associated with aging, HIV load, CD4 count, and antiretroviral therapy [2019] [AIDS Research and Human Retroviruses] [Journal] [80000982]
[1.23] Comparison of the diversity of the vaginal microbiota in HIV-infected and uninfected women with and without bacterial vaginosis. [2008] [The Journal of Infectious Diseases] [Journal] [80000370]
[1.24] Fecal bacterial microbiome diversity in chronic HIV-infected patients in China. [2016] [Emerging microbes & infections] [Journal] [80000435]
[1.25] Detection and identification of plasma bacterial and viral elements in HIV/AIDS patients in comparison to healthy adults [2012] [Infectious Diseases] [Journal] [80000340]
[1.26] Widespread colonization of the lung by Tropheryma whipplei in HIV infection [2013] [American Journal of Respiratory and Critical Care Medicine] [Journal] [80000351]
[1.27] Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana [2019] [PLOS ONE] [Journal] [80001212]
[1.28] Decreased microbiome diversity in the HIV small airway epithelium [2018] [Respiratory Research] [Journal] [80000817]
[1.29] Pyrosequencing of the genital microbiotas of HIV-seropositive and -seronegative women reveals Lactobacillus iners as the predominant Lactobacillus species. [2011] [Applied and Environmental Microbiology] [Journal] [80000374]

MetaBiom only uses strictly necessary session cookies to give you the best possible experience on the website. By selecting "Accept essential cookies" you agree to the use of these cookies.

Disease ⇒ HIV infection {40000212}

Record Keys

Details

Meta Information

Notes:

Shared Reference Notes

References Notes

Common References