Disease ⇒ Diarrhea {40000426} Record Keys Type:Disease Parent:[ ] Definition:Diarrhea Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:10012735 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Irritable bowel syndrome] - #Gastroparesis (delayed stomach emptying), #Dysphagia (difficulty swallowing), and #Constipation were associated with over double the risk of #Parkinson’s Disease in the 5 years preceding the diagnosis, while IBS without diarrhea was associated with a 17 per cent higher risk [1.2] [#Irritable bowel syndrome] - #Serotonin levels are increased in both patients with diarrhea predominant and #Constipation predominant IBS. - increased levels of 5-HT in patients with diarrhea predominant IBS in both fasting and fed conditions, whereas patients with #Constipation predominant IBS did not show increased levels of 5-HT after meal ingestion. References Notes[ ]