Clostridiales ⇒ Bifidobacteria {10000259}

Shared Reference Notes

• [1.1] 
  - The reduction of Bifidobacteria, the main producers of lactic acid capable of suppressing the growth of pathogenic bacteria, leads to an alteration of the immunitary system.
• [1.2] [#High-fiber diet] 
  - Dietary fiber > competitive advantage to Bifidobacteria
• [1.3] 
  - Loss of Bifidobacterium early in life has been associated with increased risk of developing autoimmunity, as seen in a birth cohort in Finland and atopic wheeze in another cohort in rural Ecuador.
• [1.4] [#Premature infant] 
  - At the phylum level, #Firmicutes were the dominant phylum in 95% of all meconium samples (highest abundance observed in the VPT neonates as compared to PT and FT neonates); the second most dominant phylum was Bacteroidetes in 50% of all meconium samples.
• [1.5] [#Antibiotic Therapy] 
  - Macrolide exposure was associated with reduced richness for twice as long as penicillin. - Antbiotic at childhud > reduced Bifidobacteria (5 studies) and #Lactobacillus (2 studies), and significant increases in #Proteobacteria such as E. coli (4 studies).
• [1.6] [#Garlic] 
  - #Garlic fructan were found to selectively stimulate the growth of beneficial Bifidobacteria from human fecal microflora.
• [1.7] [#Covid-19] 
  -anti-inflammatory bacteria, including Bifidobacteria species and #Eubacterium rectale, with lower severity, and pro-inflammatory bacteria such as #Prevotella copri with higher severity.
• [1.8] 
  - #Anthocyanins promote an increase in beneficial bacteria, including #Lactobacilli and Bifidobacteria, while reducing pathogenic bacteria, including Staphylococcus aureus and Salmonella typhimurium.
• [1.9] [#Consumption of Inulin-Type Fructans (ITF)] 
  - #Butyrate production may also be driven by bacteria unable to degrade inulin type fructans, but are capable of consuming #Acetate, producing #Butyrate, and utilising partially degraded carbohydrate from bifidobacteria.
• [#Autism] - The depletion of #Bifidobacterium species has been reported widely in ASD. - Bifidobacteria are SCFA producers, and “psychobiotics” , and they modulate the gut–brain signals via γ-aminobutyric acid (GABA) and #Glutamate metabolism. - #Bifidobacterium have been reported to improve behavior and prevent #Depression-like behaviors in mice.

References Notes