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Vitamin B12 {90000185}

Record Keys


Biotic:
Vitamin B12
Parent:[  ]
Queue:[  ]

Details


Initialisation date:
2021-06-30
Specification:
[  ]
Source:
[  ]

Meta Information


Structural Type:[  ]
Functional Type:
Vitamin
Function:
Neurodevelopment

Notes:


[  ]

References Notes


[  ]

Shared Reference Notes


  • [1.1
    - Low B-12 not only causes central nervous system (CNS) damage by decreasing availability of methyl groups, but also allows accumulation of homocysteine, which appears to be toxic to nerve cells and blocks N-methyl-dasparate receptors.
    - It is also important to remember that for B-12 by itself to be functional, it needs to be converted to glutathionyl cobalamin, which requires glutathione for its synthesis. Oxidative stress can tie up glutathione and contribute further to lack of B-12 function.

Common References


  • [1.1] Are We Overlooking B-12 Deficiency as a Cause of Dementia? [2021] [Case study] [80001892]