Pectin {90000129}
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Definition: | Pectin |
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Initialisation date: | 2021-02-02 |
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Specification: | |
- Pectin is a major component of plant cell walls | |
Source: | |
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Structural Type: | [ ] |
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Functional Type: | [ ] |
Function: | Anti-inflammatory |
Notes:
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Shared Reference Notes
- [1.1]
- [1.2]
- The dietary fiber pectin is shown to prevent this intestinal inflammation through direct inhibition of TLR2 in a microbiota-independent manner. - Inhibition of TLR2 is determined by the number and distribution of methyl-esters of pectins. - The degree of methyl-esterification (DM) and the degree of blockiness (DB) of pectins determine attenuating efficacy on doxorubicin-induced #Intestinal mucositis. - [1.3] [#Citrobacter rodentium]
- Pectins > anti-inflammatory properties on intestinal immunity > direct interactions on Toll-like receptors (TLRs) in the small intestine or via stimulating microbiota-dependent effects in the large intestine. - Pectins> prevent C. rodentium induced colonic inflammation > lowering the C. rodentium load in the caecum independently of the DB. - [1.4] [#High fibre diet]
- Dietary fibre is comprised of both soluble and insoluble carbohydrates and includes pectin, cellulose, lignin, hemicellulose, #Arabinoxylan, nondigestible oligosaccharide #Inulin, #Oligofructose and #Resistant Starch. - - #Apple pectin was three times more effective in promoting #Bacteroides growth and overall microflora diversity than #Inulin
- [#Clostridiales XIV] - pectin, which make up 35% of fruit fibre cell wall, increases #Butyrate-producing species such as Clostridium cluster XIV
- [1.5]
- Some oligosaccharides are originated from a #Polysaccharide known as pectin > pectic oligosaccharide (POS)
References Notes
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