Lachnospiraceae ⇒ Dorea {10000312}

Shared Reference Notes

• [1.1] [#Inflamatory bowel disease] 
  - Dorea belongs to the Lachnospiraceae family, which was recently associated with IBD and which is also found in IBD patients with low short-chain fatty acid butyrate.
• [1.2] 
  - Dorea is consistently associated with advanced MAFLD and #Steatohepatitis
• [1.3] [#Gastric bypass surgery] 
  - #Lactococcus, #Streptococcus, and #Granulicatella are #Lactate-producing microorganisms, whereas Dorea and #Blautia are #Lactate oxidizers
• [1.4] [#Crohn’s disease] [#Clostridium cluster IV] 
  - #Roseburia, #Gemmiger, #Coprococcus, #Ruminococcus 2, #Butyricicoccus, Dorea, #Fusicatenibacter, #Anaerostipes, Clostridium IV were enriched in the healthy controls. - #Blautia, Clostridium IV, #Coprococcus, Dorea, #Fusicatenibacter continued to significantly decrease in early and advanced CD patients, and Escherichia/Shigella and Proteus continued to significantly increase. - negative correlation between Dorea, #Butyricicoccus, #Roseburia and gland reduce, #Roseburia and FC, #Butyricicoccus and goblet cells decreased, Parabacterodies and sex, Clostridium IV and CRP, Dorea and ESR . - positive correlation between Escherichia/Shigella and CRP, #Ruminococcus 2 and clinical symptoms.

References Notes