Disease
Microbiota ☳
Metabolome
Factor
Porphyromonadaceae ⇒ Parabacteroides {10000239}
Record Keys
Parent:
Definition: Parabacteroides
Details
Initialisation date: 2020-09-22
Meta Information
Rank:
Domain:
Zone: [ ]
Enzyme: [ ]
Function: Cholesterol-interacting
Notes:
[ ] Shared Reference Notes
[1.1 ] [#Diabetes Type 2 ] - Parabacteroides is positively associated with diabetes.
[1.2 ] [#Short Chain Fatty Acid ] - Parabacteroides > SCFA-producing > richer in the cecum and colorectum > more SCFAs were produced.
[1.3 ] [#Hypertension ] [#Flavonoid ] [#Flavonoid-Rich Foods ]
[1.4 ] - #Obesity > expansion of Escherichia shigella in obese patients compared to healthy controls.
- The family #Eubacterium coprostanoligenes and #Tannerellaceae , the genera #Eubacterium coprostanoligenes , #Lachnospiraceae NK4A136, Parabacteroides , and Akkermansia, and the species #Prevotella copri were microbial biomarkers of healthy people.
- #Gammaproteobacteria and #Enterobacterales were biomarkers of being “Overweight”.
[1.5 ] [#Crohn’s disease ] - #Lachnospiraceae incertae sedis and Parabacteroides were enriched in the early CD patients.
[1.6 ] - resistant #Maltodextrin > increase genus Parabacteroides
[1.7 ] [#Bipolar disorder , #Major depressive disorder , #Schizophrenia ] - MDD was often characterized by higher #Alistipes and Parabacteroides and lower #Prevotella ; BD by higher #Bifidobacterium and #Oscillibacter ; and SZ by higher #Prevotella and lower #Bacteroides , #Haemophilus , and #Streptococcus
[1.8 ] - Certain microorganisms, including #Bifidobacterium , #Escherichia spp., #Bacteroides , and Parabacteroides , produce #GABA , which is an inhibitory neurotransmitter
[1.9 ] [#Soybean ] - high intake of milk and soy beverages was associated with a higher abundance of beneficial faecal microbes including #Faecalibacterium , #Bifidobacterium , and Parabacteroides .
- consumption of fermented soy milk was associated with increased abundance of #Bifidobacterium , bifidobacteria and/or Lactobacillus compared to unfermented soy milk.
- Parabacteroides had significantly higher relative abundances in the #Allergic rhinitis
- A similar correlation with high absolute tissue eosinophil counts and percentages of tissue eosinophils is also seen in the abundance of the genera Parabacteroides , #Bifidobacterium , #Bacteroides , #Microbacterium , #Faecalibacterium , #Lactococcus , #Desulfovibrio , and #Ruminococcus .
[1.11 ] [#Clostridium cluster IV ] - TNF-α was found to be positively correlated with the abundance of Parabacteroides , #Bilophila , and #Clostridium IV, but negatively correlated with the abundance of #Prevotella .
[1.12 ] - #Behcet’s Disease > Stool samples were enriched with Parabacteroides , sulphate-reducing bacteria #Bilophila and #Desulfovibrionaceae species. In addition, it was also noted that #Butyrate -producing bacteria #Clostridium and methanogens were reduced.
- Transplantation of BD faeces in mice illustrated remarkable results in which gut integrity was breached due to decreased expression of tight junctions, with the subsequent effects of experimental uveitis.
[1.13 ] - a positive association of #Propionate with the phylum #Bacteroidota and many of its genera, including #Bacteroides and Parabacteroides .
[#Lachnospiracea ] - The relatively higher proportion of #Acetate and #Propionate in the #Inulin group could be partially explained by the higher abundance of #Parasutterella , #Bacteroides , and Parabacteroides , and as well as the lower prevalence of Lachnospiraceae_NK4A136 and #Faecalibaculum
[1.14 ] [#Christensenellaceae , #Prevotellaceae ] [#Short Chain Fatty Acid ] - #Berberine > the relative abundances of Parabacteroides , Prevotellaceae_UCG-001, and Prevotellaceae_NK3B31_group increased, the relative abundance of Christensenellaceae_R-7_group decreased, and cecal SCFA levels (#Acetic acid and #Propionic acid ) were reduced.
[1.15 ] [#Escherichia coli ] - #Vitamin B12 supplementation in mice significantly decreased Parabacteroides and #Lactobacillus and increased E. coli and #Enterococcus abundances in a murine model of #Colitis
[1.16 ] [#Pulmonary tubercolosis , #Tuberculosis ] - The genera Parabacteroides , #Bacteroides , #Lachnoclostridium , and #Fusobacterium were markedly enhanced in the PTB group, while #Roseburia , #Blautia , unidentified #Ruminococcaceae , #Bifidobacterium , #Romboutsia , and #Fusicatenibacter were enhanced in the HC group.
[1.17 ] [#Parabacteroides distasonis ] - members of the genus Parabacteroides including Parabacteroides distasonis were previously found to be decreased in #Autoimmune disease
[1.18 ] [#Multiple Sclerosis ] - Individuals with relapsing-remitting MS have an abundance of #Mycoplasma , #Pseudomonas , #Faecalibacterium , #Haemophilus , #Anaerostipes , #Blautia , and #Dorea , while #Bacteroides , #Prevotella , Parabacteroides , and #Adlercreutzia are relatively less common.
[1.19 ] [#Multiple Sclerosis ] - Several gut bacteria lacking in MS such as #Prevotella , Parabacteroides , #Adlercreutzia , and #Bifidobacterium can metabolize dietary #Phytoestrogen .
Intervention in Disease [ ]
Author: MetaBiom
Identifier: 10000239
URL: https://www.metabiom.org/microbiota/134/parabacteroides
Keywords: Microbiome, Dysbiosis, Microbiota, Organism, Bacteria
Common References
[1.1 ] Gut microbiome profiles associated with steatosis severity in metabolic associated fatty liver disease [2021] [Research] [Hepatoma Research] [Journal] [80001824 ]
[1.2 ] Maternal Vegetable and Fruit Consumption during Pregnancy and Its Effects on Infant Gut Microbiome [2021] [Clinical study] [Nutrients] [Journal] [80001899 ]
[1.3 ] Microbial Diversity and Abundance of Parabacteroides mediate the Associations Between Higher Intake of Flavonoid-Rich Foods and Lower Blood Pressure
_ REPEATED 2093 [2021] [Research] [Hypertension] [Journal] [80002027 ]
[1.4 ] Gut Microbiota Signature of Obese Adults Across Different Classifications [2022] [Study] [Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy] [Journal] [80002655 ]
[1.5 ] Gut microbiota in the early stage of Crohn’s disease has unique characteristics [2022] [Study] [Gut Pathogens] [Journal] [80002734 ]
[1.6 ] An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson’s disease participants [2023] [Cohort study] [Nature communications] [Journal] [80002769 ]
[1.7 ] Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities [2023] [Review] [Molecular Psychiatry] [Journal] [80002837 ]
[1.8 ] Comparative in-silico analysis of microbial dysbiosis discern potential metabolic link in neurodegenerative diseases [2023] [Review] [Frontiers in Neuroscience] [Journal] [80002870 ]
[1.9 ] Soy and Gastrointestinal Health: A Review [2023] [Review] [Nutrients] [Journal] [80002876 ]
[1.10 ] Alterations of nasal microbiome in eosinophilic chronic rhinosinusitis [2023] [Journal of Allergy and Clinical Immunology] [Journal] [80003049 ]
[1.11 ] Gut microbiota and its relation to inflammation in patients with bipolar depression: a cross-sectional study [2023] [Annals of General Psychiatry] [Journal] [80003100 ]
[1.12 ] The Link Between Gastrointestinal Microbiome and Ocular Disorders [2023] [80003145 ]
[1.13 ] Resistant starches from dietary pulses modulate the gut metabolome in association with microbiome in a humanized murine model of ageing [2023] [Scientific Reports] [Journal] [80003237 ]
[1.14 ] Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine [2022] [Journal of Pharmaceutical Analysis] [Journal] [80003303 ]
[1.15 ] B Vitamins and Their Roles in Gut Health [2022] [Microorganisms] [Journal] [80003304 ]
[1.16 ] Host Microbiome in tuberculosis: Disease, treatment, and immunity perspectives [80003344 ]
[1.17 ] Reproducible and opposing gut microbiome signatures distinguish autoimmune diseases and cancers: a systematic review and meta-analysis [2022] [Microbiome] [Journal] [80003358 ]
[1.18 ] Neuropsychiatric and Neurological Diseases in Relation to the Microbiota-Gut-Brain Axis: From Research to Clinical Care [2023] [Review] [80003409 ]
[1.19 ] Diet‐microbiome‐immune interplay in multiple sclerosis: Understanding the impact of phytoestrogen metabolizing gut bacteria [2023] [European Journal of Immunology] [Journal] [80003449 ]
[1.20 ] Gut microbiota compositional and functional fingerprint in patients with alcohol use disorder and alcohol-associated liver disease [2020] [Liver International] [Journal] [80001386 ]
[1.21 ] The alteration of gut microbiome and metabolism in amyotrophic lateral sclerosis patients [2020] [Scientific Reports] [Journal] [80001425 ]
[1.22 ] Alterations in the human gut microbiome in anti-N-methyl-D-aspartate receptor encephalitis [2019] [Annals of Clinical and Translational Neurology] [Journal] [80001157 ]
[1.23 ] Lower airway microbiota and mycobiota in children with sever asthma [2018] [Journal of Allergy and Clinical Immunology] [Journal] [80001065 ]
[1.24 ] Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture [2019] [Scientific Reports] [Journal] [80000949 ]
[1.25 ] Helicobacter pylori infection aggravates dysbiosis of gut microbiome in children with gastritis [2019] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001277 ]
[1.26 ] Disturbance of trace element and gut microbiota profiles as indicators of autism spectrum disorder: a pilot study of Chinese children [2019] [Environmental Research] [Journal] [80000909 ]
[1.27 ] A metagenomic study of the gut microbiome in Behcet’s disease [2018] [Microbiome] [Journal] [80000793 ]
[1.28 ] Gut microbiota changes in patients with bipolar depression [2019] [Advanced Science] [Journal] [80001106 ]
[1.29 ] Alteration of the gut microbiota in Chinese population with chronic kidney disease [2017] [Scientific Reports] [Journal] [80000616 ]
[1.30 ] Altered diversity and composition of gut microbiota in Chinese patients with chronic pancreatitis [2019] [Pancreatology] [Journal] [80001241 ]
[1.31 ] Gut microbiome patterns depending on children’s psychosocial stress: reports versus biomarkers [2019] [Brain, Behavior, and Immunity] [Journal] [80001328 ]
[1.32 ] Hepatocellular carcinoma is associated with gut microbiota profile and inflammation in nonalcoholic fatty liver disease [2018] [Hepatology] [Journal] [80000791 ]
[1.33 ] Composition of gut microbiota in patients with toxigenic Clostridioides (Clostridium) difficile: Comparison between subgroups according to clinical criteria and toxin gene load [2019] [PLOS ONE] [Journal] [80001022 ]
[1.34 ] The gut microbiota in collagenous colitis shares characteristics with inflammatory bowel diseas-associated dysbiosis [2019] [Clinical and Translational Gastroenterology] [Journal] [80001117 ]
[1.35 ] A metagenome-wide association study of gut microbiota in type 2 diabetes. [2012] [Nature] [Journal] [80000240 ]
[1.36 ] Gut microbial dysbiosis in individuals with Sjögren’s syndrome [2020] [Microbial Cell Factories] [Journal] [80001407 ]
[1.37 ] Intestinal microbiota is altered in patients with gastric cancer from Shanxi Province, China [2019] [Digestive Diseases and Sciences] [Journal] [80001028 ]
[1.38 ] Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma [2018] [Gut] [Journal] [80000859 ]
[1.39 ] Alterations of the gut microbiome in hypertension [2017] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000630 ]
[1.40 ] Altered gut microbiota composition associated with eczema in infants [2016] [PLOS ONE] [Journal] [80000741 ]
[1.41 ] Microbiome analytics of the gut microbiota in patients with juvenile idiopathic arthritis: a longitudinal observational cohort study [2019] [Arthritis & Rheumatology] [Journal] [80001040 ]
[1.42 ] Evidence for a distinct gut microbiome in kidney stone formers compared to non-stone formers [2016] [Urolithiasis] [Journal] [80000544 ]
[1.43 ] Altered fecal microbiota composition in patients with major depressive disorder. [2015] [Brain, Behavior, and Immunity] [Journal] [80000265 ]
[1.44 ] Gut microbiota in early pediatric multiple sclerosis: a case-control study [2016] [European Journal of Neurology] [Journal] [80000269 ]
[1.45 ] Microbiota stratification identifies disease-specific alterations in neuro-Behcet’s disease and multiple sclerosis [2019] [Clinical and Experimental Rheumatology] [Journal] [80001269 ]
[1.46 ] Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities [2019] [Scientific Reports] [Journal] [80001220 ]
[1.47 ] Diversity analysis of gut microbiota in osteoporosis and osteopenia patients [2017] [PeerJ] [Journal] [80001198 ]
[1.48 ] Identification and characterization of blood and neutrophil-associated microbiomes in patients with severe acute pancreatitis using next-generation sequencing [2018] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000703 ]
[1.49 ] Unraveling gut microbiota in Parkinson’s Disease and Atypical Parkinsonism [2019] [Movement Disorders] [Journal] [80000955 ]
[1.50 ] Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis [2019] [Alimentary Pharmacology & Therapeutics] [Journal] [80001214 ]
[1.51 ] Dysbiosis of gut microbiota was closely associated with psoriasis [2019] [Science China Life Sciences] [Journal] [80001218 ]
[1.52 ] Tissue-Associated Bacterial Alterations in Rectal Carcinoma Patients Revealed by 16S rRNA Community Profiling [2016] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000432 ]
[1.53 ] Alterations in the gut microbiota of patients with silica-induced pulmonary fibrosis [2019] [Journal of Occupational Medicine and Toxicology] [Journal] [80000939 ]
[1.54 ] Dysbiosis of gut microbiota with reduced tremethylamine-N-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack._DUBLICATE [2015] [Journal of the American Heart Association] [Journal] [80000456 ]
[1.55 ] Association of Gut Microbiome and Vitamin D Deficiency in Knee Osteoarthritis Patients: A Pilot Study [2021] [Research] [Nutrients] [Journal] [80001797 ]
[1.56 ] Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis [2018] [Scientific Reports] [Journal] [80000689 ]
[1.57 ] Mild cognitive impairment has similar alterations as Alzheimer’s disease in gut microbiota [2019] [Alzheimer's & Dementia] [Journal] [80001081 ]
[1.58 ] Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis. [2017] [Genome Biology] [Journal] [80000612 ]
[1.59 ] Sex-specific associations of infants’ gut microbiome with arsenic exposure in a US population [2018] [Scientific Reports] [Journal] [80000820 ]
[1.60 ] New evidences on the altered gut microbiota in autism spectrum disorders [2017] [Microbiome] [Journal] [80000956 ]
[1.61 ] Alterations of gut microbiome in autoimmune hepatitis [2019] [Gut] [Journal] [80001159 ]
[1.62 ] Impact of cigarette smoking on the middle meatus microbiome in health and chronic rhinosinusitis [2015] [International forum of allergy & rhinology] [Journal] [80000887 ]
[1.63 ] Altered gut microbiota composition in subjects infected with Clonorchis sinensis [2018] [Frontiers in Microbiology] [Journal] [80000846 ]
[1.64 ] Comparison of gut microbiome in human colorectal cancer in paired tumor and adjacent normal tissues [2020] [OncoTargets and Therapy] [Journal] [80001290 ]
[1.65 ] Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer [2012] [PLOS ONE] [Journal] [80000305 ]
[1.66 ] Reduced abundance of butyrate-producing bacteria species in the fecal microbial community in Crohn’s Disease. [2016] [Digestion] [Journal] [80000250 ]
[1.67 ] Fungal dysbiosis in mucosa-associated microbiota of Crohn’s disease patients [2016] [Journal of Crohn's and Colitis] [Journal] [80000760 ]
[1.68 ] Implication of the gut microbiome composition of type 2 diabetic patients from northern China [2020] [Scientific Reports] [Journal] [80001348 ]
[1.69 ] Alterations in gut microbiota of gestational diabetes patients during the first trimester of pregnancy [2020] [Frontiers in Cellular and Infection Microbiology] [Journal] [80001364 ]
[1.70 ] Molecular alteration analysis of human gut microbial composition in Graves’ disease patients [2018] [International Journal of Biological Sciences] [Journal] [80000858 ]
[1.71 ] Featured gut microbiomes associated with the progression of chronic hepatitis B disease [2020] [Frontiers in Microbiology] [Journal] [80001369 ]
[1.72 ] Gut microbiome alterations in patients with stage 4 hepatitis C [2016] [Gut Pathogens] [Journal] [80000613 ]
[1.73 ] Effects of HIV viremia on the gastrointestinal microbiome of young MSM [2019] [AIDS] [Journal] [80000959 ]
[1.74 ] Alterations in the gut microbiota associated with HIV-1 infection [2013] [Cell Host & Microbe] [Journal] [80000339 ]
[1.75 ] The gut microbiome in epilepsy [2020] [Microbial Pathogenesis] [Journal] [80001252 ]
[1.76 ] Fungal microbiota dysbiosis in IBD [2017] [Gut] [Journal] [80000756 ]
[1.77 ] The microbiome of translocated bacterial populations in patients with and without inflammatory bowel disease [2018] [Internal Medicine Journal] [Journal] [80000893 ]
[1.78 ] Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. [2011] [Gastroenterology] [Journal] [80000294 ]
[1.79 ] Specific gut microbiome signature predicts the early-stage lung cancer [2020] [Gut microbes] [Journal] [80001413 ]
[1.80 ] Conjuctival dysbiosis in mucosa-associated lyphoid tissue lymphoma [2019] [Scientific Reports] [Journal] [80001109 ]
[1.81 ] Nonalcoholic fatty liver disease is associated with dysbiosis independent of body mass index and insulin resistance [2018] [Scientific Reports] [Journal] [80000685 ]
[1.82 ] Obese individuals with and without Type 2 diabetes show different gut microbial functional capacity and composition [2019] [Cell Host & Microbe] [Journal] [80001082 ]
[1.83 ] Stool microbiota composition in patients with stomach, colon, and rectal neoplasms [2018] [Digestive Diseases and Sciences] [Journal] [80000819 ]
[1.84 ] Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified [2013] [PLOS ONE] [Journal] [80000449 ]
[1.85 ] Obese adolescents with PCOS have altered biodiversity and relative abundance in Gastrointestinal microbiota [2020] [The Journal of Clinical Endocrinology and Metabolism] [Journal] [80001360 ]
[1.86 ] Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. [2011] [Inflammatory Bowel Diseases] [Journal] [80000242 ]
[1.87 ] A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis [2019] [Clinical and Experimental Gastroenterology] [Journal] [80000964 ]
[1.88 ] Characterisation of the faecal microbiota in Japanese patients with paediatric-onset primary sclerosing cholangitis_DUBLICATE [2016] [Gut] [Journal] [80000335 ]
[1.89 ] Decreased bacterial diversity characterizes an altered gut microbiota in psoriatic arthritis and resembles dysbiosis of inflammatory bowel disease. [2015] [Arthritis Rheumatol] [Journal] [80000525 ]
[1.90 ] The fecal microbiome in pediatric patients with short bowel syndrome. [2015] [Journal of Parenteral and Enteral Nutrition] [Journal] [80000244 ]
[1.91 ] Altered mucosal microbiome diversity and disease severity in Sjögren Syndrome [2016] [Scientific Reports] [Journal] [80000347 ]
[1.92 ] Urogenital schistosomiasis is associated with signatures of microbiome dysbiosis in Nigerian adolescents [2019] [Scientific Reports] [Journal] [80000952 ]
[1.93 ] Faecal microbial dysbiosis in children with Wiskott-Aldrich syndrome [2020] [Journal of Immunology] [Journal] [80001296 ]
[1.94 ] Separating the Empirical Wheat From the Pseudoscientific Chaff: A Critical Review of the Literature Surrounding Glyphosate, Dysbiosis and Wheat-Sensitivity [2020] [Review] [Frontiers in Microbiology] [Journal] [80001476 ]
[1.95 ] How Discrimination Gets Under the Skin: Biological Determinants of Discrimination Associated with Dysregulation of the Brain-Gut Microbiome System and Psychological Symptoms [2022] [Study] [Biological Psychiatry] [Journal] [80002702 ]