Porphyromonadaceae ⇒ Parabacteroides {10000239}

Shared Reference Notes

• [1.1] [#Diabetes Type 2] 
  - Parabacteroides is positively associated with diabetes.
• [1.2] [#Short Chain Fatty Acid] 
  - Parabacteroides > SCFA-producing > richer in the cecum and colorectum > more SCFAs were produced.
• [1.3] 
  - #Obesity > expansion of Escherichia shigella in obese patients compared to healthy controls. - The family #Eubacterium coprostanoligenes and #Tannerellaceae, the genera #Eubacterium coprostanoligenes, #Lachnospiraceae NK4A136, Parabacteroides, and Akkermansia, and the species #Prevotella copri were microbial biomarkers of healthy people. - #Gammaproteobacteria and #Enterobacterales were biomarkers of being “Overweight”.
• [1.4] [#Crohn’s disease] 
  - #Lachnospiraceae incertae sedis and Parabacteroides were enriched in the early CD patients.
• [1.5] 
  - resistant #Maltodextrin > increase genus Parabacteroides
• [1.6] [#Bipolar disorder, #Major depressive disorder, #Schizophrenia] 
  - MDD was often characterized by higher #Alistipes and Parabacteroides and lower #Prevotella; BD by higher #Bifidobacterium and #Oscillibacter; and SZ by higher #Prevotella and lower #Bacteroides, #Haemophilus, and #Streptococcus
• [1.7] 
  - Certain microorganisms, including #Bifidobacterium, #Escherichia spp., #Bacteroides, and Parabacteroides, produce #GABA, which is an inhibitory neurotransmitter
• [1.8] [#Soybean] 
  - high intake of milk and soy beverages was associated with a higher abundance of beneficial faecal microbes including #Faecalibacterium, #Bifidobacterium, and Parabacteroides. - consumption of fermented soy milk was associated with increased abundance of #Bifidobacterium, bifidobacteria and/or Lactobacillus compared to unfermented soy milk.
• [1.9] 
  - Parabacteroides had significantly higher relative abundances in the #Allergic rhinitis
• - A similar correlation with high absolute tissue eosinophil counts and percentages of tissue eosinophils is also seen in the abundance of the genera Parabacteroides, #Bifidobacterium, #Bacteroides, #Microbacterium, #Faecalibacterium, #Lactococcus, #Desulfovibrio, and #Ruminococcus.
• [#Clostridium cluster IV] - TNF-α was found to be positively correlated with the abundance of Parabacteroides, #Bilophila, and #Clostridium IV, but negatively correlated with the abundance of #Prevotella.
• [1.11] 
  - #Behcet’s Disease > Stool samples were enriched with Parabacteroides, sulphate-reducing bacteria #Bilophila and #Desulfovibrionaceae species. In addition, it was also noted that #Butyrate-producing bacteria #Clostridium and methanogens were reduced. - Transplantation of BD faeces in mice illustrated remarkable results in which gut integrity was breached due to decreased expression of tight junctions, with the subsequent effects of experimental uveitis.
• [1.12] 
  - a positive association of #Propionate with the phylum #Bacteroidota and many of its genera, including #Bacteroides and Parabacteroides.
• [#Lachnospiracea] - The relatively higher proportion of #Acetate and #Propionate in the #Inulin group could be partially explained by the higher abundance of #Parasutterella, #Bacteroides, and Parabacteroides, and as well as the lower prevalence of Lachnospiraceae_NK4A136 and #Faecalibaculum
• [1.13] [#Christensenellaceae, #Prevotellaceae] [#Short Chain Fatty Acid] 
  - #Berberine > the relative abundances of Parabacteroides, Prevotellaceae_UCG-001, and Prevotellaceae_NK3B31_group increased, the relative abundance of Christensenellaceae_R-7_group decreased, and cecal SCFA levels (#Acetic acid and #Propionic acid) were reduced.
• [1.14] [#Escherichia coli] 
  - #Vitamin B12 supplementation in mice significantly decreased Parabacteroides and #Lactobacillus and increased E. coli and #Enterococcus abundances in a murine model of #Colitis
• [1.15] [#Pulmonary tubercolosis, #Tuberculosis] 
  - The genera Parabacteroides, #Bacteroides, #Lachnoclostridium, and #Fusobacterium were markedly enhanced in the PTB group, while #Roseburia, #Blautia, unidentified #Ruminococcaceae, #Bifidobacterium, #Romboutsia, and #Fusicatenibacter were enhanced in the HC group.
• [1.16] [#Parabacteroides distasonis] 
  - members of the genus Parabacteroides including Parabacteroides distasonis were previously found to be decreased in #Autoimmune disease
• [1.17] [#Multiple Sclerosis] 
  - Individuals with relapsing-remitting MS have an abundance of #Mycoplasma, #Pseudomonas, #Faecalibacterium, #Haemophilus, #Anaerostipes, #Blautia, and #Dorea, while #Bacteroides, #Prevotella, Parabacteroides, and #Adlercreutzia are relatively less common.
• [1.18] [#Multiple Sclerosis] 
  - Several gut bacteria lacking in MS such as #Prevotella, Parabacteroides, #Adlercreutzia, and #Bifidobacterium can metabolize dietary #Phytoestrogen.
• [1.19] [#Autism] 
  - increased bacterial taxa in ASD phenotype > #Clostridia, #Sarcina and Parabacteroides, among others.
• [#High fibre diet] - F_NL had more fiber-degrading microorganisms like #Bacteroides thetaiotaomicron, #Bacteroides xylanisolvens, #Roseburia sp., #Coprococcus eutactus and Parabacteroides along with the highest number of genes encoding carbohydrate-active enzymes and gene richness.
• [1.21] 
  - Parabacteroides, which possess physiological characteristics related to carbohydrate metabolism and the secretion of short-chain fatty acids, have recently been reported to be closely associated with host health, such as #Metabolic syndrome, inflammatory bowel disease, and #Obesity, as inflammatory mediators
• - the predominant pro-inflammatory bacteria in the #Vitamin A Deficit group consist of microbial communities such as Parabacteroides and #Tannerellaceae.
• [1.22] [#COPD Exacerbation] 
  - In COPD > the relative abundance of #Lachnospira and #Coprococcus was negatively related to the #Smoking index and positively related to lung function results. - The relative abundance of Parabacteroides was positively correlated with the #Smoking index and negatively correlated with lung function findings.
• [1.23] [#Diabetes Type 2] 
  - #Streptococcus and #Eggerthella were relatively more abundant than in prediabetic fecal samples. - #Bacteroides, #Phascolarctobacterium, Parabacteroides, and #Paraprevotella were more abundant in prediabetic fecal samples.

References Notes