Sphingolipids {90000401} Record Keys Parent:[ ] Definition:Sphingolipids Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Chronic fatigue syndrome] [#Alistipes putredinis] [#Ceramides] - Decreased PC 30:0 correlated with decreased A. putredinis, , a bacterium known to produce #Sulfonolipids - unusual sphingolipids structurally related to ceramide. Sphingolipids are known to maintain bacterial survival and promote stress resistance. [1.2] [#Ceramides, #Sphingolipid] [1.3] - Sphingolipids can be produced by the intestinal symbiotic bacteria #Bacteroidetes and #Prevotellaceae. - sphingolipids can also aggravate intestinal inflammation. [1.4] - #Bacteroides spp. with #Serine palmitoyltransferase (SPT) gene have the ability to produce sphingolipids. [#Chronic fatigue syndrome] - elevated levels of serum lipid profile and high #Bacteroidetes were appeared simultaneously in long-term ME/CFS patients [1.5] [#Diabetes Type 2] - sphingolipids play a role in the development of diabetes and the emergence of vascular complications [1.6] [#Atopic Dermatitis] [#Roseomonas mucosa] - The production of sphingolipids by R. mucosa, cholinergic signaling, and #Flagellin expression may have contributed to therapeutic impact through induction of a TNFR2-mediated epithelial-to-mesenchymal transition. References Notes[ ]
