Streptococcaceae ⇒ Streptococcus {10000167}

Shared Reference Notes

• [1.1] [#Gastric carcinoma] 
  - #Aquabacterium, Streptococcus and #Lachnospiraceae > predict gastric cancer. - patients with low levels of Streptococcus and #Lachnospiraceae > more likely to live with gastric cancer without it getting worse. - Patient > more bacterial genes involved in the breakdown of #D-galacturonate > play a key role in the development of gastric cancer
• [1.2] [#Steatohepatitis] 
  - Duodenal dysbiosis with a dominance shift toward specific potential pathogenic bacteria genera (Streptococcus, #Shuttleworthia, #Rothia), increased IP and elevated markers of microbial translocation characterized AUD patients with progressive ALD (steato-hepatitis, steato-fibrosis).
• [1.3] [#Lactobacillus paracasei] 
  - The #Fibrosis-triggering microbial populations in the cecum as mucolytic bacteria : the species #Mucispirillum schaedleri, the genus #Ruminococcus, and the genus #Anaeroplasma, and in the ileum, such as the genera Streptococcus and Lactobacillus.
• [1.4] [#Sleep Deprivation] 
  - Streptococcus was negatively correlated with the concentration of fecal #Butyrate and positively correlated with the KEGG pathway of #Lipopolysaccharide biosynthesis.
• [1.5] [#Neuromyelitis optica] 
  - patients with NMO spectrum disorders > significant increase in the abundance of Streptococcus, which is corrected with immunomodulatory drugs.
• [1.6] 
  - Due to the reduction in oxygen concentration along the longitudinal axis, the upper gastrointestinal tract is the residence of Gram-positive cocci, such as #Gemella and Streptococcus.
• [1.7] 
  - every standard deviation increase in Streptococcus abundance was associated with 1.14 times the risk of #Lung cancer
• [1.8] [#Gastric bypass surgery] 
  - #Lactococcus, Streptococcus, and #Granulicatella are #Lactate-producing microorganisms, whereas #Dorea and #Blautia are #Lactate oxidizers
• [1.9] 
  - Increased abundance of #Acidovorax, #Devosia, #Methylobacterium, #Phascolarctobacterium, and Streptococcus in the peritoneal fluid of #Endometriosis patients
• - women with #Endometriosis had elevated #Gardnerella, Streptococcus, #Escherichia, #Shigella, and #Ureoplasma in their cervix and elevated #Shigella/#Escherichia in their stool
• [#Diabetes Type 1, #Diabetes Type 2] - Compared to the levels in non-diabetic individuals, diabetes patients exhibited a higher abundance of #Neisseria, TM7, #Gemella, #Eikenella, #Selenomonas, #Actinomyces, #Capnocytophaga, #Fusobacterium, #Aggregatibacter, #Veillonella, and Streptococcus genera and a lower abundance of Filifactor, Synergistetes, Tannerella, Eubacterium, Porphyromonas, and Treponema genera
• [1.11] [#Natural Skin Microbiome] [#Infants] 
  - Infant skin > 21 bacterial phyla with #Proteobacteria, #Firmicutes, #Actinobacteria, and #Bacteroidetes being the most abundant. - the relative abundance of #Burkholderiaceae and #Staphylococcus, highly abundant after birth, decreased progressively, to the benefit of newly colonizing taxa such as Streptococcus, #Veillonella, and #Enhydrobacter aerosaccus
• [1.12] [#Bipolar disorder, #Major depressive disorder, #Schizophrenia] 
  - MDD was often characterized by higher #Alistipes and #Parabacteroides and lower #Prevotella; BD by higher #Bifidobacterium and #Oscillibacter; and SZ by higher #Prevotella and lower #Bacteroides, #Haemophilus, and Streptococcus
• [#Bipolar disorder, #Major depressive disorder] - MDD and BD had more commonalities, including higher #Enterococcus, #Flavonifractor, and Streptococcus, and lower #Faecalibacterium and #Ruminococcus.
• [1.13] [#Infants] 
  - Bacterial genera commonly found in the infant small intestine include #Lactobacillus, #Clostridium, #Staphylococcus, Streptococcus, #Bacteroides, and #Bifidobacterium
• [1.14] [#Bacteroides-Prevotella group, #Clostridium III] 
  - in neurodegenerative disease > Streptococcus, #Shigella, #Desulfovibrio, Christensenelia, and #Akkermansia muciniphila have the #Putrescine III synthesis pathway and belong to the elevated microbes group.
• - in neurodegenerative disease > The microbes with elevated populations, like #Bilophila, Butryicicoccus, #Alistipes, #Enterococcus, #Lactobacillus, Streptococcus, #Shigella, and #Desulfovibrio, have the metabolic capability to produce #Putrescine majorly by the #Putrescine III biosynthesis pathway.
• - In neurodegenerative diseases > #Histamine and other important #Neurotransmitters were synthesized in reduced amounts by the microbes with an elevated population in the diseased state. - Most of the microbes, except #Desulfovibrio, #Lactobacillus, and Streptococcus, showed no annotation in their #Genome to synthesize #Histamine.
• - in neurodegenerative disease > #Shigella, #Lactobacillus, and Streptococcus are such microbes with elevated populations and the highest PS for the #Putrescine III biosynthetic pathway.
• [1.15] [#Atherosclerosis, #Rheumatic Hearth Disease] [#Porphyromonas gingivalis] 
  - Oral microbes, including P. gingivalis, #Actinomyces, Streptococcus, and #Treponema denticola, have been confirmed as sources of infected heart valves, atherosclerotic plaques, and rheumatic heart valves
• [#Atherosclerosis] - the existence of #Veillonella and Streptococcus in atherosclerotic plaques, whose bacterial abundances positively correlated with their abundance in the oral cavity, indicating that oral #Veillonella probably spread to extraoral organs via the circulatory system
• [#Periodontal abscess] [#Fusobacterium nucleatum] - patients with F. nucleatum or Streptococcus pepticus bacteremia are more likely to suffer from subsequent #Colorectal cancer
• [#Diabetes Type 2] - In periodontitis-associated type 2 diabetes (T2D), Streptococcus and #Veillonella are dominant in the symbiosis network, and microbial shifts may contribute to systemic inflammation and metabolic dysfunction
• [#Primary sclerosing cholangitis] [#Roseomonas mucosa, #Streptococcus salivarius] - Even in the early stages, PSC patients’ stool and mucosa significantly enrich oral pathogenic bacteria such as Streptococcus, #Veillonella, and #Actinomyces (Streptococcus salivarius is an independent predictor of liver-related three-year mortality)
• [1.16] 
  - Higher proportions of #Bacteroidetes, namely #Prevotella, and lower proportions of #Firmicutes (Streptococcus, #Veillonella, #Gemella, and #Lactobacillaceae) are found in the duodenum compared with the jejunum.
• [#Natural Small intestine Microbiome] [#Escherichia coli] - At the genus level, bacteria highly abundant in the SI include #Lactobacillus, #Veillonella, Streptococcus, #Gemella, #Actinomyces, and E. coli.
• [1.17] 
  - Regarding microbial composition, Streptococcus is the most abundant genus in mucosal tissue, representing 44–55% of the detected genera, which can also be found in other specimens such as plaque and saliva.
• [1.18] 
  - Other important #Firmicutes genera are #Listeria, #Paenibacillus, #Staphylococcus, Streptococcus, #Pediococcus, and #Leuconostoc.
• - In healthy human stomach, the genera Streptococcus, #Prevotella, #Veillonella, #Rothia, and #Haemophilus were found to be predominant.
• [1.19] [#Candida albicans, #Streptococcus mutans] 
  - The presence of C. albicans would increase the abundance of Streptococcus (particularly S. mutans), certain #Lactobacillus species, and salivary #Veillonella and #Prevotella, and also increase the cariogenic virulence of biofilms
• [#Cancer, #Melanoma] - An #Immune checkpoint inhibitor (ICI)-favorable response was characterized by an intestinal microbiome rich in bacteria such as #Oscillospira sp., #Clostridia UCG-014, #Lachnospiraceae UCG-010 sp., #Prevotella copri, and a decrease in #Sutterella sp., #Lactobacillales, and Streptococcus sp. - Patients who developed immune-related adverse events (irAEs) had an overall increased microbial diversity and richness, and a stool microbiome depleted in #Agathobacter.
• [1.21] [#CVD] 
  - CACS-associated species was negatively associated with the microbially derived #Tryptophan metabolite #Indole #Propionate, a metabolite that has been found inversely associated with atherosclerotic coronary disease in humans and reduced progression of #Atherosclerosis in mice.
• [#Atherosclerosis] - The Streptococcus genus was associated with coronary artery calcium score (CACS)
• [#Atherosclerosis] - genes related to anaerobic fermentation of fatty acids were associated with CACS-associated species
• [#Atherosclerosis] - oral bacteria such as #Veillonella spp and Streptococcus spp found in the oral cavity, fecal samples, and carotid atherosclerotic plaque.9 Given the association between dental health and endothelial dysfunction and atherosclerotic disease,
• [#Atherosclerosis] - issimilatory #Nitrate reduction > CACS-associated species > converts #Nitrate to #Ammonia, and having an increased activity of this pathway in the colon could potentially inhibit the potential positive cardiovascular effects of #Nitrate.
• [#Atherosclerosis] [#Smoking] - Several tobacco metabolites (ie, 3-hydroxycotinine glucuronide, cotinine N-oxide, and norcotinine) were positively associated with species positively associated with CACS and negatively associated with species negatively associated withcoronary artery calcium score (CACS).
• [1.22] [#Systemic lupus erythematosus] 
  - The genus Streptococcus was associated with the lupus activity
• [1.23] 
  - an increase of #Bifidobacterium and #Eggerthella in #Infants who succeeded on at least one of the point and gaze subtests, while having a lower abundance of #Hungatella and Streptococcus.
• [1.24] 
  - #Lactococcus and Streptococcus possess a complete pathway for the de novo #Folate biosynthesis and do not require a supply of either DHPPP or pABA
• [1.25] 
  - Streptococcus and #Enterococcus produce #Serotonin
• [1.26] 
  - Some oral bacteria belonging to genera #Lactobacillus, #Lactococcus, #Bifidobacterium, Streptococcus, #Leuconostoc, and #Pediococcus produce #Lactic acid
• [#Cancer] [#Alcohol Consumption] - Genus #Neisseria had extremely high ADH activity and produced significant amounts of #Acetaldehyde in vitro. - #Neisseria’s ability to produce #Acetaldehyde was more than 100-fold higher than that produced by Streptococcus sp., Stomatococcus sp., or #Moraxella sp. - #Neisseria can be a regional source of carcinogenic #Acetaldehyde and may thus play an essential role in alcohol-related carcinogenesis in humans
• [#Oral squamous cell carcinoma] - specific bacteria have been identified that correlate strongly with Oral squamous cell carcinomas (OSCCs), such as Streptococcus sp., #Peptostreptococcus sp., #Prevotella sp., #Porphyromonas gingivalis, and #Capnocytophaga gingivalis
• [#Oral squamous cell carcinoma] - most often observed oral bacteria in OSCCs are Streptococcus sp., #Peptostreptococcus sp., #Prevotella sp., #Porphyromonas gingivalis, and #Capnocytophaga gingivalis
• [#Oral squamous cell carcinoma] - OSCC tumor sites are highl associated with the following species: Streptococcus sp., #Peptostreptococcus stomatis, #Gemella sp., and #Johnsonella ignava
• [1.27] 
  - patients with #Celiac Disease showed the abundance of Streptococcus, #Lactobacillus, #Veillonella, and #Allisonella species, while the abundance of #Ruminococcus, #Faecalibacterium, #Blautia, #Gemmiger, and #Anaerostipes was decreased.
• [1.28] [#Parkinson’s Disease] 
  - The increase of Streptococcus species, which can sometimes cause permanent neurological damage by secreting neurotoxins, has been associated with immuno-inflammatory pathways in PD. - Streptococcus species are higher in stool samples of PD patients
• [1.29] [#Genome] 
  - In addition to #Bifidobacterium and #Lactobacillus, our study found a significant enrichment of Streptococcus, a #Lactic acid-producing bacteria, in patients with #Ulcerative Colitis (UC). - This is in contrast to the majority of earlier studies from west. - This increase in Streptococcus abundance has also been observed in UC patients from different populations.
• [#Gastric bypass surgery] - Roux-en-Y gastric bypass (RYGB) resulted in clear alteration in composition of gut fungal and bacterial microbiota. - Before surgery, patients had higher levels of #Firmicutes and #Actinobacteria and lower levels of #Verrucomicrobia - #Faecalibacterium and #Bifidobacterium showed a decrease after surgery and aerotolerant Streptococcus was increased postoperatively. - The relative abundance of #Proteobacteria was increased after surgery. - Changes in fungal microbiota composition included decreases in #Candida and #Saccharomyces and increases in #Pichia. - levels of #Verrucomicrobia and #Proteobacteria increased after the surgery procedure - Bifidobacteriaceae abundance decreased, whereas Streptococcaceae and Enterobacteriaceae increased after surgery. - RYGB led to increased #Firmicutes and #Actinobacteria phyla but decreased #Bacteroidetes phylum
• [1.31] 
  - #Staphylococcus and Streptococcus species, #Corynebacterium species may serve as novel pathogenic candidate microbes for #Vasculitis.
• [1.32] 
  - levels of #TMAO in cystic fluid were positively correlated with bacterial clusters corresponding to Enterobacteriacea, #Granulicatella, #Klebsiella, #Stenotrophomonas, Streptococcus, #Haemophilus, and #Fusobacterium > associated with #Pancreatic Cancer.
• [1.33] 
  - Patients with #Primary biliary cirrhosis were found to show enrichment of #Actinobacteria, #Lactobacillales, Streptococcus, #Klebsiella and #Veillonella
• [#Primary immune thrombocytopenia] - fecal bacteria such as #Actinomycetaceae, #Blautia, Streptococcus, and #Lactobacillus are enriched, whereas bacteria such as #Bacteroides are depleted in ITP patients.
• [#Primary immune thrombocytopenia] [#Streptococcus anginosus, #Streptococcus parasanguinis, #Streptococcus salivarius] - #Lactobacillus and Streptococcus (including S. anginosus, Streptococcus sp., S. parasanguinis, and S. salivarius) were enriched in ITP patients.
• [1.34] [#Skin aging] [#Streptococcus infantis, #Streptococcus pneumoniae] [#Aging] 
  - younger Korean women carried a higher amount of skin Streptococcus compared to older Korean women. - These Streptococcus species, specifically Streptococcus (St.) pneumoniae and St. infantis, can secrete substances that up-regulate #Collagen synthesis.
• [1.35] [#Natural oral microbiomes] [#Infants] 
  - similar to the #Adult oral microbiome, the infant oral microbiome is dominated by Streptococcus
• [1.36] 
  - The respiratory microbiota primarily consists of bacteria such as #Prevotella, #Veillonella, and Streptococcus
• [1.37] [#Natural Skin Microbiome] [#Actinobacteria] 
  - Belly button (BB) and between toes (BT) (moist microenvironment) were mainly comprised of Actinobacteriota and #Firmicutes; behind ears (BE) (oily microenvironment) was dominated by #Firmicutes; and calves (CA) and forearms (FA) (dry microenvironment) included a combination of those three phyla. - BB and BT (moist microenvironment) were dominated by #Staphylococcus and #Corynebacterium, BE (oily microenvironment) by #Staphylococcus and #Anaerococcus, while CA and FA (dry microenvironment) showed a high proportion of #Staphylococcus and #Corynebacterium, but also of Streptococcus and #Escherichia-#Shigella. #Anaerococcus was also highly abundant in BB.
• [1.38] 
  - #Lactobacillus, #Bacillus, #Corynebacterium, Streptococcus, #Pseudomonas, #Staphylococcus, #Escherichia-#Shigella were observed to decrease in Viral #Keratitis microbiomes. And the abundance of some opportunistic pathogens such as #Rhodococcus were increased.
• [1.39] [#Alzheimer’s disease] 
  - Streptococcus bacteria have been detected in the brain microbiome from AD patients
• - Streptococcus and #Veillonella enrichment in #Lung cancer brushings have been associated with upregulation of phosphoinositide 3-kinases (PI3K); pPI3Ks, also known as phosphatidylinositol 3-kinases and extracellular signal-regulated kinase (ERK) pathways, are an enzyme group involved in cellular processes such cell growth, proliferation, differentiation, motility, survival, and intracellular trafficking that are proposed to have a role in promoting growth, migration, treatment resistance, and metastasis in most lung cancers.
• [1.41] 
  - decreased abundance of #Clostridiales bacterium in the stools of #Bladder cancer patients, but increased Streptococcus and #Escherichia.
• [1.42] [#Dry eye syndrom] 
  - Streptococcus and #Pedobacter bacteria species were the most prevalent microbes in healthy eyes while more #Acinetobacter species were present in the eye microbiomes of people with dry eye.
• [1.43] [#Multiple Sclerosis, #Periodontal disease] 
  - Among the oral microbiota, five genera (#Dialister, #Aggregatibacter, #Catonella, Streptococcus, and #Paludibacteriaceae-F0058) had a decreased relative abundance in the MS cohort. Interestingly, the first three genera have also been shown to be associated with periodontal diseases
• [1.44] 
  - #Asthma exacerbations > higher abundance of #Staphylococcus and “oral” taxa, including #Neisseria, #Veillonella, and Streptococcus spp. and a lower abundance of #Dolosigranulum pigrum, #Corynebacterium, and #Moraxella spp.
• - #Asthma exacerbations > #Neisseria abundance was associated with more severe disease. - #Neisseria spp. abundance was also related with fine particulate matter exposure, whereas #Haemophilus and Streptococcus abundances were related with recent inhaled #Corticosteroid use.
• [1.45] [#Diabetes Type 2] 
  - Streptococcus and #Eggerthella were relatively more abundant than in prediabetic fecal samples. - #Bacteroides, #Phascolarctobacterium, #Parabacteroides, and #Paraprevotella were more abundant in prediabetic fecal samples.
• [1.46] [#Idiopathic Pulmonary Fibrosis] [#Streptococcus mitis] 
  - IPF > The buccal proportion of Streptococcus correlated positively with FVC. - IPF > Greater microbial diversity was associated with an increased risk of death while a greater proportion of Streptococcus was associated with a reduced risk of death. - IPF > The Streptococcus genus was mainly comprised of Streptococcus mitis species. - IPF > The oral commensal Streptococcus mitis spp associates with preserved lung function and improved survival.
• [1.47] [#Streptococcus danieliae] [#Quinolinic acid] [#High Fat Diet] 
  - QA can improve the intestinal flora disorder by reducing the abundance of Streptococcus danieliae, or promoting the abundance of #Lactobacillus intestinalis and #Ileibacterium valens in HFD-induced Apoe−/− mice.
• [1.48] [#Anthocyanins] 
  - Subtle differences were observed in the faecal microbiota of subjects that were fed the different apples, with significant reductions in relative abundances of Streptococcus, #Ruminococcus, #Blautia, and #Roseburia, and increased relative abundances of #Sutterella, #Butyricicoccus, and #Lactobacillus in subjects after consuming the red #Apple. - anthocyanin-rich apples may influence immune function compared to control apples
• [1.49] [#Metabolic associated fatty liver disease] 
  - #Ruminiclostridium and Streptococcus were enriched in patients with #Obesity and MAFLD. - these changes remained significant for #Ruminococcaceae UCG-008 even after correction for multiple comparisons
• [#Chronic liver disease] - A higher relative abundance of the genus Streptococcus was reported in the duodenal microbiota of subjects with alcoholic liver disease and chronic liver diseas.
• [1.51] 
  - acute and chronic #Nitrate exposure decreased #Caries-associated #Veillonella and Streptococcus decreased .

References Notes