Streptococcus ⇒ Streptococcus anginosus {10000547} Record Keys Parent:Streptococcus Definition:Streptococcus anginosus Details Initialisation date:[ ] Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Streptococcus agalactiae, #Streptococcus gordonii, #Streptococcus oralis, #Streptococcus parasanguinis] - S. anginosus, S. oralis subsp oralis, S. parasanguinis, S. gordonii, and S. agalactiae were associated with coronary #Atherosclerosis. - These species all belong to the viridans group streptococci (VGS), except for S. agalactiae (a β-hemolytic non-VGS). - VGS can enter the bloodstream through mucosal barrier injuries from daily dental care activities and dental procedures, and could also pass the gut barrier when injured. - VGS can invade human aortic endothelial cells and stimulate #Atherosclerosis-related proinflammatory cytokines [1.2] [#Esophageal cancer, #Head & Neck cancer, #Oral cancer] - Among streptococci, Streptococcus anginosus seems to be an especially relevant marker of head, neck, and esophageal cancers [1.3] [#Primary immune thrombocytopenia] [#Streptococcus parasanguinis, #Streptococcus salivarius] - #Lactobacillus and #Streptococcus (including S. anginosus, #Streptococcus sp., S. parasanguinis, and S. salivarius) were enriched in ITP patients. [#Primary immune thrombocytopenia] - a strong negative correlation was found between platelet count and altered gut microbiota such as S. anginosus and gut metabolites such as Cer (t18:0/16:0) in ITP. [#Primary immune thrombocytopenia] - S. anginosus not only increased 35-fold in its relative abundance from ITP patients to HCs, but was also highly negatively correlated to platelet count. [#Primary immune thrombocytopenia] - combinations of #Weissella and Streptococcus anginosus, or Cer (t18:0/16:0), Cer (d18:1/17:0), and #13-hydroxyoctadecanoic acid could provide good diagnostic markers for ITP. - S. anginosus strain NCTC10713T, showed clear β-hemolysis on blood agar plates. - #Streptolysin S produced from this strain exhibited a cytotoxic potential similar to that produced by #Streptococcus pyogenes. [1.4] [#Bladder cancer] - the #Howardella genus and the Streptococcus anginosus strain were more common in women. - no differences in the diversity of urine between sexes; however, in the urine of women, there was a higher abundance of the genera #Lactobacillus, Actinotignum, #Prevotella, #Veillonella, and #Campylobacter.References Notes[ ]
