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Microbiome & Chronic Diseases

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Disease ⇒ Heart failure {40000230}

Record Keys
Type:
Disease
Parent:[  ]
Definition:
Heart failure

Details
Initialisation date:[  ]
Other Terms:
HF

Meta Information
MedDra ID:
10019285
MedDra Level:
llt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:

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Shared Reference Notes

  • [1.1] [#CVD, #Hearth attack] 
  • [1.2] [#Eubacterium hallii, #Lachnospiraceae, #Ruminococcaceae] 
    - patients with HF have a decrease in #Butyrate-producing bacteria, especially, Lachnospiracea and Ruminococcacea families. - reduction of the #Butyrate-producing Eubacterium Halli and Lachnospiracea is correlated with increased inflammation, severity of disease, heart damage and mortality
  • [1.3] 
    - #TMAO levels are also associated with heart failure and #Coronary artery disease. - #TMAO enhances the responsiveness of platelets to multiple agonists, promoting platelet hyperactivity and thus thrombosis and subsequent cardiovascular disease.
  • [1.4] 

References Notes

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