Disease ⇒ Obstructive sleep apnea-hypopnea syndrome {40000400}
| Type: | Disease |
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| Parent: | [ ] |
| Definition: | Obstructive sleep apnea-hypopnea syndrome |
| Initialisation date: | [ ] |
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| Other Terms: | OSAHS |
| MedDra ID: | 10040979 |
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| MedDra Level: | pt |
| ICD: | [ ] |
| Category: | [ ] |
| Zone: | [ ] |
| Mechanism: | [ ] |
Notes:
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Shared Reference Notes
- [1.1] [#Fecal Microbiota Transplantation]
- IH-FMT mice exhibited increased aBP and TMAO levels, and impairments in aortic and coronary artery function that were abrogated by #Probiotic administration. - [1.2]
- Intermittent hypoxia associated with obstructive #Sleep apnea (OSA) is associated with Gut Microbiota composition and diversity changes. - [1.3] [#Hypertension]
- the OSA-related hypoxia parameters were associated with the relative abundance of 128 gut bacterial species, including higher abundance of #Blautia obeum and #Collinsella aerofaciens. - #Collinsella aerofaciens was also independently associated with increased systolic BP. - - OSA-related hypoxia, but not the number of apneas/hypopneas, is associated with specific gut microbiota species and functions. - the cumulative time in hypoxia during sleep was associated with the abundance of genes involved in nine gut microbiota metabolic pathways, including #Propionate production from #Lactate.
- [1.4]
- OSAS patients presented higher #Melatonin levels in the afternoon than control subjects who did not snore. - The #Melatonin secretion pattern in OSAS patients shows values in a plateau without the nocturnal peak found in healthy control subjects.
References Notes
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