Lactobacillales ⇒ Lactobacillaceae {10000750}

Shared Reference Notes

• [1.1] [#Chronic kidney disease] 
  - #Curcumin > significantly reduced plasma pro-inflammatory mediators (CCL-2, IFN-γ, and IL-4) and lipid peroxidation. - After 6 months of #Curcumin supplementation > significantly lower #Escherichia-#Shigella and significantly higher #Lachnoclostridium . - In the last 3 months of supplementation > significantly higher Lactobacillaceae spp..
• [1.2] [#Depression] [#Limosilactobacillus (Lactobacillus) reuteri] [#Probiotic (Bifidobacter and Lactobacilus)] 
  - Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > reduction in depressive symptoms at four and eight weeks of treatment, and #Anxiety symptoms at four weeks. > improvement in #Sleep quality. - Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > decrease in serum interleukin-6 levels. - Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > increased #Bifidobacteriaceae and Lactobacillacea, whereas it decreased #Enterobacteriaceae in the gut microbiota composition.
• [1.3] [#Metabolic Dysfunction-associated Steatohepatitis, #Metabolic associated fatty liver disease] 
  - median portal vein #Ethanol concentrations were 187 (interquartile range (IQR), 17–516) times higher and increased with disease progression from 2.1 mM in individuals without steatosis to 8.0 mM in NAFL 21.0 mM in nonalcoholic steatohepatitis. - Inhibition of ADH induced a 15-fold (IQR,1.6- to 20-fold) increase in peripheral blood #Ethanol concentrations in individuals with NAFLD, although this effect was abolished after antibiotic treatment. - Lactobacillaceae correlated with postprandial peripheral #Ethanol concentrations.
• [1.4] [#Bile Acids] 
  - Lactobacillaceae BSHs display a clear bias for either #Glycine or #Taurine-conjugated BAs.
• [1.5] 
  - Higher proportions of #Bacteroidetes, namely #Prevotella, and lower proportions of #Firmicutes (#Streptococcus, #Veillonella, #Gemella, and Lactobacillaceae) are found in the duodenum compared with the jejunum.
• [#Natural Small intestine Microbiome] [#Smoking] - In the SI lumen, the abundance of #Prevotellaceae, #Neisseriaceae, and #Porphyromonadaceae is reduced in smokers, whereas #Enterobacteriaceae and Lactobacillaceae abundances are increased.
• [1.6] [#Irritable bowel syndrome] 
  - IBS patients have increased levels of the bacterial families #Enterobacteriaceae, Lactobacillaceae, and #Bacteroidales, whereas #Bifidobacterium, #Faecalibacterium, and #Clostridiales were decreased compared with healthy controls.
• [1.7] [#Clostridioides difficile] [#Para-cresol] 
  - p-Cresol is an aromatic derivative of #Tyrosine produced as a catabolite by many members of the gut microbiota, including some #Bifidobacteriaceae, #Enterobacteriaceae, #Clostridiaceae, Lactobacillaceae, #Coriobacteriaceae, and #Bacteroidaceae. - #Clostridia difficile has displayed a particular growth advantage on p-cresol and people with #Autism spectrum disorders often have a gut microbiome that is enriched in #Clostridia.
• [1.8] [#Systemic lupus erythematosus] 
  - Lactobacillaceae significantly decreased and #Lachnospiraceae significantly increased in lupus-prone MRL/lpr mice. - Increased intestinal abundance of Lactobacillaceae was associated with improvement of lupus symptoms, while increased colonization of #Lachnospiraceae was associated with disease progression
• [1.9] [#Spondyloarthritis] 
  - significant increases in the class #Bacilli, order #Lactobacillales, families Lactobacillaceae and #Clostridiaceae, and genera #Lactobacillus and #Clostridium in non-colonized SpA patients.
• [#Lipopolysaccharide] [#Sleep Deprivation] - SF (Sleep Frgamentation) modifies the gut microbiome, leading to an elevation in the #Lachnospiraceae family and a decline in the Lactobacillaceae family. - The former is associated with intestinal inflammation, whereas the latter acts as a protective barrier. - SF lowers antioxidant capacity and depletes the number of goblet cells and colonocyte proliferation.36 It also intensifies LPS-binding protein circulation levels and stimulates an enhanced inflammatory response.

References Notes