Streptococcus ⇒ Streptococcus pyogenes {10001496} Record Keys Parent:Streptococcus Definition:Streptococcus pyogenes Details Initialisation date:[ ] Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Short peptide bacteriocins] - #Subtilosin A, an SPB produced by #Bacillus subtilis, which is capable of exerting strong inhibitory activity against Streptococcus pyogenes at a very low concentration (1.25 µg/mL), but against #Streptococcus gordonii had an MIC value of 83.25 µg/mL [1.2] [#Streptococcus anginosus] - S. anginosus strain NCTC10713T, showed clear β-hemolysis on blood agar plates. - #Streptolysin S produced from this strain exhibited a cytotoxic potential similar to that produced by Streptococcus pyogenes. - A small fraction of #Children with S. pyogenes infections was reported to develop #Sydenham’s chorea or pediatric autoimmune neuropsychiatric disorders. [1.3] - two receptors on the surface of many immune cells, known as toll-like receptors, lock onto S. pyogenes cardiolipins. - The cells then recognize the bacteria as invaders and call out for release of an inflammatory molecule known as tumor necrosis factor (TNF) alpha. - #Cardiolipin SpCL-1 > additional strategy to stimulate an immune response to fight #Cancer. [1.4] [#Cancer] - Streptococcus pyogenes and lymphangioma: These mediate immune cell sensitization. - Triggered cells that invade the neoplasm, inhibit further growth and minimize lymphangioma > amounts of lymphocytes and neutrophils, and also macrophages, are quickly increasing on the first day after administration of the suspension. - Vascular endothelial growth factor (VEGF), tumor necrosis factor-alpha (TNFα), #IL-6, #IL-8, and NK cell levels also increased.References Notes[ ]
