Neisseriaceae ⇒ Neisseria {10000757} Record Keys Parent:Neisseriaceae Definition:Neisseria Details Initialisation date:[ ] Meta Information Rank: Genus Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:Nitrate-reducing Notes: [ ]Shared Reference Notes [1.1] - Coexisting #Hypertension and #Periodontal disease > increased Neisseria and #Solobacterium genera [1.2] - Microbiota composition and predicted function in #Celiac Disease was largely determined by intestinal location. In the duodenum, but not stool, there was higher abundance of #Escherichia coli, #prevotella salivae, and Neisseria. - Neisseria, an opportunistic pathogen previously found to be increased in patients with active #Celiac Disease, was associated with more severe enteropathy. - Expression of microbial glutamate carboxypeptidase was lower in the duodenum of celiac patients, and its decrease in mice also correlated with impaired gluten degradation, suggesting a potential candidate for future therapeutic development. [1.3] [#Diabetes Type 1, #Diabetes Type 2] - Compared to the levels in non-diabetic individuals, diabetes patients exhibited a higher abundance of Neisseria, TM7, #Gemella, #Eikenella, #Selenomonas, #Actinomyces, #Capnocytophaga, #Fusobacterium, #Aggregatibacter, #Veillonella, and #Streptococcus genera and a lower abundance of Filifactor, Synergistetes, Tannerella, Eubacterium, Porphyromonas, and Treponema genera [1.4] [#Gastric carcinoma] - The oral taxa Neisseria, #Prevotella, and #Veillonella had centralities in tumors with intestinal and mixed phenotypes and were associated with MUC13 overexpression, highlighting their role as potential drivers in MUC13 signaling in GC. [1.5] -The genera Neisseria, #Prevotella and #Haemophilus are also highly abundant, with a prevalence of 6–29%, depending on the site. [1.6] [#Cancer] [#Alcohol Consumption] - Genus Neisseria had extremely high ADH activity and produced significant amounts of #Acetaldehyde in vitro. - Neisseria’s ability to produce #Acetaldehyde was more than 100-fold higher than that produced by #Streptococcus sp., Stomatococcus sp., or #Moraxella sp. - Neisseria can be a regional source of carcinogenic #Acetaldehyde and may thus play an essential role in alcohol-related carcinogenesis in humans [1.7] [#Parkinson’s Disease] [#Bacteroides-Prevotella group] - #Mycoplasma faucium, #Tannerella forsythia, #Parvimonas micra, and #Saccharibacteria (#TM7) were increased in P; #Prevotella pallens, #Prevotella melaninogenica, Neisseria multispecies were more abundant in PA+P group, #Ruthenibacterium lactatiformans, #Dialister succinatiphilus, #Butyrivibrio crossotus and #Alloprevotella tannerae were detected in fecal samples in P groups compared to healthy controls. [1.8] - #Asthma exacerbations > higher abundance of #Staphylococcus and “oral” taxa, including Neisseria, #Veillonella, and #Streptococcus spp. and a lower abundance of #Dolosigranulum pigrum, #Corynebacterium, and #Moraxella spp. - #Asthma exacerbations > Neisseria abundance was associated with more severe disease. - Neisseria spp. abundance was also related with fine particulate matter exposure, whereas #Haemophilus and #Streptococcus abundances were related with recent inhaled #Corticosteroid use. [1.9] - acute and chronic #Nitrate exposure increased (representatives of) health-associated Neisseria and #Rothia whilst reducing #Periodontal disease-associated #Prevotella . [#Blautia, #Ruminococcus] - Specific human gut microbes, including Ruminococcus_E, #Agathobacter, #Fusicatenibacter, #Anaerobutyricum, Blautia_A and Neisseria, were identified as potential consensus microbial biomarkers for #Obesity in the population.References Notes[ ]