Sleep Deprivation {51111282}
Definition: | Sleep Deprivation |
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Queue: | [ ] |
Initialisation date: | 2022-01-25 |
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Specification: | |
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Type: | Habit |
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Host: | Mouse |
Zone: | [ ] |
Notes:
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Shared Reference Notes
- [1.1]
- fecal #Butyrate concentrations positively correlated with the relative abundance of #Butyricimonas. - the abundance of SCFAs-producing microbes, such as #Butyricicoccus, #Butyricimonas, and #Alistipes markedly decreased after SD. - #Butyrate > significantly reduced after 48 h of SD > After 1 week of sleep recovery, #Butyrate concentrations returned. - - gut microbial composition and metabolites did not change in the rats after 24 h of SD but were significantly altered after 48 h of Sleep Deprivation > reversible after 1 week of sleep recovery. - After 48 h of SD, the relative abundance of Butyricicoccus, Butyricimonas, Alistipes, Intestinimonas, and Lactobacillus decreased, whereas the relative abundance of Streptococcus increased.
- - #Streptococcus was negatively correlated with the concentration of fecal #Butyrate and positively correlated with the KEGG pathway of #Lipopolysaccharide biosynthesis.
- [1.2]
- Decreases in SCFA-producing bacteria, specifically belonging to #Akkermansia and #Faecalibacterium genera, have also been detected in mice subject to 7-day paradoxical sleep deprivation and 3-day continuous sleep deprivation. - Decreases in Bifidobacterium and Lactobacillus genera have been seen in mice subject to 5 days of sleep disruption. - sleep deprivation–induced dysbiosis in mice resulted in increased intestinal permeability and reduced abundance of SCFAs, features that were both reversed following subsequent administration of #Lactobacillus plantarum. - [1.3] [#Alzheimer’s disease]
- #Sleep deprivation exacerbates AD pathology, which clearly connects poor #Sleep quality with progression of AD. - [1.4]
- Dietary #Polyphenol Preparation (BDPP) containing GSPE, concord #Grape juice and #Resveratrol was shown to attenuate sleep deprivation-induced contextual memory deficits.
References Notes
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