Lactobacillus ⇒ Lactobacillus paracasei {10001819} Record Keys Parent:Lactobacillus Definition:Lactobacillus paracasei Details Initialisation date:2022-01-24 Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:Fibrosis-triggering Notes: [ ]Shared Reference Notes [1.1] - L. paracasei subsp. paracasei CNCM I-1518 has been demonstrated to prevent the adhesion and invasion of Escherichia coli in vitro, limit chemically-induced gut injuries, and enhance antimicrobial activity in vitro. - L. paracasei subsp. paracasei CNCM I-1518 have a high survivability in the gastrointestinal tract of mice and humans, which is an important indication of the potential functionality of the probiotic strain. - L. paracasei subsp. paracasei CNCM I-1518 modulates the molecules involved in humoral and cell-mediated immune responses. - Fermented dairy products containing L. paracasei subsp. paracasei CNCM I-1518 and the standard yogurt cultures may modulate biomarkers of immune function , as well as immune responses [1.2] - The #Fibrosis-triggering microbial populations in the cecum as mucolytic bacteria : the species #Mucispirillum schaedleri, the genus #Ruminococcus, and the genus #Anaeroplasma, and in the ileum, such as the genera #Streptococcus and Lactobacillus. [1.3] [#Irritable bowel syndrome] - Lactobacillus paracasei CNCM I-1572 improves symptoms, modulates gut microbiota structure and function through the reduction of Rumicococcus with consequent increased levels of #Acetate and #Butyrate, and reduces intestinal immune activation in patients with IBS [1.4] [#Probiotic] - the administration of L. paracasei Lpc-37 to subjects with #Chronic stress was found to significantly decrease Perceived stress (PSS). [1.5] [#CVD, #Hypercholesterolaemia] [#Enterococcus faecium] [#Cholesterol] - E. faecium strain 132 and L. paracasei strain 201 may alleviate hypercholesterolemia in rats [#Hypercholesterolaemia] - #Enterococcus faecium strain 132 and Lactobacillus paracasei strain 201 reduced liver inflammation, improved the lipid profile by regulating the gene expression related to #Cholesterol metabolism and reduced fat accumulation. [1.6] [#Metabolic associated fatty liver disease] [#Lactobacillus bulgaricus, #Lactobacillus plantarum] - Randomized controlled trials in NAFLD patients revealed that administration of polymicrobial probiotics (containing #Bifidobacteria, #Lactobacillus acidophilus, L. bulgaricus, L. paracasei, L. plantarum, and #Streptococcus thermophilus) significantly reduced the fatty liver phenotype, inflammation, and #Fibrosis.References Notes[ ]