Peptostreptococcus ⇒ Peptostreptococcus stomatis {10000287} Record Keys Parent:Peptostreptococcus Definition:Peptostreptococcus stomatis Details Initialisation date:2020-10-12 Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Colorectal cancer] [#Parvimonas micra] - four species of two genera are found to be associated with CRC: #Parvimonas micra, #Parvimonas sp., Peptostreptococcus stomatis, and #Peptostreptococcus anaerobius. [1.2] [#Colorectal cancer, #Inflamatory bowel disease] - Regarding IBD and CRC, P. stomatis is among the oral-derived biomarker panel of CRC either - For instance, Peptostreptococcus stomatis engages in gastrointestinal cancers and is of significant centralities in the #Gastric carcinoma (GC) ecological network, which mediates the pathogenesis of precancerous gastric atrophy (GA) and #Intestinal metaplasia (IM) [1.3] [#Cancer] [#Acetic acid, #Butyric acid, #Isobutyric acid, #Isocaproic acid, #Isovaleric acid] - aciduric Peptostreptococcus stomatis produces acetic, butyric, isobutyric, isovaleric, and isocaproic acids. - Production of such acids may contribute to the acidic and hypoxic microenvironment of tumors, thereby increasing metastatic efficiency [#Oral squamous cell carcinoma] - OSCC tumor sites are highl associated with the following species: #Streptococcus sp., Peptostreptococcus stomatis, #Gemella sp., and #Johnsonella ignava [1.4] - #Cancer-associated bacteria are #Fusobacterium nucleatum, Peptostreptococcus stomatis, and #Parvimonas micra [1.5] - Peptostreptococcus stomatis and #Enterococcus faecium were identified as potential contributors to the progression of #Gallbladder cancer [1.6] [#Oral squamous cell carcinoma] - oral cavity squamous cell carcinoma (OSCC) > enrichment in the relative abundance of seven bacteria species (#Fusobacterium nucleatum, #Treponema medium, Peptostreptococcus stomatis, #Gemella morbillorum, #Catonella morbi, #Peptoanaerobacter yurli and #Peptococcus simiae) were observed in OSCC tumor microenvironment. - pathogenic bacteria to regulate gene expression, in part, through epigenetic alterations. [1.7] [#Colorectal cancer] [#Teenager] - well-known CRC-associated taxa, such as #Clostridium symbiosum, Peptostreptococcus stomatis, #Parvimonas micra and #Hungatella hathewayi were significantly enriched in both old- and young-onset patients. - Similar strain-level patterns of #Fusobacterium nucleatum, #Bacteroides fragilis and #Escherichia coli were observed for oCRC and yCRC. - Almost all oCRC-associated metagenomic pathways had directionally concordant changes in young patients.References Notes[ ]
