Disease ⇒ Natural oral microbiomes {40000601} Record Keys Type:Disease Parent:[ ] Definition:Natural oral microbiomes Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - ethnicity was the strongest association with the oral microbiomes. [1.2] [#Colorectal cancer] [#Prevotella intermedia, #Prevotella nigrescens] - A higher abundance of P. intermedia and P. nigrescens (Pretovella species that are commonly resident in the oral cavity) was observed in the intestine of CRC patients - The oral microflora owns the highest level of variation and the most diverse library of unique sequences, whereas this diversity gradually decreases from the oral to the distal gut, indicating that the microbiome undergoes selective pressure. - If successfully reaching the intestine, these intruders are usually pathogenic. [1.3] [#Normal Vaginal condition] - #Veillonella parvula is a biofilm-forming commensal found in the lungs, vagina, mouth, and gastro-intestinal tract of humans [1.4] [#Infants] - similar to the #Adult oral microbiome, the infant oral microbiome is dominated by #Streptococcus [1.5] [#Streptococcus mutans] - #sIgA binds to oral bacteria, such as #Streptococcus mitis, #Streptococcus oralis, and S. mutans, which have epitopes recognized by #sIgA, selectively recruiting these specific bacteria to the mucus layer on the mucosal surfaces of the oral cavity. [1.6] - #Prevotella is a natural component of human microflora commonly found in the oral cavity and saliva [1.7] - Ancient dental calculus > multiple oral microbial communities that coexisted in Britain for millennia, including a community associated with #Methanobrevibacter, an anaerobic #Archaea not commonly prevalent in the oral microbiome of modern industrialized societies.References Notes[ ]
