Negibacteria ⇒ Verrucomicrobia {10001017} Record Keys Parent:Negibacteria Definition:Verrucomicrobia Details Initialisation date:[ ] Meta Information Rank: Phylum Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Lachnospiraceae] - 4 weeks of #Grape powder consumption > significantly increased the alpha diversity index of the gut microbiome > increasing Verrucomicrobia at the phylum level, and a significant increase in #Akkermansia and increase in #Flavonifractor and Lachnospiraceae_UCG-010 > decrease in #Bifidobacterium and #Dialister at the genus level. [1.2] [#Alzheimer’s disease] - Decrease in #Bacteroidetes and #Alloprevotella and increase in #Proteobacteria, Verrucomicrobia, #Akkermansia, and #Desulfovibrio > improve short-term memory ability and cognitive level of AD mice [1.3] [#Diabetes Type 2] - #Black women, regardless of insulin sensitivity > greater relative abundance of the phylum #Actinobacteria, compared to White women. - #Black women with insulin resistance > four fold higher Verrucomicrobia abundance than White women. [1.4] [#Ruminococcaceae] [#High Fat Diet] - HFD > decrease relative abundance of Verrucomicrobia, #Akkermansia , Ruminococcaceae_UCG-014 and #Bifidobacteriaceae [#Bifidobacteriaceae, #Ruminococcaceae] [#Moderate Treadmill Exercise] - Exercise > increase the relative abundance of Verrucomicrobia, #Akkermansia and Ruminococcaceae_UCG-014 [1.5] [#Parkinson’s Disease] - Mucin degrading genus #Akkermansia of the phylum Verrucomicrobia has been widely reported to be significantly abundant in PD by most studies. #Akkermansia and Christensenellaceae may symbiotically play a role in PD pathology and progression [1.6] - In acute #Colitis, #Melatonin led to increased clinical, systemic and intestinal inflammatory parameters. - During remission, continued MLT administration delayed recovery, increased TNF, memory effector lymphocytes and diminished spleen regulatory cells. - MLT treatment reduced #Bacteroidetes and augmented #Actinobacteria and Verrucomicrobia phyla in mice feces. - Microbiota depletion resulted in a remarkable reversion of the #Colitis phenotype after MLT administration, including a counter-regulatory immune response, reduction in TNF and colon macrophages. - There was a decrease in #Actinobacteria, #Firmicutes and, most strikingly, Verrucomicrobia phylum in recovering mice. Finally, these results pointed to a gut-microbiota-dependent effect of MLT in the potentiation of intestinal inflammation. [1.7] - #Akkermansia muciniphila is a mucus-degrading member of the Verrucomicrobia found in the human GI tract. - A. muciniphila represents from 1 to 4% of the bacterial population in the colon. [1.8] - #Propionate is produced by some #Firmicutes, #Bacteroidetes, and Verrucomicrobia, especially #Akkermansia muciniphila [1.9] [#Gastric bypass surgery] - Roux-en-Y gastric bypass (RYGB) resulted in clear alteration in composition of gut fungal and bacterial microbiota. - Before surgery, patients had higher levels of #Firmicutes and #Actinobacteria and lower levels of Verrucomicrobia - #Faecalibacterium and #Bifidobacterium showed a decrease after surgery and aerotolerant #Streptococcus was increased postoperatively. - The relative abundance of #Proteobacteria was increased after surgery. - Changes in fungal microbiota composition included decreases in #Candida and #Saccharomyces and increases in #Pichia. - levels of Verrucomicrobia and #Proteobacteria increased after the surgery procedure - Bifidobacteriaceae abundance decreased, whereas Streptococcaceae and Enterobacteriaceae increased after surgery. - RYGB led to increased #Firmicutes and #Actinobacteria phyla but decreased #Bacteroidetes phylum - enrichment of #Actinobacteria in patients with #Ankylosing spondylitis, and depletion of #Fusobacteria and Verrucomicrobia [1.11] - the gut microbiome of patients with #Chronic periodontitis had a higher abundance of the #Firmicutes, #Proteobacteria, Verrucomicrobia and #Euryarchaeota phylum and a lower abundance of the #Bacteroidetes phylum, plus the diversity of the microbiota was decreased. [1.12] [#Serotonin, #Tryptophan] - #Fructooligosaccharides have been shown to modulate the gut microbial composition, by decreasing the abundance of #Akkermansiaceae (family level) and Verrucomicrobia (phylum level) and increasing the abundance of #Ruminococcaceae (phylum level), and to increase the levels of Trp and 5-HT in mice models [1.13] - Verrucomicrobia possesses anti-inflammatory properties that contribute to intestinal health.References Notes[ ]
