Treponema ⇒ Treponema denticola {10000875} Record Keys Parent:Treponema Definition:Treponema denticola Details Initialisation date:[ ] Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Capnocytophaga gingivalis, #Tannerella forsythia] - Adverse pregnancy outcomes are a broad term containing preeclampsia, low birth weight, preterm premature rupture of membranes, early-onset neonatal sepsis, miscarriage, stillbirth, and fetal growth retardation - The prevalent oral species are #Filifactor alocis, #Fusobacterium nucleatum, Porphyromonas gingivalis, #Campylobacter rectus, T. Denticola, and T. Forsythia, among others. - Stimulated fetal inflammatory and immune responses may ultimately increase the potential for Adverse pregnancy outcomes owing to the virulent properties assigned to microbiota in the intrauterine environment. [1.2] [#Atherosclerosis, #Rheumatic Hearth Disease] [#Porphyromonas gingivalis] - Oral microbes, including P. gingivalis, #Actinomyces, #Streptococcus, and Treponema denticola, have been confirmed as sources of infected heart valves, atherosclerotic plaques, and rheumatic heart valves [1.3] [#Amyloid-beta] - oral inoculation of T. denticola into C57BL/6 mice has been shown to result in the production of Aβ1–42 in the hippocampus and neuronal apoptosis [1.4] [#Fusobacterium nucleatum, #Porphyromonas gingivalis, #Prevotella intermedia, #Tannerella forsythia] - P. gingivalis, T. denticola, T. forsythia, P. intermedia, F. nucleatum and #Filifactor alocis are traditionally recognized as major pathogens responsible for #Periodontal disease [1.5] [#Fusobacterium nucleatum, #Porphyromonas gingivalis] - #Nisin has concentration-dependent antimicrobial activity against Gram-negative periodontopathic bacteria such as P.gingivalis, T.denticola, and F.nucleatumReferences Notes[ ]