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Shared Reference Notes
- [1.1] [#Exercise training]
- Single bout of exercise > upregulated metabolic pathways of skeletal muscle substrate utilization and carbohydrate metabolites in serum > increased fecal ammonia and amino acid metabolites > increased the abundance of #Clostridia
- Ammonia accumulates in tumors and reduces T cell function in vitro and in vivo. - Ammonia decreases T cell transsulfuration leading to altered redox status. - Clearance of ammonia reactivates T cells and decreases #Colorectal cancer.