Bacillaceae ⇒ Bacillus {10000645} Record Keys Parent:Bacillaceae Definition:Bacillus Details Initialisation date:[ ] Meta Information Rank: Genus Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - Bacillus can produce #Dopamine. [1.2] [#Dopamine] - Bacillus spp. produces Dopamin [1.3] - gut microbe–derived metabolite trimethylamine N-oxide (#TMAO), enhanced antitumor immunity to Pancreatic ductal adenocarcinoma (PDAC) - Delivery of #TMAO intraperitoneally or via a dietary choline supplement to orthotopic PDAC-bearing mice reduced tumor growth, associated with an immunostimulatory tumor-associated macrophage (TAM) phenotype, and activated effector T cell response in the tumor microenvironment. - #TMAO potentiated the type I interferon (IFN) pathway and conferred antitumor effects in a type I IFN–dependent manner. - bacteria producing an enzyme that generates #TMA was associated with positive immunotherapy outcomes in people with #Pancreatic Cancer. - Bacillus and #Paenibacillus species, were present at higher levels in people who survived for a long period of time after #Pancreatic Cancer. [1.4] - widespread class of Bacillus lipopeptides, the fengycins, eliminates S. aureus by inhibiting S. aureus quorum sensing—a process through which bacteria respond to their population density by altering gene regulation. - consumption of #Probiotic Bacillus bacteria comprehensively abolished colonization by the dangerous pathogen #Staphylococcus aureus in a rural Thai population. [1.5] - in the patients with #Non-Atopic Dermatitis, an abundance of Bacillus and #Brevibacillus was significantly increased while that of #Corynebacterium was significantly decreased in affected vs. unaffected skin [1.6] - Five bacterial phyla including #Firmicutes, #Bacteroidetes, #Actinobacteria, #Proteobacteria, and #Fusobacteria can participate in #Tryptophan metabolism, being those belonging to the #Clostridium, #Burkholderia, #Streptomyces, #Pseudomonas or Bacillus genera the most important modulators [1.7] [#Bacillus subtilis] - #Myristic acid is involved in the post-translational folding of proteins in humansan d can inhibit the activity of some bacterial ATP-binding cassette (ABC) transporters, for instance, observed for bacillus multidrug-resistance ATP (BmrA) of Bacillus subtilis (B. subtilis). [1.8] - The #Firmicutes phylum comprises Gram-positive bacteria with low G + C DNA content and is composed of more than 200 different genera, such as #Lactobacillus, Bacillus, #Clostridium, #Enterococcus, and Ruminicoccus. [1.9] - Bacillus species produce #Norepinephrine and #Dopamine - #Lactobacillus, Bacillus, #Corynebacterium, #Streptococcus, #Pseudomonas, #Staphylococcus, #Escherichia-#Shigella were observed to decrease in Viral #Keratitis microbiomes. And the abundance of some opportunistic pathogens such as #Rhodococcus were increased. - the bacterial #Keratitis group had a significantly higher abundance of Bacillus and #Megamonas. [1.11] [#Gestational Hypertension, #Hypertension] - Bacillus was associated with high blood pressure [1.12] [#Bisphenol A] - #Enterococcus and Bacillus were the predominant genera isolated in the presence of BPA. Among the genera that were more frequently isolated, we also obtained #Staphylococcus, #Escherichia-#Shigella, and #Clostridium, indicating a possible direct effect of selective pressure by the BPA. [1.13] [#Radiofrequency field] - Bacillus and #Bifidobacterium were the first two bacteria that are notably correlated with most of the differential metabolites, indicating they contribute greatly to the disturbance of microbial metabolism during RF exposure.References Notes[ ]