Bacillaceae ⇒ Bacillus {10000645}

Shared Reference Notes

• [1.1] 
  - Bacillus can produce #Dopamine.
• [1.2] [#Dopamine] 
  - Bacillus spp. produces Dopamin
• [1.3] 
  - gut microbe–derived metabolite trimethylamine N-oxide (#TMAO), enhanced antitumor immunity to Pancreatic ductal adenocarcinoma (PDAC) - Delivery of #TMAO intraperitoneally or via a dietary choline supplement to orthotopic PDAC-bearing mice reduced tumor growth, associated with an immunostimulatory tumor-associated macrophage (TAM) phenotype, and activated effector T cell response in the tumor microenvironment. - #TMAO potentiated the type I interferon (IFN) pathway and conferred antitumor effects in a type I IFN–dependent manner. - bacteria producing an enzyme that generates #TMA was associated with positive immunotherapy outcomes in people with #Pancreatic Cancer. - Bacillus and #Paenibacillus species, were present at higher levels in people who survived for a long period of time after #Pancreatic Cancer.
• [1.4] 
  - widespread class of Bacillus lipopeptides, the fengycins, eliminates S. aureus by inhibiting S. aureus quorum sensing—a process through which bacteria respond to their population density by altering gene regulation. - consumption of #Probiotic Bacillus bacteria comprehensively abolished colonization by the dangerous pathogen #Staphylococcus aureus in a rural Thai population.
• [1.5] 
  - in the patients with #Non-Atopic Dermatitis, an abundance of Bacillus and #Brevibacillus was significantly increased while that of #Corynebacterium was significantly decreased in affected vs. unaffected skin
• [1.6] 
  - Five bacterial phyla including #Firmicutes, #Bacteroidetes, #Actinobacteria, #Proteobacteria, and #Fusobacteria can participate in #Tryptophan metabolism, being those belonging to the #Clostridium, #Burkholderia, #Streptomyces, #Pseudomonas or Bacillus genera the most important modulators
• [1.7] [#Bacillus subtilis] 
  - #Myristic acid is involved in the post-translational folding of proteins in humansan d can inhibit the activity of some bacterial ATP-binding cassette (ABC) transporters, for instance, observed for bacillus multidrug-resistance ATP (BmrA) of Bacillus subtilis (B. subtilis).
• [1.8] 
  - The #Firmicutes phylum comprises Gram-positive bacteria with low G + C DNA content and is composed of more than 200 different genera, such as #Lactobacillus, Bacillus, #Clostridium, #Enterococcus, and Ruminicoccus.
• [1.9] 
  - Bacillus species produce #Norepinephrine and #Dopamine

References Notes