Streptococcus ⇒ Streptococcus parasanguinis {10000891} Record Keys Parent:Streptococcus Definition:Streptococcus parasanguinis Details Initialisation date:[ ] Meta Information Rank: Species Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - Several species were enriched during #Pregnancy compared to the postpartum period including #Streptococcus salivarius and Streptococcus parasanguinis. Both species are also prevalent members of the infant gut microbiome [1.2] [#Streptococcus agalactiae, #Streptococcus anginosus, #Streptococcus gordonii, #Streptococcus oralis] - S. anginosus, S. oralis subsp oralis, S. parasanguinis, S. gordonii, and S. agalactiae were associated with coronary #Atherosclerosis. - These species all belong to the viridans group streptococci (VGS), except for S. agalactiae (a β-hemolytic non-VGS). - VGS can enter the bloodstream through mucosal barrier injuries from daily dental care activities and dental procedures, and could also pass the gut barrier when injured. - VGS can invade human aortic endothelial cells and stimulate #Atherosclerosis-related proinflammatory cytokines [1.3] [#Bacteroides caccae, #Faecalibacterium prausnitzii, #Prevotella copri] [#Immune checkpoint inhibitor] - The most distinctive species associated with ICI treatment response were F. prausnitzii, S. parasanguinis, B. caccae, and P. copri, [1.4] [#Primary immune thrombocytopenia] [#Streptococcus anginosus, #Streptococcus salivarius] - #Lactobacillus and #Streptococcus (including S. anginosus, #Streptococcus sp., S. parasanguinis, and S. salivarius) were enriched in ITP patients.References Notes[ ]