Phosphatidylcholine {90000423} Record Keys Parent:[ ] Definition:Phosphatidylcholine Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:Energy Source Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Bifidobacterium infantis, #Bifidobacterium longum] - phosphatidylcholine is a major membrane-forming phospholipid in eukaryotes, with an estimated presence of 15% in the bacterial kingdom. - phosphatidylcholine exert a prebiotic function on B. longum subsp. infantis, which, by translating the compound to 1,2-sn-diacylglycerols, affects the regulation of colonic mucus production. -#Clostridia and #Enterobacteriaceae could also be involved in phosphatidylcholine metabolism, which decreases the abundance of #Bifidobacterium spp. due to competition for the substrate. [#Human milk lipids] [#Human breast milk] - Phosphatidylcholine, phosphatidylethanolamine, and #Sphingomyelin contribute up to 40% of all MFGM #Phospholipids, which are subject to intra-individual variation, especially during early lactation [1.2] [#Clostridium clusters XIVa] - Components with the[N(CH3)3] structure, such as #Choline, phosphatidylcholine, and L-#Carnitine, can be used by #Clostridium (primarily #Clostridium XIVa and #Eubacterium) and Proteobacterium produced trimethylamine (#TMA) lyases to form #TMA. - #TMA is a foul-smelling gas that smells like rotten fish [1.3] - phosphatidylcholine (PC), #Phosphatidylethanolamine (PE) are remarkably increased in depressed patients and have favorable associations with #Depression severity. - PC and PE might act as a link between gut dysbiosis and depressive-like behaviors.References Notes[ ]