Desulfovibrionales ⇒ Desulfovibrionaceae {10001318} Record Keys Parent:Desulfovibrionales Definition:Desulfovibrionaceae Details Initialisation date:[ ] Meta Information Rank: Family Domain: Bacteria Zone:[ ] Enzyme:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - diet high in EVOO (vs refined #Olive oil, which is devoid of #Polyphenols) to Swiss Webster mice resulted in reduced levels of species in the Desulfovibrionaceae. [#Olive] - EVOO has demonstrated antibacterial and bacteriostatic effects against bacteria such as those in the Desulfovibrionaceae,a family of opportunistic pathogens associated with #Obesity and inflammation, and #Blautia spp., which positively correlates with visceral fat accumulation in Japanese men and women. [1.2] - Desulfovibrionaceae, one of the main intestinal pathogenic bacteria producing endotoxin, has been found to induce the expression of inflammatory factors such as TNF-α, IL-1, and #IL-6 in the intestinal epithelium. [1.3] [#Parkinson’s Disease] - #Hydrogen sulfide produced by several #Enterobacteriaceae and Desulfovibrionaceae can enter host cells, cause the release of cytochrome c protein from mitochondria into the cytoplasm, mediate the accumulation of cytosolic iron and #Reactive Oxygen Species, thus boosting α-synuclein synthesis [1.4] - #Behcet’s Disease > Stool samples were enriched with #Parabacteroides, sulphate-reducing bacteria #Bilophila and Desulfovibrionaceae species. In addition, it was also noted that #Butyrate-producing bacteria #Clostridium and methanogens were reduced. - Transplantation of BD faeces in mice illustrated remarkable results in which gut integrity was breached due to decreased expression of tight junctions, with the subsequent effects of experimental uveitis. [1.5] [#Multiple Sclerosis] - #Children with MS exhibit low levels of #Lachnospiraceae and #Ruminococcaceae and significant levels of Desulfovibrionaceae members [1.6] [#Multiple Sclerosis] [#High Fat Diet] - MS > mice on a high-fat diet showed enrichment of bacteria from the Desulfovibrionaceae family, specifically #Desulfovibrio piger and #Bilophila wadsworthia. - high-fat diet-induced #Obesity increased EAE disease severity in animal models of MSReferences Notes[ ]