Carnitine {60000078}

Shared Reference Notes

• [1.1] [#Alzheimer’s disease] 
• [1.2] [#Atherosclerosis, #Hearth attack] [#Crotonobetaine, #TMAO, #γ-butyrobetaine] [#Meat-based diet] 
• [1.3] [#Egg Consumption, #Meat-based diet] 
  - dietary #Choline or L-carnitine, which are found in foods such as meat and eggs, are metabolized by the gut microbiota into #TMA in the intestine. - #TMA enters the blood circulation and is transformed into #TMAO in the liver.
• [1.4] [#Meat-based diet] 
  - The animal meat-derived metabolites carnitine, #Choline, or #Phosphocholine (PC) are degraded by gut bacteria to trimethylamine (#TMA), which is further metabolized in the liver to trimethylamine N-oxide (#TMAO)
• - The microbiota metabolizes phosphatidylcholine, #Choline, and carnitine to produce trimethylamine (#TMA), which is further metabolized in the liver to trimethylamine-N-oxide (#TMAO).
• [1.5] [#Chronic fatigue syndrome] 
  - altered plasma levels of #Choline, carnitine and complex lipid metabolites.

References Notes