Disease ⇒ Intrahepatic Cholangiocarcinoma {40000448} Record Keys Type:Disease Parent:[ ] Definition:Intrahepatic Cholangiocarcinoma Details Initialisation date:[ ] Other Terms:ICC Meta Information MedDra ID:10008593 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Inflamatory bowel disease] - IBD has been reported to positively affect the incidence of cholangiocarcinoma. - the association may not be direct and instead occur through the mediation of #Primary sclerosing cholangitis [1.2] [#Biliary tract cancer, #Primary liver cancer] - enriched in ICC were #Actinomyces, #Lactobacillus, #Peptostreptococcaceae, and #Alloscardovia. Furthermore, the #Glycoursodeoxycholic acid and #Tauroursodeoxycholic acid (TUDCA) plasma-stool ratios were significantly increased in ICC with the genera #Lactobacillus and #Alloscardovia exhibiting positive correlations with the TUDCA plasma-stool ratio. - These biomarkers could be used to differentiate ICC from hepatocellular carcinoma (HCC) - #Biliary tract cancer intramular microbiome > distinct and tissue-specific microbiome dominated by the families #Dietziaceae, #Pseudomonadaceae, and #Oxalobacteraceae was observed in the bile duct tissues. - The enrichment of specific enteric bacteria (#Bifidobacteriaceae, #Enterobacteriaceae, and #Enterococcaceae) correlated with parasite-associated cholangiocarcinomaReferences Notes[ ]
