Notes:
- P. gingivalis was detected immunohistochemically in 61 % of cancerous tissues, 12 % of adjacent tissues and was undetected in normal esophageal mucosa. A similar distribution of lysine-specific gingipain, a catalytic endoprotease uniquely secreted by P. gingivalis, and P. gingivalis 16S rDNA was also observed.
- P. gingivalis infection positively associated with multiple clinicopathologic characteristics, including differentiation status, metastasis, and overall survival rate. (1)