Microbiome & Chronic Diseases

Evidence Based Medicine
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Helicobacter ⇒ Helicobacter pylori {10000112}

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Helicobacter pylori


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Shared Reference Notes

  • [1.1
    - H. pylori eradication therapy is safe for adolescents with respect to gut microbiota changes associated with H. pylori eradication therapy
  • [1.2] [#Parkinson’s Disease
  • [1.3] [#Alzheimer’s disease
    - Patients with the H. Pylori infection have been found to perform more poorly on the Mini–Mental State Examination, verbal memory tasks, and serial digit learning tasks; the infection causes inflammation and even tau hyperphosphorylation.
  • [#Parkinson’s Disease] - greater prevalence of Helicobacter pylori infection in patients with PD and poorer clinical status in patients with the infection; H. pylori eradication was found to be associated with clinical improvement.
  • [1.4
    - The progression of #Chronic gastritis toward #Gastric carcinoma has been characterized by the reduction in the Helicobacter genus, overgrowth of opportunistic bacteria, increased apoptosis, necrosis, and collagen production, changes in the cytoskeleton and polarity of the gastric epithelium, and gradual suppression of gastric acidity.
  • [#Gastric carcinoma, #Peptic ulcer] - H. pylori has a substantial association with chronic gastritis, gastric ulcer, mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric adenocarcinoma.
  • - Streptococcus, Neisseriae, Prevotella, Rothia, Fusobacterium, Veillonella, and Haemophilus are considered the main gastric bacterial genera enriched in #H. pylori-positive individuals. - the overgrowth of #Candida species in the stomach has been reported during H. pylori infection, which might result in synergistic effects on the H. pylori pathogenesis.
  • - H. pylori association with obesity, diabetes, IBD, allergic disorders, as well as cardiovascular, hepatobiliary, skin, kidney, autoimmune, neurologic, and psychiatric diseases.
  • [1.5] [#Peptic ulcer] [#Antibiotic Therapy
    - The population of #Actinobacteria is decreased by the use of Helicobacter pylori treatment.
  • [1.6] [#Alzheimer’s disease
    - Local periodontal inflammation due to infection with Helicobacter pylori, the agent of gastric ulcers, or with #Porphyromonas gingivalis, in fact, can stimulate brain tissue inflammation

References Notes

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